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  4. Recombinant Mouse Protein shisa-9 (Shisa9), partial

Recombinant Mouse Protein shisa-9 (Shisa9), partial

  • 中文名稱：
    小鼠Shisa9重組蛋白
  • 貨號：
    CSB-YP866643MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Shisa9重組蛋白
  • 貨號：
    CSB-EP866643MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Shisa9重組蛋白
  • 貨號：
    CSB-EP866643MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Shisa9重組蛋白
  • 貨號：
    CSB-BP866643MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Shisa9重組蛋白
  • 貨號：
    CSB-MP866643MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Shisa9
  • Uniprot No.：
  • 別名：
    Shisa9; Protein shisa-9; Cystine-knot AMPAR modulating protein of 44 kDa; CKAMP44
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Regulator of short-term neuronal synaptic plasticity in the dentate gyrus. Associates with AMPA receptors (ionotropic glutamate receptors) in synaptic spines and promotes AMPA receptor desensitization at excitatory synapses.
  • 基因功能參考文獻：
    1. Data indicate the importance of CKAMP44 for modulating synaptic short-term depression and visual input integration. PMID: 29343769
    2. Ckamp44 expression is strongest in dentate gyrus granule cells and less abundant in the rest of the brain PMID: 26645823
    3. coexpression of both auxiliary subunits,CKAMP44 and TARP gamma-8 is necessary for the efficient targeting of AMPARs to the cell surface of dentate gyrus granule cells PMID: 25066086
    4. Data show interaction partners of AMPA receptor auxiliary subunit Shisa9, and that the C-terminal interactions of Shisa9 through its PDZ domain interaction motif are important for AMPA receptor synaptic and network functions. PMID: 24498314
    5. CKAMP44 identified as a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines; findings show that CKAMP44 modulates short-term plasticity at specific excitatory synapses PMID: 20185686

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  • 亞細胞定位：
    Cell projection, dendritic spine membrane; Single-pass type I membrane protein. Cell junction, synapse.
  • 蛋白家族：
    Shisa family, SHISA9 subfamily
  • 組織特異性：
    Brain-specific. Mainly expressed in neurons, including in hippocampus, cerebral cortex, striatum, thalamus, olfactory bulb and cerebellum. Expressed in most brain structures during embryonic and postnatal development.
  • 數(shù)據(jù)庫鏈接：


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