在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Protein bicaudal C homolog 1 (Bicc1), partial

Recombinant Mouse Protein bicaudal C homolog 1 (Bicc1), partial

  • 中文名稱：
    Recombinant Mouse Protein bicaudal C homolog 1(Bicc1) ,partial
  • 貨號：
    CSB-YP858155MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Protein bicaudal C homolog 1(Bicc1) ,partial
  • 貨號：
    CSB-EP858155MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Protein bicaudal C homolog 1(Bicc1) ,partial
  • 貨號：
    CSB-EP858155MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Protein bicaudal C homolog 1(Bicc1) ,partial
  • 貨號：
    CSB-BP858155MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Protein bicaudal C homolog 1(Bicc1) ,partial
  • 貨號：
    CSB-MP858155MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Bicc1
  • Uniprot No.：
  • 別名：
    Bicc1Protein bicaudal C homolog 1; Bic-C
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Putative RNA-binding protein. May be involved in regulating gene expression during embryonic development.
  • 基因功能參考文獻(xiàn)：
    1. Polymerization is a novel disease-relevant mechanism both to stabilize Bicc1 and to present associated mRNAs in specific silencing platforms. PMID: 26217012
    2. discovered that loss of the Pkd1 gene product, polycystin-1 (PC1), whose mutation causes human autosomal dominant polycystic kidney disease (ADPKD), downregulates Bicc1 expression in vitro and in vivo PMID: 24594709
    3. identify Bicc1 as a genetic determinant of osteoblastogenesis and BMD and suggest that it does so by regulating Pkd2 transcript levels PMID: 24789909
    4. Bicc1 is a novel regulator of osteoblastogenesis and bone mineral density (BMD) PMID: 24789909
    5. Bicc1 similarly induces silencing of the protein kinase inhibitor PKIalpha by miR-27a. PMID: 22641646
    6. Bicc1 KH domains bind the 3' UTRs of AC6 and PKIa mRNAs and cognate miRNA precursors, whereas the SAM domain loads a silencing complex with AGO2. AC6 and PKIa protein levels increase in cystic Bicc1-/- mouse kidneys. PMID: 22641646
    7. lack of Bicc1 leads to disruption of normal cell-cell junctions. PMID: 20219263
    8. Data suggest that Bicc1 functions by modulating the expression of polycystin 2 (Pkd2 by antagonizing the repressive activity of the miR-17 microRNA family on the 3'UTR of Pkd2 mRNA. PMID: 20215348
    9. Binds homoribopolymers in vitro; the third K homology domain is necessary and sufficient for in vitro Bicc1 RNA binding. PMID: 18182784
    10. Bicc1 and SamCystin interact at the protein level suggesting that they function in a common molecular pathway that when perturbed, is involved in cystogenesis. PMID: 19324013
    11. Data report that targeted inactivation of BicC randomizes left-right asymmetry by disrupting the planar alignment of motile cilia required for cilia-driven fluid flow, and that BicC can uncouple Dvl2 signaling from the canonical Wnt pathway. PMID: 19666828

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    BicC family
  • 組織特異性：
    In the adult, predominantly expressed in heart and kidney. In 8 week old mice, expressed in growing primary oocytes and in the stromal cells of the theca.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚欧成a人无码精品va片| 亲嘴扒胸摸屁股激烈网站| 窝窝午夜精品一区二区| 自拍区小说区图片区亚洲| 双乳被一左一右吃着动态图| 国产午夜永久福利视频在线观看 | 亚洲 小说 欧美 另类 社区| 伊人久久大香线蕉无码| 国产乱码精品一品二品| 国产三级在线观看免费| 久久超碰极品视觉盛宴| 人妻av中文字幕久久| 国产人澡人澡澡澡人碰视频| 久久久久久99av无码免费网站| 欧美大波少妇在厨房被| 中文无码伦av中文字幕| 男人撕开奶罩揉吮奶头视频| 上司人妻互换hd无码| 男女爽爽无遮挡午夜视频| 国产又粗又猛又大爽又黄| 国产在线观看无码的免费网站 | 精品国产制服丝袜高跟| 疯狂做受xxxx高潮欧美日本| 国产超碰女人任你爽| 已婚少妇美妙人妻系列| 国产成人亚洲综合无码精品| 人妻精品制服丝袜久久久| 久久亚洲精品无码av红樱桃| 亚洲夂夂婷婷色拍ww47| 精品国产综合区久久久久久| 久久精品亚洲精品无码白云tv| 欧洲无码一区二区三区在线观看| 我的公把我弄高潮了视频| 国内熟妇人妻色在线视频| 免费国产午夜视频在线| 日产中文字幕在线观看| 国产美女视频免费观看的网站| 2021精品国产自在现线看| 成人天堂资源www在线| 国产成人无码av在线影院| 图片区小说区另类春色|