在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Protein arginine N-methyltransferase 6 (Prmt6)

Recombinant Mouse Protein arginine N-methyltransferase 6 (Prmt6)

  • 中文名稱：
    小鼠Prmt6重組蛋白
  • 貨號：
    CSB-YP747381MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Prmt6重組蛋白
  • 貨號：
    CSB-EP747381MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Prmt6重組蛋白
  • 貨號：
    CSB-EP747381MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Prmt6重組蛋白
  • 貨號：
    CSB-BP747381MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Prmt6重組蛋白
  • 貨號：
    CSB-MP747381MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Prmt6; Hrmt1l6Protein arginine N-methyltransferase 6; EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT6
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-378
  • 氨基酸序列
    MSLSKKRKLE SGDSGGAGAG GEGAEEENGG EQEAAPPRPR RTKSERDQLY YECYSDVSVH EEMIADQVRT EAYRLGILKN WAALRGKTVL DVGAGTGILS IFCAQAGARR VYAVEASAIW QQAREVVRLN GLEDRVHVLP GPVETVELPE RVDAIVSEWM GYGLLHESML SSVLHARTKW LKEGGLLLPA SAELFVAPIS DQMLEWRLGF WSQVKQHYGV DMSCMESFAT RCLMGHSEIV VQDLSGEDVL ARPQRFAQLE LARAGLEQEL EAGVGGRFRC SCYGSAPLHG FAVWFQVTFP GGDSEKPLVL STSPFHPATH WKQALLYLNE PVPVEQDTDI SGEITLLPSP DNPRRLRILL RYKVGDHEEK TKDFAMED
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Arginine methyltransferase that can catalyze the formation of both omega-N monomethylarginine (MMA) and asymmetrical dimethylarginine (aDMA), with a strong preference for the formation of aDMA. Preferentially methylates arginyl residues present in a glycine and arginine-rich domain and displays preference for monomethylated substrates. Specifically mediates the asymmetric dimethylation of histone H3 'Arg-2' to form H3R2me2a. H3R2me2a represents a specific tag for epigenetic transcriptional repression and is mutually exclusive with methylation on histone H3 'Lys-4' (H3K4me2 and H3K4me3). Acts as a transcriptional repressor of various genes such as HOXA2, THBS1 and TP53. Repression of TP53 blocks cellular senescence. Also methylates histone H2A and H4 'Arg-3' (H2AR3me and H4R3me, respectively). Acts as a regulator of DNA base excision during DNA repair by mediating the methylation of DNA polymerase beta (POLB), leading to the stimulation of its polymerase activity by enhancing DNA binding and processivity. Methylates HMGA1. Regulates alternative splicing events. Acts as a transcriptional coactivator of a number of steroid hormone receptors including ESR1, ESR2, PGR and NR3C1. Promotes fasting-induced transcriptional activation of the gluconeogenic program through methylation of the CRTC2 transcription coactivator. Methylates GPS2, protecting GPS2 from ubiquitination and degradation. Methylates SIRT7, inhibiting SIRT7 histone deacetylase activity and promoting mitochondria biogenesis.
  • 基因功能參考文獻：
    1. Six crystal structures of PRMT6 from Mus musculus, solved and refined at 1.34 A for the highest resolution structure are described. PMID: 26094878
    2. Prmt6 is important for embryonic stem cell pluripotency and self-renewal. PMID: 22455726
    3. The findings define a new regulator of p53 transcriptional regulation and define a role for PRMT6 and arginine methylation in cellular senescence. PMID: 22904064
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family, PRMT6 subfamily
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 人成午夜大片免费视频77777| 麻豆传传媒久久久爱| 久久人人爽人人爽人人片亞洲| 2012中文字幕在线视频| 国产在线一区二区在线视频| 人人超人人超碰超国产| 午夜精品一区二区三区免费视频| 国产99久一区二区三区a片| 日本一道本高清一区二区| 亚洲午夜福利精品无码不卡| 欧美不卡一区二区三区| 久久九九久精品国产| 中国china体内裑精亚洲日本| 亚洲久久久久久中文字幕| 失禁大喷潮在线播放| 亚洲精品无码mv在线观看| 男人吃奶摸下挵进去好爽| 欧美精品在线观看| 好男人社区资源| 99热亚洲色精品国产88| 国产69精品久久久久乱码韩国| 欧美三根一起进三p| 久久久天堂国产精品女人| 国产+日韩+另类+视频一区| 清纯唯美经典一区二区| 久久国产加勒比精品无码 | 无修无码h里番在线播放网站| 免费乱理伦片在线观看八戒| 亚洲精品国偷自产在线| 日本高清视频www夜色资源| 动漫精品无码h在线观看| 热久久视久久精品18| 亚洲国产精品无码一线岛国| 久久99精品国产自在现线小黄鸭| 国产亚洲色欲色一色www | 国产aⅴ夜夜欢一区二区三区| 国产亚洲精品a在线无码| 2020最新无码福利视频| 亚洲一区二区三区国产精品无码 | 樱花草在线社区www韩国| 精品av一区二区久久久|