在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Protein NLRC3 (Nlrc3), partial

Recombinant Mouse Protein NLRC3 (Nlrc3), partial

  • 中文名稱：
    小鼠Nlrc3重組蛋白
  • 貨號：
    CSB-YP691545MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nlrc3重組蛋白
  • 貨號：
    CSB-EP691545MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nlrc3重組蛋白
  • 貨號：
    CSB-EP691545MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nlrc3重組蛋白
  • 貨號：
    CSB-BP691545MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nlrc3重組蛋白
  • 貨號：
    CSB-MP691545MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nlrc3
  • Uniprot No.：
  • 別名：
    Nlrc3Protein NLRC3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Negative regulator of the innate immune response. Attenuates signaling pathways activated by Toll-like receptors (TLRs) and the DNA sensor STING/TMEM173 in response to pathogen-associated molecular patterns, such as intracellular poly(dA:dT), but not poly(I:C), or in response to DNA virus infection, including that of Herpes simplex virus 1 (HSV1). May affect TLR4 signaling by acting at the level of TRAF6 ubiquitination, decreasing the activating 'Lys-63'-linked ubiquitination and leaving unchanged the degradative 'Lys-48'-linked ubiquitination. Inhibits the PI3K-AKT-mTOR pathway possibly by directly interacting with the posphatidylinositol 3-kinase regulatory subunit p85 (PIK3R1/PIK3R2) and disrupting the association between PIK3R1/PIK3R2 and the catalytic subunit p110 (PIK3CA/PIK3CB/PIK3CD) and reducing PIK3R1/PIK3R2 activation. Via its regulation of the PI3K-AKT-mTOR pathway, controls cell proliferation, predominantly in intestinal epithelial cells. May also affect NOD1- or NOD2-mediated NF-kappa-B activation. Might also affect the inflammatory response by preventing NLRP3 inflammasome formation, CASP1 cleavage and IL1B maturation.
  • 基因功能參考文獻：
    1. NLRC3 promoted K48-linked polyubiquitination and degradation of interleukin-1 receptor-associated kinase 1 (IRAK1). PMID: 28731142
    2. NLRC3 inhibited Toll-like receptor (TLR)-dependent activation of the transcription factor NF-kappaB by interacting with the TLR signaling adaptor TRAF6 PMID: 22863753
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    NLRP family
  • 組織特異性：
    Expressed in bone marrow-derived macrophages.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲一区二区三区香蕉| 把插八插露脸对白内射| 国产真实夫妇视频| 欧美性猛交xxxx乱大交极品| 中文字幕乱码一区二区三区免费 | 国产乱人伦偷精品视频| 国产成+人+综合+亚洲欧美丁香花| 久久亚洲日韩av一区二区三区| 正在播放国产乱子伦最新视频| 国产9色在线 | 日韩| 樱花草在线社区www韩国| 韩国久久久久久级做爰片| 婷婷伊人五月尤物| 最新亚洲人成网站在线观看| 精品视频一区二区三三区四区 | 精品国产精品国产偷麻豆| 无码日本精品xxxxxxxxx| 最新国产久免费视频在线观看| 2020精品国产a不卡片| 韩国乱码伦视频免费| 粗大挺进尤物人妻中文字幕| 国产免费午夜福利在线播放11| 久久国产精品_国产精品| 国产超碰人人做人人爱ⅴa| 在线天堂www在线国语对白| 一区二区狠狠色丁香久久婷婷| 久久av无码精品人妻系列试探| 美女黄18以下禁止观看| 人人人爽人人爽人人av| 让少妇爽到高潮视频| 女女互磨互喷水高潮les呻吟| 久久免费午夜福利院| 宅宅午夜无码一区二区三区| 毛片免费视频在线观看| 美女av一区二区三区| 免费的av网站在线观看国产精品| 亚洲精品久久久久一区二区| 国产亚洲精品aaaa片app| 国产在热线精品视频99公交| 嫩草研究院久久久精品| 国产免费拔擦拔擦8x高清在线人|