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  4. Recombinant Mouse Protein ETHE1, mitochondrial (Ethe1)

Recombinant Mouse Protein ETHE1, mitochondrial (Ethe1)

  • 中文名稱：
    小鼠Ethe1重組蛋白
  • 貨號：
    CSB-YP861620MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ethe1重組蛋白
  • 貨號：
    CSB-EP861620MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ethe1重組蛋白
  • 貨號：
    CSB-EP861620MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ethe1重組蛋白
  • 貨號：
    CSB-BP861620MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ethe1重組蛋白
  • 貨號：
    CSB-MP861620MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ethe1
  • Uniprot No.：
  • 別名：
    Ethe1; HscoPersulfide dioxygenase ETHE1; mitochondrial; EC 1.13.11.18; Ethylmalonic encephalopathy protein 1 homolog; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    8-254
  • 氨基酸序列
    VAG RRLSQQSASG APVLLRQMFE PKSCTYTYLL GDRESREAVL IDPVLETAHR DAQLIKELGL KLLYAVNTHC HADHITGTGV LRSLLPGCQS VISRLSGAQA DLHIGEGDSI RFGRFALETR ASPGHTPGCV TFVLNDQSMA FTGDALLIRG CGRTDFQQGC AKTLYHSVHE KIFTLPGNCL IYPAHDYHGL TVSTVEEERT LNPRLTLSCE EFIKVMDNLN LPKPQQIDIA VPANMRCGVQ TPPS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    First described as a protein that can shuttle between the nucleus and the cytoplasm and suppress p53-induced apoptosis by sequestering the transcription factor RELA/NFKB3 in the cytoplasm and preventing its accumulation in the nucleus. Sulfur dioxygenase that plays an essential role in hydrogen sulfide catabolism in the mitochondrial matrix. Hydrogen sulfide (H(2)S) is first oxidized by SQRDL, giving rise to cysteine persulfide residues. ETHE1 consumes molecular oxygen to catalyze the oxidation of the persulfide, once it has been transferred to a thiophilic acceptor, such as glutathione (R-SSH). Plays an important role in metabolic homeostasis in mitochondria by metabolizing hydrogen sulfide and preventing the accumulation of supraphysiological H(2)S levels that have toxic effects, due to the inhibition of cytochrome c oxidase.
  • 基因功能參考文獻：
    1. Ethe1 deficiency disrupts post translational amino acid modification and mitochondrial metabolic systems. PMID: 23800285
  • 亞細胞定位：
    Cytoplasm. Nucleus. Mitochondrion matrix.
  • 蛋白家族：
    Metallo-beta-lactamase superfamily, Glyoxalase II family
  • 數據庫鏈接：


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