在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Prostaglandin E synthase 3 (Ptges3)

Recombinant Mouse Prostaglandin E synthase 3 (Ptges3)

  • 中文名稱：
    小鼠Ptges3重組蛋白
  • 貨號(hào)：
    CSB-YP879496MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ptges3重組蛋白
  • 貨號(hào)：
    CSB-EP879496MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ptges3重組蛋白
  • 貨號(hào)：
    CSB-EP879496MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ptges3重組蛋白
  • 貨號(hào)：
    CSB-BP879496MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ptges3重組蛋白
  • 貨號(hào)：
    CSB-MP879496MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Ptges3
  • Uniprot No.：
  • 別名：
    Ptges3; Sid3177; Tebp; Prostaglandin E synthase 3; EC 5.3.99.3; Cytosolic prostaglandin E2 synthase; cPGES; Hsp90 co-chaperone; Progesterone receptor complex p23; Sid 3177; Telomerase-binding protein p23
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-160
  • 氨基酸序列
    MQPASAKWYD RRDYVFIEFC VEDSKDVNVN FEKSKLTFSC LGGSDNFKHL NEIDLFHCID PNDSKHKRTD RSILCCLRKG ESGQSWPRLT KERAKLNWLS VDFNNWKDWE DDSDEDMSNF DRFSEMMDHM GGDEDVDLPE VDGADDDSQD SDDEKMPDLE
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.
  • 基因功能參考文獻(xiàn)：
    1. Skin differentiation is impaired, and both apoptosis and cell proliferation are augmented in the absence of p23; the consequences are a severe thinning of the stratum corneum and reduced numbers of hair follicles. Since the phenotype of p23-null embryos is strikingly similar to that of embryos lacking the glucocorticoid receptor, a paradigmatic Hsp90-p23 client protein, we investigated glucocorticoid signaling. PMID: 28650975
    2. Results identified two proteins P23 and HCLS1, which were not known as RNA-binding proteins, exhibiting RNA-binding activity. PMID: 27281784
    3. we report the generation of transgenic mouse lines that overexpress wild-type p23 or uncleavable p23 PMID: 23022695
    4. Data support a model in which p23 and GCN5 regulate diverse multistep pathways by controlling the longevity of protein-DNA complexes. PMID: 23022381
    5. p23 co-chaperone protects the aryl hydrocarbon receptor from degradation PMID: 22759865
    6. Cleavage product p19 was not seen in brain samples from a mouse model of Alzheimer disease, but p23 and p19 were seen in hypoxic cultured cells experienceing endoplasmic reticulum stress. PMID: 21691801
    7. In cytosol only one protein called p23 hsp90 binds to Bax but the binding protein does not affect the subcellular localization and pro-apoptotic activity of Bax. PMID: 22277657
    8. The p23 cochaperone of Hsp90, which plays a major role in glucocorticoid receptor folding and function, associates with influenza virus polymerase. PMID: 21853119
    9. Overexpression of p23 contributes to the development of hydronephrosis through the upregulation of the aryl hydrocarbon receptor pathway in vivo. PMID: 21323770
    10. prostaglandin E synthase (cPGES/p23) acts as a regulatory factor for expression of a PGE2-inactivating enzyme, 15-PGDH PMID: 21334450
    11. cPGES is required for glucocorticoid receptor function and embryonic growth but not dinoprostone biosynthesis. PMID: 17438133
    12. Embryos homozygous for cPGES/p23-null had lower body weights than wild-type embryos, and abnormal morphology of skin and lungs. PMID: 17719010

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    P23/wos2 family
  • 組織特異性：
    Expressed in testis, kidney, bladder and ovary.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产老妇伦国产熟女老妇视频| 少妇被粗大的猛进出69影院 | 熟妇丰满多毛的大隂户| 国产sm调教折磨视频| 亚洲日韩欧美一区二区三区在线| 国产69久久精品成人看| 久久性色欲av免费精品观看 | 白嫩少妇bbw撒尿视频| 好爽好硬好深高潮视频456| 国产后入又长又硬| 欧美性大战久久久久久| 国内大量揄拍人妻精品視頻| 亚洲日本在线在线看片| 黄床片30分钟免费视频教程| 国产精品videossex国产高清 | 国产精品久久久久久av福利| 中文字幕一区二区三区乱码| 在线视频免费观看爽爽爽| 成人免费b2b网站大全在线| 狠狠色色综合站| 国产精品国产三级国快看| 国产精品爆乳在线播放第一人称 | 伊人久久大香线蕉avapp下载| 亚洲精品综合一区二区三| 2019午夜福利不卡片在线| 黑人大荫蒂老太大| 久爱无码精品免费视频在线观看| 国产成人92精品午夜福利| 99精品日本二区留学生| 亚洲国产三级在线观看| 情侣黄网站免费看| 亚洲精品国精品久久99热| 欧美乱妇xxxxxbbbbb| 国产激情高中生呻吟视频| 久久久久成人精品免费播放动漫 | 国产高清av在线播放| 亚洲欧洲成人a∨在线观看| 香蕉视频在线精品视频| 国产一区二区女内射| 国产av大陆精品一区二区三区| 亚洲午夜精品a片一区二区app|