在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Prolyl endopeptidase (Prep)

  • 中文名稱:
    小鼠Prep重組蛋白
  • 貨號(hào):
    CSB-YP018664MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Prep重組蛋白
  • 貨號(hào):
    CSB-EP018664MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Prep重組蛋白
  • 貨號(hào):
    CSB-BP018664MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Prep重組蛋白
  • 貨號(hào):
    CSB-MP018664MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Prep; Pep; Prolyl endopeptidase; PE; EC 3.4.21.26; Post-proline cleaving enzyme
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    full length protein
  • 表達(dá)區(qū)域:
    1-710
  • 氨基酸序列
    MLSFQYPDVY RDETSVQEYH GHKICDPYSW LEDPDSEQTK AFVEAQNKIT VPFLEQCPIR GLYKERMTEL YDYPKYSCHF KKGKRYFYFY NTGLQNQRVL YVQDSLEGEA RVFLDPNTLS DDGTVALRGY AFSEDGEYFA YGLSASGSDW VTIKFMKVDG AKELPDVLER VKFTCMAWTH DGKGMFYNSY PQQDGKSDGT ETSTNLHQKL CYHVLGTDQS EDILCAEFPD EPKWMGGAEL SDDGRYVLLS IWEGCDPVNR LWYCDLQQEP NGITGILKWV KLIDNFEGEY DYVTNEGTVF TFKTNRNSPN YRLINIDFTD PDESKWKVLV PEHEKDVLEW VACVRSNFLV LCYLHDVKNI LQLHDLTTGA LLKTFPLDVG SVVGYSGRKK DSEIFYQFTS FLSPGVIYHC DLTKEELEPM VFREVTVKGI DAADYQTIQI FYPSKDGTKI PMFIVHKKGI KLDGSHPAFL YGYGGFNISI TPNYSVSRLI FVRHMGGVLA VANIRGGGEY GETWHKGGIL ANKQNCFDDF QCAAEYLIKE GYTSPKRLTI NGGSNGGLLV AACANQRPDL FGCVIAQVGV MDMLKFHKFT IGHAWTTDYG CSDTKQHFEW LLKYSPLHNV KLPEADDIQY PSMLLLTADH DDRVVPLHSL KFIATLQYIV GRSRKQSNPL LIHVDTKAGH GAGKPTAKVI EEVSDMFAFI ARCLNIEWIQ
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Cleaves peptide bonds on the C-terminal side of prolyl residues within peptides that are up to approximately 30 amino acids long.
  • 基因功能參考文獻(xiàn):
    1. PREP regulates the function of dopamine transporter, possibly by controlling the phosphorylation and transport of dopamine transporter into the striatum or synaptic membrane. PMID: 27966077
    2. Taken together, these data suggest that PREP can enhance alpha-synuclein toxicity in vivo. PMID: 29367610
    3. involved in trophoblast stem cell differentiation in placenta PMID: 28487025
    4. These findings might be explained as possible alteration in brain plasticity caused by PREP deficiency, which in turn affect behaviour and brain development PMID: 26996375
    5. Lung ischemia-reperfusion injury causes a dysregulation of circulating Ang 2 levels and plasma PREP activity, although no direct link between both phenomena could be shown. PMID: 27437782
    6. TLR4 activation releases prolyl endopeptidase containing exosomes from airway epithelial cells. PMID: 26222144
    7. the expression of prolyl endopeptidase could be necessary for a correct reproductive function PMID: 26332268
    8. As PREP inhibition also enhances autophagic clearance of aSyn, PREP inhibitors may reduce accumulation of aSyn inclusions via a dual mechanism and are thus a novel therapeutic candidate for synucleinopathies. PMID: 25555914
    9. lncPrep+96kb could play a role in the POP gene activation in the granulosa cell. PMID: 24369296
    10. PREP knockdown mice (Prep(gt/gt)) exhibited glucose intolerance, decreased fasting insulin, increased fasting glucagon levels, and reduced glucose-induced insulin secretion compared with wild-type controls. PMID: 25071172
    11. The study reveals a role for prolyl endopeptidase in mediating hippocampal plasticity and spatial memory formation. PMID: 22767632
    12. The POP promoter was sufficient for the appropriate localization in the placenta if it was not subject to position effect. PMID: 23632239
    13. the cytoplasmic and membrane-associated POP have distinct roles in different types of placental cells. PMID: 21544597
    14. Cigarette smoke-induced lung emphysema is associated with prolyl endopeptidase, an enzyme involved in collagen breakdown. PMID: 21112944
    15. in vitro reporter analysis indicated that CGI-2 enhanced POP promoter activity and its effect was significantly reduced by DNA methylation PMID: 20600704
    16. Murine T cells expressing high activity of prolyl endopeptidase are susceptible to activation-induced cell death. PMID: 11852073
    17. Report distribution of prolyl oligopeptidase in the mouse whole-body sections and peripheral tissues. PMID: 18618130
    18. peptidase activity is not required for PO function in neurons and suggest that PO instead acts by binding to cytosolic proteins that control growth cone and synaptic function. PMID: 19332125

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm.
  • 蛋白家族:
    Peptidase S9A family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 午夜爱爱免费视频体验区| 丰满岳跪趴高撅肥臀尤物在线观看| 国产精品成人永久在线四虎| 一道精品视频一区二区三区| 国产精品一区二区av蜜芽| 一区二区狠狠色丁香久久婷婷| 久久精品人妻中文系列| 伊人久久大香线蕉亚洲五月天| 国产精品兄妹在线观看麻豆| 欧美精品欧美人与动人物牲交| 天堂av色综合久久天堂| 99热在线精品国产观看| 少妇人妻偷人精品视频| 99国产精品白浆在线观看免费| 东京热一精品无码av| 四十如虎的丰满熟妇啪啪| 国产无遮挡又黄又爽不要vip软件 免费的av网站手机版 | 日本孕妇潮喷高潮视频| 中文字幕久久精品一区二区三区| 无码一区二区三区久久精品| 疯狂撞击丝袜人妻| 无码人妻丰满熟妇区毛片18| 美女粉嫩饱满的一线天mp4| av片在线观看永久免费| 抽插丰满内射高潮视频| 国产成av人片在线观看天堂无码| 欧美自拍亚洲综合丝袜| 亚洲男人的天堂av手机在线观看| 国产精品亚洲专区无码牛牛| 日本妇人成熟免费视频| 国产精品久久久久电影网| 欧美日本韩国亚洲| 人人妻人人添人人爽欧美一区| 亚洲免费人成视频观看| 麻豆国产成人av高清在线观看| 欧美黑人又粗又大又爽免费| 中文幕无线码中文字夫妻| 国精品人妻无码一区二区三区蜜柚| 亚洲一区二区三区含羞草| 久久久久人妻精品一区蜜桃| 亚洲熟妇另类久久久久久|