在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Usp9x), partial

Recombinant Mouse Probable ubiquitin carboxyl-terminal hydrolase FAF-X (Usp9x), partial

  • 中文名稱：
    小鼠Usp9x重組蛋白
  • 貨號：
    CSB-YP025754MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Usp9x重組蛋白
  • 貨號：
    CSB-EP025754MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Usp9x重組蛋白
  • 貨號：
    CSB-EP025754MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Usp9x重組蛋白
  • 貨號：
    CSB-BP025754MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Usp9x重組蛋白
  • 貨號：
    CSB-MP025754MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Usp9x; Fafl; Fam; Probable ubiquitin carboxyl-terminal hydrolase FAF-X; EC 3.4.19.12; Deubiquitinating enzyme FAF-X; Fat facets homolog; Fat facets protein-related; X-linked; Ubiquitin carboxyl-terminal hydrolase FAM; Ubiquitin thioesterase FAF-X; Ubiquitin-specific protease 9; X chromosome; Ubiquitin-specific-processing protease FAF-X
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Deubiquitinase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. May therefore play an important regulatory role at the level of protein turnover by preventing degradation of proteins through the removal of conjugated ubiquitin. Specifically hydrolyzes 'Lys-48'-, 'Lys-29'- and 'Lys-33'-linked polyubiquitins chains. Essential component of TGF-beta/BMP signaling cascade. Specifically deubiquitinates monoubiquitinated SMAD4, opposing the activity of E3 ubiquitin-protein ligase TRIM33. Deubiquitinates alkylation repair enzyme ALKBH3. OTUD4 recruits USP7 and USP9X to stabilize ALKBH3, thereby promoting the repair of alkylated DNA lesions. Regulates chromosome alignment and segregation in mitosis by regulating the localization of BIRC5/survivin to mitotic centromeres. Involved in axonal growth and neuronal cell migration. Regulates cellular clock function by enhancing the protein stability and transcriptional activity of the core circadian protein ARNTL/BMAL1 via its deubiquitinating activity.
  • 基因功能參考文獻：
    1. Study shows that USP9X deubiquitylating enzyme maintains RAPTOR protein levels, mTORC1 signalling and proliferation in neural progenitors. USP9X is the first deubiquitylating enzyme shown to stabilize RAPTOR. PMID: 28341829
    2. Report crucial role of the spermatogonial USP9X during transition from the mitotic to meiotic phases and/or maintenance of early meiotic phase in spermatogenesis. PMID: 28559472
    3. these findings highlight the critical role played by USP9X in the normal morphological development of the postnatal dentate gyrus. PMID: 27181636
    4. these data suggest that TCR-mediated signals enhance Themis stability upon T cell development and identify USP9X as a key regulator of Themis protein turnover PMID: 28877990
    5. In B lymphocytes, Usp9X is required for the induction of PKCbeta kinase activity after B-Cell Antigen Receptor-dependent activation. PMID: 26936881
    6. Usp9X is a positive regulator of proximal TCR signaling in peripheral T cells and also contributes to T cell tolerance established during intrathymic development. PMID: 25200027
    7. we identified USP9X as a potential therapeutic target in prostate cancer cells and established WP1130 as a lead compound for the development of ERG-depleting drugs. PMID: 24591637
    8. Loss of Usp9x disrupts cortical architecture, hippocampal development and TGFbeta-mediated axonogenesis. PMID: 23861879
    9. USP9X is a crucial positive regulator of the T Cell Receptor signaling pathway and is required for T-cell function through the modulation of Carma1-Bcl10-Malt1 complex formation. PMID: 23690623
    10. the deubiquitinase USP9X as a novel mTORC1 and -2 binding partner that negatively regulates mTOR activity and skeletal muscle differentiation. PMID: 22544753
    11. loss of Usp9x enhances transformation and protects pancreatic cancer cells from anoikis PMID: 22699621
    12. Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death. PMID: 21173155
    13. Expressed in both germ cell and supporting cell lineages during mouse gonadal development in stage- and sex-dependent manners. PMID: 12617843
    14. Usp9x is significantly higher in the adult female mouse brains than in male brains. This implies that the difference in sex chromosome complement between XY males and XX females could potentially contribute to sexual differentiation of brain structure. PMID: 15978012
    15. Age-associated changes in DNA methylation and ubiquitin system protein concentrations potentially contribute to developmental changes in brain structure and function. PMID: 16023255
    16. USP9X-induced polarization of neural progenitors results in their radial arrangement, which provides an environment conducive for self-renewal. PMID: 19176755

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cell projection, growth cone.
  • 蛋白家族：
    Peptidase C19 family
  • 組織特異性：
    Ubiquitously expressed in adult tissues.
  • 數據庫鏈接：


主站蜘蛛池模板： 日本少妇人妻xxxxx18| 成人国产一区二区三区| 国产精品爽爽v在线观看无码| 欧美激情内射喷水高潮| 欧美牲交a欧美牲交vdo18| 综合欧美日韩国产成人| 亚洲 日本 欧美 中文幕| 国产亚洲精品久久久久久牛牛| 麻豆久久久9性大片| 久久久久久成人综合网| 爆乳喷奶水无码正在播放| 无限看片在线版免费视频大全| 中文字幕无码中文字幕有码| 日本久久高清一区二区三区毛片| 18禁美女黄网站色大片在线| 中国少妇内射xxxhd免费| 久久综合伊人77777| 久久精品国产一区二区三区| 欧美乱妇xxxxxbbbbb| 嫩草研究院久久久精品| 国产中文字字幕乱码无限| 97免费公开在线视频| 久久久久99精品成人品| 精品精品国产高清a毛片| 久久婷婷色综合一区二区| 国产aⅴ精品一区二区三区尤物 | 国产精品亚洲成在人线| 久久毛片免费看一区二区三区| 欧美中日韩免费观看网站| 丰满少妇被猛烈进入高清播放| 国产成人片无码免费视频| 免费无码久久成人网站入口| 精品午夜福利无人区乱码一区| 高清精品一区二区三区| 香港曰本韩国三级网站| 日本精品高清一区二区| 久久精品久久电影免费理论片| 久久久精品妇女99| 性xxxx欧美老妇506070| 免费无码又爽又刺激高潮视频| 国产午夜精华2020在线|