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  4. Recombinant Mouse Pre-mRNA-splicing factor SPF27 (Bcas2)

Recombinant Mouse Pre-mRNA-splicing factor SPF27 (Bcas2)

  • 中文名稱：
    Recombinant Mouse Pre-mRNA-splicing factor SPF27(Bcas2)
  • 貨號：
    CSB-YP880479MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Pre-mRNA-splicing factor SPF27(Bcas2)
  • 貨號：
    CSB-EP880479MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Pre-mRNA-splicing factor SPF27(Bcas2)
  • 貨號：
    CSB-EP880479MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Pre-mRNA-splicing factor SPF27(Bcas2)
  • 貨號：
    CSB-BP880479MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Pre-mRNA-splicing factor SPF27(Bcas2)
  • 貨號：
    CSB-MP880479MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Bcas2
  • Uniprot No.：
  • 別名：
    Bcas2; Dam1; Pre-mRNA-splicing factor SPF27; Breast carcinoma-amplified sequence 2 homolog; DNA amplified in mammary carcinoma 1 protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-225
  • 氨基酸序列
    AGTGLVAGE VVVDALPYFD QGYEAPGVRE AAAALVEEET RRYRPTKNYL SYLTAPDYSA FETDIMRNEF ERLAARQPIE LLSMKRYELP APSSGQKNDI TAWQECVNNS MAQLEHQAVR IENLELMSQH GCNAWKVYNE NLVHMIEHAQ KELQKLRKHI QDLNWQRKNM QLTAGSKLRE MESNWVSLVS KNYEIERTIV QLENEIYQIK QQHGEANKEN IRQDF
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
  • 基因功能參考文獻：
    1. Study results suggest that Bcas2 regulates alternative splicing in spermatogonia and the transition to meiosis initiation, and male fertility. PMID: 28128212
    2. BCAS2 is an upstream regulator of beta-catenin gene expression and plays a role in dendrite growth at least partly through beta-catenin in the forebrain. PMID: 27713508
    3. BCAS2 interacts with HSF4 and negatively regulates its protein stability via ubiquitination. PMID: 26319152
    4. Maternal BCAS2 protects genomic integrity in mouse early embryonic development. PMID: 26428007
  • 亞細胞定位：
    Nucleus. Nucleus, nucleolus.
  • 蛋白家族：
    SPF27 family
  • 數據庫鏈接：


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