在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Potassium voltage-gated channel subfamily KQT member 4 (Kcnq4), partial

Recombinant Mouse Potassium voltage-gated channel subfamily KQT member 4 (Kcnq4), partial

  • 中文名稱：
    小鼠Kcnq4重組蛋白
  • 貨號：
    CSB-YP884939MO1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Kcnq4重組蛋白
  • 貨號：
    CSB-EP884939MO1
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Kcnq4重組蛋白
  • 貨號：
    CSB-EP884939MO1-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Kcnq4重組蛋白
  • 貨號：
    CSB-BP884939MO1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Kcnq4重組蛋白
  • 貨號：
    CSB-MP884939MO1
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Kcnq4
  • Uniprot No.：
  • 別名：
    Kcnq4; Potassium voltage-gated channel subfamily KQT member 4; KQT-like 4; Potassium channel subunit alpha KvLQT4; Voltage-gated potassium channel subunit Kv7.4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probably important in the regulation of neuronal excitability. May underlie a potassium current involved in regulating the excitability of sensory cells of the cochlea.
  • 基因功能參考文獻(xiàn)：
    1. we provide strong evidence that Kv7.4 channels are a key modulator of the excitability of VTA dopaminergic neurons, which contributes to the development of depressive behaviour PMID: 28885682
    2. is concluded that K(V)7 channels, via nifedipine sensitive channels, have a role in the regulation of basal renal vascular tone. PMID: 25965962
    3. Kv7.4 currents are inhibited in a CB1 pathway repressed by endocannabinoid 2-AG PMID: 24927567
    4. REST as a crucial transcriptional regulator for the Kv7.4 potassium channel subunit. PMID: 23242999
    5. analysis of the vestibular role of KCNQ4 and KCNQ5 K+ channels revealed by mouse models PMID: 23408425
    6. In 2 different rat and mouse models of hypertension, the functional impact of Kv7 channels was dramatically downregulated. PMID: 21747056
    7. Data show that in early pregnant mouse myometrium, the relative abundance of mRNA expression was KCNQ3 > KCNQ4 > KCNQ5 > KCNQ1 > KCNQ2. PMID: 20132415
    8. evidence of the cellular etiology and mechanisms of SGN degeneration in DFNA2. PMID: 20739290
    9. KCNQ channels set the resting membrane potential of inner hair cells in the isolated organ of Corti and maintain [Ca2+]i at low levels PMID: 12657673
    10. primary defect leading to high-frequency loss in DFNA2 patients may be attributable to high levels of the dysfunctional Kcnq4_v3 variant in the spiral ganglion and inner hair cells in the basal hook region PMID: 16207888
    11. Auditory function declined over several weeks in Kcnq4-/- mice and over several months in mice carrying the dominant negative allele. PMID: 16437162
    12. Analyses of vestibular hair cells (HCs) of Bdnf conditional mutant mice, which are devoid of any innervation, demonstrate that regulation of Kcnq4 expression in vestibular HCs is independent of innervation. PMID: 17292869
    13. Murine blood vessels exhibit a distinctive expression profile of KCNQ1, KCNQ4, and KCNQ5, with 'neuronal' KCNQ4 dominating PMID: 17519950
    14. variations within the C terminus of splice variants produce profound differences in the voltage-dependent phenotype and functional expression of the channel PMID: 17561493
    15. Results provide support for KCNQ4- or KCNQ5-encoded channels having an important functional impact in the vasculature. PMID: 18536747
    16. K(v)7.4 and K(v)7.5 are expressed in different regions of the murine gastrointestinal tract and blockers of K(v)7 channels augment inherent contractile activity. PMID: 19389803

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Basal cell membrane; Multi-pass membrane protein. Note=Situated at the basal membrane of cochlear outer hair cells.
  • 蛋白家族：
    Potassium channel family, KQT (TC 1.A.1.15) subfamily, Kv7.4/KCNQ4 sub-subfamily
  • 組織特異性：
    In the inner ear expressed in the outer sensory hair cells of the cochlea and in type I hair cells of the vestibular organs. Also expressed in the postsynaptic membrane of the calyx nerve endings innervating type I cells. In the brain expressed in neurons
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 香港经典a毛片免费观看hd| 久久99精品久久久久久水蜜桃| 我的公把我弄高潮了视频 | 又粗又硬又大又爽免费视频播放| 久久久久久久女国产乱让韩| 婷婷俺也去俺也去官网| 亚洲中文久久精品无码1| 国产婷婷色一区二区三区| 亚洲精品国产品国语在线观看| 午夜精品久久久久9999| 日韩精品无码去免费专区| 激情人妻另类人妻伦| 99精品国产在热久久无码| 国产清纯美女爆白浆视频| 欧美在线观看免费专区| 乱人伦人妻中文字幕无码久久网| 亚洲男人的天堂网站| 双乳被一左一右吃着动态图| 久久人人97超碰国产公开| 亚洲中文字幕无码爆乳| 成在人线av无码免观看麻豆| 香港三日本三级少妇三级2021| 茄子视频国产在线观看| 婷婷五月综合色视频| 亚洲级αv无码毛片久久精品| 日韩精品一区国产偷窥在线| 中国美女牲交视频| 国产成人精品日本亚洲第一区| 中文在线中文a| 日日摸日日碰夜夜爽亚洲综合| 96国产xxxx免费视频| 国产久热精品无码激情 | 欧美肥胖老妇bbw| 欧美极品video粗暴| 人成午夜免费大片| 国产精品亚洲综合色区韩国| 在线无码中文字幕一区| 久久www成人片免费看| 日韩a∨精品日韩在线观看| 韩国三级中文字幕hd久久精品 | 亚洲国产成人极品综合|