在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Polycomb group RING finger protein 6 (Pcgf6)

Recombinant Mouse Polycomb group RING finger protein 6 (Pcgf6)

  • 中文名稱：
    小鼠Pcgf6重組蛋白
  • 貨號：
    CSB-YP860407MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Pcgf6重組蛋白
  • 貨號：
    CSB-EP860407MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Pcgf6重組蛋白
  • 貨號：
    CSB-EP860407MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Pcgf6重組蛋白
  • 貨號：
    CSB-BP860407MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Pcgf6重組蛋白
  • 貨號：
    CSB-MP860407MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Pcgf6; Mblr; Rnf134; Polycomb group RING finger protein 6; Mel18 and Bmi1-like RING finger; RING finger protein 134
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-353
  • 氨基酸序列
    MDEAETDATE NKRASEAKRA SAMPPPPPPP PPISPPALIP APAAGEEGPA SLGQAGAAGC SRSRPPALEP ERSLGRLRGR FEDYDEELEE EEEMEEEEEE EEEMSHFSLR LESGRADSED EEERLINLVE LTPYILCSIC KGYLIDATTI TECLHTFCKS CIVRHFYYSN RCPKCNIVVH QTQPLYNIRL DRQLQDIVYK LVINLEEREK KQMHDFYKER GLEVPKPAAP QPVPSSKGKT KKVLESVFRI PPELDMSLLL EFIGANEDTG HFKPLEKKFV RVSGEATIGH VEKFLRRKMG LDPACQVDII CGDHLLERYQ TLREIRRAIG DTAMQDGLLV LHYGLVVSPL KIT
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    Transcriptional repressor. May modulate the levels of histone H3K4Me3 by activating KDM5D histone demethylase. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity.
  • 基因功能參考文獻(xiàn)：
    1. Pcgf6 acts as a master regulator to maintain embryonic stem cell identity. PMID: 27247273
    2. Conditional ablation of Pcgf6 in embryonic stem cells leads to robust de-repression of germ cell-related genes, in turn affecting cell growth and viability. PMID: 28304275
    3. The results identify two key regulators, PCGF6 and JARID1c that temper dendritic cells (DC) activation and implicate active transcriptional silencing via histone demethylation as a previously unappreciated mechanism for regulating DC activation and quiescence. PMID: 27498878
    4. Pcgf6 is essential for recruitment of PRC1.6 to chromatin. Our results reveal a previously uncharacterized, H2AK119ub1-independent chromatin assembly associated with PRC1.6 complex PMID: 28049731
    5. that Pcgf6 is nonredundantly involved in maintaining the pluripotent nature of embryonic stem cells and it functions in induced pluripotent stem reprogramming PMID: 25187489
    6. regulation by cell cycle-dependent phosphorylation PMID: 12167161

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in ovary, testis, stomach, liver, thymus and kidney (at protein level).
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 无码动漫性爽xo视频在线观看 | 国产美女被遭高潮免费视频 | 男生白内裤自慰gv白袜男同| 午夜dv内射一区二区| 丁香激情综合久久伊人久久| 色综合av综合无码综合网站| 欧美综合精品久久久久成人影院| 欧美另类 自拍 亚洲 图区| 国产suv精品一区二区33 | 精品无码av一区二区三区| 国产精品国产对白熟妇| 国产成人一区二区不卡免费视频| 天天躁日日躁狠狠躁av| 9420免费高清在线观看视频 | 99c视频色欲在线| 荫道bbwbbb高潮潮喷| 无码人妻aⅴ一区二区三区有奶水| 久久久久久人妻毛片a片| 国产人成无码视频在线1000| 国产精品婷婷久久爽一下| 国产午夜亚洲精品区| 国产精品国产自线拍免费不卡 | 内射女校花一区二区三区| 无码不卡av东京热毛片| 国产成人无码av在线影院| 国语自产精品视频在 视频| 久久久久无码精品国产| 国产艳妇av在线观看果冻传媒| 国产亚洲视频在线播放香蕉| 国产三级视频在线播放线观看| 综合亚洲伊人午夜网| 欧美午夜特黄aaaaaa片| 亚洲性视频免费视频网站| 国产v在线最新观看视频| 中国极品少妇xxxxx| 日韩人妻精品一区二区三区视频| 又色又爽又黄的视频女女| 肥臀熟女一区二区三区| 成年轻人电影www无码| 99在线 | 亚洲| 丰满人妻熟妇乱又仑精品|