在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Polycomb group RING finger protein 1 (Pcgf1)

Recombinant Mouse Polycomb group RING finger protein 1 (Pcgf1)

  • 中文名稱：
    小鼠Pcgf1重組蛋白
  • 貨號：
    CSB-YP854485MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Pcgf1重組蛋白
  • 貨號：
    CSB-EP854485MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Pcgf1重組蛋白
  • 貨號：
    CSB-EP854485MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Pcgf1重組蛋白
  • 貨號：
    CSB-BP854485MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Pcgf1重組蛋白
  • 貨號：
    CSB-MP854485MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Pcgf1; Nspc1; Rnf68; Polycomb group RING finger protein 1; Nervous system Polycomb-1; NSPc1; RING finger protein 68
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-259
  • 氨基酸序列
    ASPQGGQIA IAMRLRNQLQ SVYKMDPLRN EEEVRVKIKD LNEHIVCCLC AGYFVDATTI TECLHTFCKS CIVKYLQTSK YCPMCNIKIH ETQPLLNLKL DRVMQDIVYK LVPGLQDSEE KRIREFYQSR GLDRVSQPSG EEPALSNLGL PFSSFDHSKA HYYRYDEQLS LCLERLSSGK DKNKNVLQNK YVRCSVRAEV RHLRRVLCHR LMLNPQHVQL LFDNEVLPDH MTMKQLWLSR WFGKPSPLLL QYSVKEKRR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the Polycomb group (PcG) multiprotein BCOR complex, a complex required to maintain the transcriptionally repressive state of some genes, such as BCL6 and the cyclin-dependent kinase inhibitor, CDKN1A. Transcriptional repressor that may be targeted to the DNA by BCL6; this transcription repressor activity may be related to PKC signaling pathway. Represses CDKN1A expression by binding to its promoter, and this repression is dependent on the retinoic acid response element (RARE element). Promotes cell cycle progression and enhances cell proliferation as well. May have a positive role in tumor cell growth by down-regulating CDKN1A. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Regulates the expression of DPPA4 and NANOG in the NT2 embryonic carcinoma cells.
  • 基因功能參考文獻：
    1. Pcgf1 positively regulated expression of essential transcription factors involved in ectoderm and mesoderm differentiation, revealing an unexpected function of Pcgf1 in gene activation during ES cell lineage specification. PMID: 28393894
    2. Nspc1 has a positive role in maintaining the pluripotency of P19 cells by directly regulating Oct4. PMID: 24113379
    3. Pcgf1 is an epigenetic regulator of hematopoietic cell differentiation. Simultaneous depletion of Runx1 and Pcgf1 allows sustained self-renewal while blocking differentiation of lineage marker-negative cells in vitro. PMID: 22411870
  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：


主站蜘蛛池模板： 亚洲人禽杂交av片久久| 欧美老肥妇做爰bbww| 无码高潮又爽又黄a片软件| 精品视频国产狼友视频| 狠狠色噜噜狠狠狠狠色综合网| 亚洲成a人片在线观看无码专区| 午夜欧美精品久久久久久久| 精品无码中文字幕在线| 亚洲国产成人综合在线不卡| 国精产品蘑菇一区一区有限| 成人无码精品1区2区3区免费看| 久久无码av三级| 亚洲色婷婷婷婷五月基地| 色香阁综合无码国产在线| 亚洲色成人影院在线观看| 国产欧美在线观看不卡| 国产性生交xxxxx免费| 午夜美女裸体福利视频| 少妇无码av无码专区线y| 亚洲色成人www永久在线观看| 亚洲啪av永久无码精品放毛片| 国产精品亚洲精品日韩己满十八小| 久久国产精品国产四虎90后| 亚洲aⅴ无码专区在线观看q| 8x8ⅹ在线永久免费入口| 精品一卡二卡三卡| 午夜精品久久久久9999| 色欲天天婬色婬香综合网| 国产成人精品无码免费看夜聊软件 | 少妇高潮惨叫久久久久电影| 亚洲6080yy久久无码产自国产| 人妻 日韩 欧美 综合 制服| 国产精品亚洲成在人线| 国产av福利久久| 国产ww久久久久久久久久| 国产精品vⅰdeoxxxx国产| 国产成人片无码免费视频| 7777奇米成人狠狠成人影视| 成人毛片100部免费看| 另类 专区 欧美 制服| 97成人精品区在线播放|