在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Plexin-A1 (Plxna1), partial

Recombinant Mouse Plexin-A1 (Plxna1), partial

  • 中文名稱：
    小鼠Plxna1重組蛋白
  • 貨號：
    CSB-YP018217MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Plxna1重組蛋白
  • 貨號：
    CSB-EP018217MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Plxna1重組蛋白
  • 貨號：
    CSB-EP018217MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Plxna1重組蛋白
  • 貨號：
    CSB-BP018217MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Plxna1重組蛋白
  • 貨號：
    CSB-MP018217MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Plxna1; Kiaa4053; Plexin-A1; Plex 1; Plexin-1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
  • 基因功能參考文獻：
    1. species-dependent regulation of PlexA1 expression may have been crucial in the evolution of mammalian cortico-motoneuronal systems that improved fine motor control in higher primates. PMID: 28751609
    2. work reveals a 2-fold role of the PlxnA ectodomains: imposing a pre-signaling autoinhibitory separation for the cytoplasmic domains via intermolecular head-to-stalk interactions and supporting dimerization-based PlxnA activation upon ligand binding. PMID: 27397516
    3. PLXNA1 mediates the acquisition of malignant phenotypes induced by autocrine SEMA3A signaling in lung cancer cells. PMID: 27717823
    4. Study showed that progenitor cells lining the telencephalic ventricles express PlexinA1 and that absence of this receptor impairs neurogenesis in the developing forebrain PMID: 25975775
    5. PlexinA1 mediates both Semaphorin and Slit signaling PMID: 25485759
    6. genetic findings demonstrate that Sema3a repellent signaling plays a role in the establishment of proper afferent projections in SAG neurons, and this signaling likely occurs through a receptor complex involving Npn1 and either plexinA1 or plexinA3 PMID: 23991118
    7. A novel direct interaction between the Sema3a signaling receptor plexinA1 and nephrin, linking extracellular Sema3a signals to the slit-diaphragm signaling complex, was identified. PMID: 23954273
    8. These findings suggest a mechanism by which a complex of Sema6D, Nr-CAM, and Plexin-A1 at the chiasm midline alters the sign of Sema6D and signals Nr-CAM/Plexin-A1 receptors on retinal ganglion cells to implement the contralateral retinal cell projection. PMID: 22632726
    9. involved in the entry of dendritic cells into the lymphatics as a principal receptor for semaphorins PMID: 20512151
    10. Results suggest that plexin-A1 and B1 interact in the adult brain and transduce semaphorin 3A signaling in cooperation. PMID: 12559962
    11. Plexin-A1 affects t-cell-dendritic cell interaction but not antigen processing or binding. PMID: 12910265
    12. Plexin signaling uncouples cell substrate-adhesion from cytoskeletal dynamics required for cell migration and axon extension. PMID: 14734633
    13. Plexin-A1 forms a receptor complex with vascular endothelial growth factor receptor type 2 in heart morphogenesis PMID: 14977921
    14. During mouse embryogenesis, the murine ortholog of plexin-A1 gene showed restricted spatial and temporal expression in the hindbrain, consistent with a role in cell body movement, or axonal guidance during facial nerve development. PMID: 15996756
    15. plexin-A1 associates with the triggering receptor expressed on myeloid cells-2 (Trem-2), linking semaphorin-signalling to the immuno-receptor tyrosine-based activation motif (ITAM)-bearing adaptor protein, DAP12 PMID: 16715077
    16. our findings establish a role for plexin A1-mediated axonal exclusion in organizing the projection pattern of spinal sensory afferents PMID: 17145500
    17. There are distinct expression patterns of the individual plexin-A family members suggesting that regenerating rubrospinal and facial motoneurons have a differential ability to transduce semaphorin signals. PMID: 17197097

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    KEGG: mmu:18844

    STRING: 10090.ENSMUSP00000063066

    UniGene: Mm.3789



主站蜘蛛池模板： 女同性av片在线观看免费网站| 国产成人无码一区二区三区在线| 风韵丰满熟妇啪啪区老老熟妇 | 无尺码精品产品网站| 99久久国产露脸国语对白| 黑人猛挺进小莹的体内视频| 人妻无码vs中文字幕久久av爆| 国内极度色诱视频网站| 欧美人妻日韩精品| 精品国产综合成人亚洲区| 小雪好紧好滑好湿好爽视频| 麻豆专媒体一区二区| 国产真实伦在线观看| 麻豆精产国品| 永久黄网站免费视频性色| 99久久超碰中文字幕伊人| 搡老熟女国产| 国产内射合集颜射| 一本大道久久香蕉成人网| 8x国产精品视频| 成 人免费va视频| 无码专区—va亚洲v专区vr| 亚洲精品国产美女久久久99| 中文字幕av无码一区二区三区电影| 无码人妻精品一区二区蜜桃百度| 免费无码av片在线观看潮喷| 顶级欧美熟妇高潮xxxxx| 三个男吃我奶头一边一个视频| 无码人妻久久一区二区三区| 男女无遮挡猛进猛出免费观看视频| 浓毛欧美老妇乱子伦视频 | 97国语精品自产拍在线观看| 伊人久久亚洲综合影院首页| 欧美性xxxxx极品娇小| 免费无码a片一区二三区| 天下第一社区视频www日本| 亚洲 小说 欧美 激情 另类| 人人超碰人摸人爱| 欧美熟妇性xxxx交潮喷| 亚洲女同一区二区| 高潮又爽又无遮挡又免费|