在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Plasma serine protease inhibitor (Serpina5)

Recombinant Mouse Plasma serine protease inhibitor (Serpina5)

In Stock
  • 中文名稱：
    小鼠Serpina5重組蛋白
  • 貨號：
    CSB-BP021061MO
  • 規格：
    ￥3168
  • 圖片：
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他：

產品詳情

  • 純度：
    Greater than 90% as determined by SDS-PAGE.
  • 基因名：
  • Uniprot No.：
  • 別名：
    Serpina5; Pci; Plasma serine protease inhibitor; Plasminogen activator inhibitor 3; PAI-3; PAI3; Protein C inhibitor; PCI; Serpin A5
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 來源：
    Baculovirus
  • 分子量：
    45.3 kDa
  • 表達區域：
    25-405aa
  • 氨基酸序列
    SKKKKAKESSVGAVGPPSSKDFAFRLYRALVSESPGQNVFFSPLSVSMSLGMLSLGAGLKTKTQILDGLGLSLQQGQEDKLHKGFQQLLQRFRQPSDGLQLSLGSALFKDPAVHIRDDFLSAMKTLYMSDTFSTNFGNPEIAKKQINNYVAKQTKGKIVDFIKDLDSTHVMIVVNYIFFKAKWQTAFSETNTHKMDFHVTPKRTTQVPMMNREDGYSYYLDQNISCTVVGIPYQGNAIALFILPSEGKMKQVEDGLDERTLRNWLKMFTKRRLDLYLPKFSIEATYKLENVLPKLGIQDVFTTHADLSGITDHTNIKLSEMVHKSMMEVEESGTTAAAITGAIFTFRSARPSSLKIEFTRPFLLTLMEDSHILFVGKVTRP
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽：
    N-terminal 10xHis-tagged
  • 產品提供形式：
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液：
    Tris-based buffer,50% glycerol
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    3-7 business days
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Heparin-dependent serine protease inhibitor acting in body fluids and secretions. Inactivates serine proteases by binding irreversibly to their serine activation site. Involved in the regulation of intravascular and extravascular proteolytic activities. Plays hemostatic roles in the blood plasma. Acts as a procoagulant and proinflammatory factor by inhibiting the anticoagulant activated protein C factor as well as the generation of activated protein C factor by the thrombin/thrombomodulin complex. Acts as an anticoagulant factor by inhibiting blood coagulation factors like prothrombin, factor XI, factor Xa, plasma kallikrein and fibrinolytic enzymes such as tissue- and urinary-type plasminogen activators. In seminal plasma, inactivates several serine proteases implicated in the reproductive system. Inhibits the serpin acrosin; indirectly protects component of the male genital tract from being degraded by excessive released acrosin. Inhibits tissue- and urinary-type plasminogen activator, prostate-specific antigen and kallikrein activities; has a control on the sperm motility and fertilization. Inhibits the activated protein C-catalyzed degradation of SEMG1 and SEMG2; regulates the degradation of semenogelin during the process of transfer of spermatozoa from the male reproductive tract into the female tract. In urine, inhibits urinary-type plasminogen activator and kallikrein activities. Inactivates membrane-anchored serine proteases activities such as MPRSS7 and TMPRSS11E. Inhibits urinary-type plasminogen activator-dependent tumor cell invasion and metastasis. May also play a non-inhibitory role in seminal plasma and urine as a hydrophobic hormone carrier by its binding to retinoic acid.
  • 基因功能參考文獻：
    1. role of PCI not only for the function and/or maturation of macrophages, but also as a negative regulator of apoptotic cell and activated platelets removal PMID: 25000564
    2. The expression pattern of PCI throughout mouse development was mapped using in situ hybridization and immunohistochemistry. PMID: 20229239
    3. PCI exerts a procoagulant and proinflammatory effect by inhibiting APC PMID: 15140131
    4. In testes of wild type males PCI is detected in spermatocytes of prophase I, as well as in late spermatids and mature spermatozoa, but it is absent from somatic cells. PMID: 17434507
    5. The reactions with thrombin or APC of recombinant alpha(1)-PI M358R variants with or without the HCII extension were characterized electrophoretically and kinetically PMID: 18000606

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted, extracellular space.
  • 蛋白家族：
    Serpin family
  • 組織特異性：
    Not detected in blood plasma (at protein level). Expressed in testis, epididymis, seminal vesicles, prostate and ovaries.
  • 數據庫鏈接：


主站蜘蛛池模板： 强行无套内谢大学生初次| 国产在线国偷精品产拍| 国产伦精品免编号公布| 日产中文字幕在线观看| 老子影院午夜精品无码| 亚洲国产精品无码久久青草| 超碰色偷偷男人的天堂| 成 人 综合 亚洲另类| 天堂8а√中文在线官网| 国产亚洲日韩欧美另类丝瓜app| 四虎成人精品永久网站| 夜夜春夜夜爽| 亚洲精品国偷拍自产在线观看蜜臀| 国产精品一区二区在线观看| 98视频精品全部国产| 无码无套少妇18p在线直播 | 人人爽人人爽人人片a| 天天看片天天av免费观看| 少妇人妻久久无码专区| 无码任你躁久久久久久| 在线播放国产一区二区三区| 国产精品亚洲综合一区在线观看 | 国产成人免费永久播放视频平台 | 久久成人影院精品777| 99精品国产兔费观看久久| 国产午夜精华2020在线| 成人亚洲欧美丁香在线观看| 久久久久久av无码免费网站| 天堂在线观看www| 少妇一夜三次一区二区| 久久久久99精品成人品| 午夜dv内射一区二区| 凹凸国产熟女精品视频app| 狠狠综合亚洲综合亚洲色| 青青草国产免费国产是公开| 国产精品一区二区高清在线| 久久av无码αv高潮αv喷吹| 免费观看又色又爽又黄的韩国| 2020精品国产视| 精品一品国产午夜福利视频| 欧美激情猛片xxxⅹ大3|