在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Phosphoethanolamine/phosphocholine phosphatase (Phospho1)

Recombinant Mouse Phosphoethanolamine/phosphocholine phosphatase (Phospho1)

  • 中文名稱：
    小鼠Phospho1重組蛋白
  • 貨號：
    CSB-YP854501MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Phospho1重組蛋白
  • 貨號：
    CSB-EP854501MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Phospho1重組蛋白
  • 貨號：
    CSB-EP854501MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Phospho1重組蛋白
  • 貨號：
    CSB-BP854501MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Phospho1重組蛋白
  • 貨號：
    CSB-MP854501MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Phospho1
  • Uniprot No.：
  • 別名：
    Phospho1; Phosphoethanolamine/phosphocholine phosphatase; EC 3.1.3.75
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-267
  • 氨基酸序列
    MSGCFPAVGL RCLSRDGRMA APGAPRFLLT FDFDETIVDE NSDDSIVRAA PGQQLPESLR ATYREGYYNE YMQRVFKYLG EQGVRPRDLR AVYETIPLSP GMGDLLQFIA KQGSCFEVIL ISDANTFGVE SALRAAGHHS LFRRILSNPS GPDARGLLTL RPFHTHSCSR CPANMCKHKV LSEYLRERAR DGVHFERLFY VGDGANDFCP MGLLAGGDVA FPRRGYPMHR LIQEAQKAEP SSFRAHVVPW ETAADVRQHL QQVLKMC
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 668
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Phosphatase that has a high activity toward phosphoethanolamine (PEA) and phosphocholine (PCho). Involved in the generation of inorganic phosphate for bone mineralization. Acts in a non-redundant manner with PHOSPHO1 in skeletal mineralization: while PHOSPHO1 mediates the initiation of hydroxyapatite crystallization in the matrix vesicles (MVs), ALPL/TNAP catalyzes the spread of hydroxyapatite crystallization in the extracellular matrix.
  • 基因功能參考文獻：
    1. Osteoclastic resorption of the uncalcified matrix in Phospho1 KO mice was attenuated compared with surrounding normally mineralised bone PMID: 28737011
    2. These data support the involvement of phosphate transporter 1, hereafter referred to as Pi T-1, in the initiation of skeletal mineralization and provide compelling evidence that PHOSPHO1 function is involved in MV biogenesis PMID: 26773408
    3. role in mineralization of alveolar bone and cellular cementum PMID: 27016531
    4. Deficiency in PHOSPHO1 exerts modifications in bone architecture that are transient and depend upon age. PMID: 26232374
    5. ablation of the OPN gene, Spp1, leads to improvements in the skeletal phenotype in Phospho1(-/-) as they age PMID: 24825455
    6. mineralization abnormalities of dentin; reduced overall mineralization with decreased matrix vesicle mineralization in the Phospho1(-/-) mice; almost complete absence of matrix vesicles in mice; further reduction in mineralization. PMID: 23694930
    7. PHOSPHO1 plays a critical role in vascular smooth muscle cell mineralization. PMID: 22887744
    8. Phospho1(-/-) bones are hypomineralized and, consequently, are softer and more flexible. PMID: 21272676
    9. phospho1 has a role in initiation of skeletal calcification PMID: 20684022
    10. The lack of PHOSPHO1 affected ATP hydrolysis via a secondary reduction in the levels of TNAP in PHOSPHO1-deficient matrix vesicles. PMID: 19874193
    11. PHOSPHO1 localization is restricted to mineralizing regions of bone and growth plate PMID: 17227223

    顯示更多

    收起更多

  • 亞細胞定位：
    Extracellular vesicle.
  • 蛋白家族：
    HAD-like hydrolase superfamily, PHOSPHO family
  • 組織特異性：
    Has a 120-fold higher level of expression in bone compared with a range of soft tissues.
  • 數據庫鏈接：


主站蜘蛛池模板： av免费网站在线观看| 在线观看免费人成视频网| www内射国产在线观看| 亚洲精品国产av成拍色拍婷婷 | 欧美精品乱码99久久蜜桃| 午夜福利无遮挡十八禁视频| 久久99精品久久久久久久不卡| 蜜臀av免费一区二区三区| 国产精品免费一区二区三区四区| 成人午夜无码专区性视频性视频| 亚洲最大无码中文字幕网站| 国产在线视频www色| 日韩超碰人人爽人人做人人添 | 欧美亚洲国产片在线播放| 国产美女极度色诱视频www| 亚洲一区在线日韩在线秋葵| 中文字幕精品久久久久人妻红杏| 老头边吃奶边弄进去呻吟| 天堂√最新版中文在线地址| 午夜a理论片在线播放| 日韩一区二区三免费高清| 少妇无码太爽了不卡视频在线看| 久久天天躁夜夜躁狠狠躁2022| 老师黑色丝袜被躁翻了av| 四虎影库久免费视频| 无码日韩精品一区二区人妻| 麻豆国产va免费精品高清在线| 伊人久久大香线蕉aⅴ色| 无码视频一区二区三区| 日本xxxx裸体xxxx视频大全| 国产精品亚洲色婷婷99久久精品 | 日本老妇人乱xxy| 亚洲免费综合色在线视频| 亚洲日本va中文字幕亚洲| 国产精品美女久久久网av| 国产白浆喷水在线视频| 国语少妇高潮对白在线| 无码人妻aⅴ一区二区三区| 国产精品怡红院在线观看| 精品熟女少妇av久久免费软件 | 国产美足白丝榨精在线观看sm|