在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse PDZ and LIM domain protein 2 (Pdlim2)

Recombinant Mouse PDZ and LIM domain protein 2 (Pdlim2)

  • 中文名稱：
    小鼠Pdlim2重組蛋白
  • 貨號：
    CSB-YP848100MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Pdlim2重組蛋白
  • 貨號：
    CSB-EP848100MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Pdlim2重組蛋白
  • 貨號：
    CSB-EP848100MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Pdlim2重組蛋白
  • 貨號：
    CSB-BP848100MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Pdlim2重組蛋白
  • 貨號：
    CSB-MP848100MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Pdlim2
  • Uniprot No.：
  • 別名：
    Pdlim2; PDZ and LIM domain protein 2; PDZ-LIM protein mystique
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區(qū)域：
    1-349
  • 氨基酸序列
    MALTVDVAGP APWGFRISGG RDFHTPIIVT KVTERGKAEA ADLRPGDIIV AINGQSAENM LHAEAQSKIR QSASPLRLQL DRSQTASPGQ TNGEGSLEVL ATRFQGSLRT HRDSQSSQRS ACFSPVSLSP RPCSPFSTPP PTSPVALSKE DMIGCSFQSL THSPGLAAAH HLTYPGHPTS QQAGHSSPSD SAVRVLLHSP GRPSSPRFSS LDLEEDSEVF KMLQENRQGR AAPRQSSSFR LLQEALEAEE RGGTPAFVPS SLSSQASLPT SRALATPPKL HTCEKCSVNI SNQAVRIQEG RYRHPGCYTC ADCGLNLKMR GHFWVGNELY CEKHARQRYS MPGTLNSRA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Probable adapter protein located at the actin cytoskeleton that promotes cell attachment. Necessary for the migratory capacity of epithelial cells. Overexpression enhances cell adhesion to collagen and fibronectin and suppresses anchorage independent growth. May contribute to tumor cell migratory capacity.
  • 基因功能參考文獻：
    1. Reducing NF-kappaB activation attenuates PDLIM2 deficiency-exacerbated inflammation and dyslipidemia in Palmitate -treated primary hepatocytes. PMID: 29852170
    2. Klotho can modulate inflammation via PDLIM2/NF-kappaB p65 pathway in cyclosporine A-induced nephropathy. PMID: 28315683
    3. Deficiency in PDLIM2 resulted in the accumulation of STAT3 in the nucleus, enhanced the extent of TH17 cell differentiation, and exacerbated granuloma formation. PMID: 22155789
    4. Pdlim2 is a novel actin-regulating protein of podocyte foot processes that may have a role in the pathogenesis of glomerular diseases. PMID: 21814175
    5. PDLIM2 expression was sufficient to suppress in vitro anchorage-independent growth and in vivo tumor formation of colon cancer. PDLIM2 repression involves promoter methylation. PMID: 20145149
    6. Knockdown of Mystique 2 with small interfering RNA abrogated both adhesion and migration in MCF10A and MCF-7 cells PMID: 15659642
    7. SLIM is a novel ubiquitin E3 ligase whose targets include STAT proteins. PMID: 15963787
    8. PDLIM2 deficiency resulted in larger amounts of nuclear p65, defective p65 ubiquitination and augmented production of proinflammatory cytokines in response to innate stimuli PMID: 17468759
    9. Stat-interacting LIM protein as the critical Stat ubiquitin E3 ligase involved in osteopontin regulation of Stat1. PMID: 17898865
    10. Suppression of PDLIM2 expression resulted in decreased cell adhesion, increased NF-kappaB transcription reporter activity, and increased LPS-induced TNF-alpha production. PMID: 19052146

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Cytoplasm, cytoskeleton.
  • 組織特異性：
    Highly expressed in lung. Expressed at intermediate level in kidney, testis and spleen. Weakly expressed in heart and brain.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 国产免费毛卡片| 国产精品美女久久久久| 成人性生交大片免费看中文| 日韩一区二区三区精品| 一本久道高清无码视频| 特黄做受又粗又长又大又硬| 日韩做a爰片久久毛片a片| 大地资源在线观看官网第三页| 激情综合婷婷色五月蜜桃| 精品欧美乱码久久久久久1区2区 | 影音先锋啪啪av资源网站| 豆国产95在线 | 亚洲| 国产爆乳无码一区二区麻豆| 久久久久无码精品国产人妻无码| 国产免费二卡3卡四卡| 久久无码专区国产精品| 国产麻豆剧传媒精品av| 国产免费啪嗒啪嗒视频看看| 成人黄网站高清免费视频| 国产亚洲精品精品国产亚洲综合| 国产肥熟女视频一区二区三区| 亚洲精品欧美综合一区二区 | 噜噜久久噜噜久久鬼88| 好吊妞视频这里有精品| aaa少妇高潮大片免费看| 国产精品久久久久久爽爽爽床戏| 久久综合给合久久97色| 国产精品欧美一区二区三区不卡| 亚洲人成电影网站色| 国产精品va在线观看老妇女| 国产精品福利自产拍久久| 日本高清无卡码一区二区久久| 无码中文字幕av免费放| 亚洲精品久久久久久动漫| 级r片内射在线视频播放| 亚洲国产成人精品无码区在线秒播 | 久久精品人妻无码专区| 国产激情精品一区二区三区| 亚洲动漫精品无码av天堂| 国产成人av综合久久视色| 国产极品粉嫩泬免费观看|