在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Ornithine transcarbamylase, mitochondrial (Otc)

Recombinant Mouse Ornithine transcarbamylase, mitochondrial (Otc)

  • 中文名稱：
    小鼠Otc重組蛋白
  • 貨號(hào)：
    CSB-YP017270MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Otc重組蛋白
  • 貨號(hào)：
    CSB-EP017270MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Otc重組蛋白
  • 貨號(hào)：
    CSB-BP017270MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Otc重組蛋白
  • 貨號(hào)：
    CSB-MP017270MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Otc; Ornithine carbamoyltransferase; mitochondrial; EC 2.1.3.3; Ornithine transcarbamylase; OTCase
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    33-354
  • 氨基酸序列
    SQVQLKGR DLLTLKNFTG EEIQYMLWLS ADLKFRIKQK GEYLPLLQGK SLGMIFEKRS TRTRLSTETG FALLGGHPSF LTTQDIHLGV NESLTDTARV LSSMTDAVLA RVYKQSDLDT LAKEASIPIV NGLSDLYHPI QILADYLTLQ EHYGSLKGLT LSWIGDGNNI LHSIMMSAAK FGMHLQAATP KGYEPDPNIV KLAEQYAKEN GTKLSMTNDP LEAARGGNVL ITDTWISMGQ EDEKKKRLQA FQGYQVTMKT AKVAASDWTF LHCLPRKPEE VDDEVFYSPR SLVFPEAENR KWTIMAVMVS LLTDYSPVLQ KPKF
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes the second step of the urea cycle, the condensation of carbamoyl phosphate with L-ornithine to form L-citrulline. The urea cycle ensures the detoxification of ammonia by converting it to urea for excretion.
  • 基因功能參考文獻(xiàn)：
    1. Gene correction in adult OTC-deficient mice was lower and accompanied by larger deletions that ablated residual expression from the endogenous OTC gene, leading to diminished protein tolerance and lethal hyperammonemia on a chow diet PMID: 26829317
    2. The corresponding OTC tissue enzyme activities were between 3-6% of normal control in mouse and human liver. The use of the cryptic splice sites was reproduced in minigenes carrying murine or human mutant sequences PMID: 25853564
    3. Serum OCT seemed to reflect tumor necrosis factor-alpha-mediated hepatic damage in diabetic obese mice and could be useful in the application for non-alcoholic fatty liver disease with features of metabolic syndrome, such as obesity and diabetes. PMID: 19793175
    4. in vivo regulation by HNF4alpha PMID: 11994307
    5. Results highlight the importance of the interaction between the OTC spf-ash mutation (ornithine transcarbamylase deficiency) and genetic backgrounds on metabolic phenotypes (ureagenesis, arginine metabolism, and nitric oxide production). PMID: 17925451
    6. Phenotypic correction of OTC deficiency using low-dose helper-dependent adenoviral vectors is reported. PMID: 18563850
    7. Lysine 88 acetylation negatively regulates ornithine carbamoyltransferase activity in response to nutrient signals. PMID: 19318352

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Defects in Otc are the cause of the Sparse fur (spf) phenotype. Spf mouse have an OTCase with an overall decrease in activity, and altered substrate affinity.
  • 亞細(xì)胞定位：
    Mitochondrion matrix.
  • 蛋白家族：
    ATCase/OTCase family
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲国产av无码综合原创国产| 日本肉体xxxx裸体137大胆| 久久综合九色综合97网| 狠狠色婷婷久久综合频道日韩| 丁香五月婷激情综合第九色| 国产综合有码无码中文字幕| 亚洲欧美日韩综合av| 欧美熟妇性xxx交潮喷| 婷婷成人综合激情在线视频播放| 国产熟睡乱子伦午夜视频| 国产做爰xxxⅹ高潮视频12p| 秋霞国产精品一区二区| 中文字幕人成人乱码亚洲电影| 夜夜爽妓女8888视频免费观看| 国产乱子伦三级在线播放| 人妻老妇乱子伦精品无码专区| 极品新婚夜少妇真紧| 亚洲综合无码一区二区三区| 一本大道一卡2卡三卡4卡国产| aaa午夜级特黄日本大片| 熟妇人妻无乱码中文字幕| 国产成人欧美综合在线影院| 天天看片视频免费观看| 亚洲a片成人无码久久精品色欲 | 国产精品国产午夜免费看福利| 噜噜高清欧美内射短视频| 国产成人精品一区二区三区视频| 免费国产a国产片高清网站| 美女黄频视频大全免费的国内| 伊人久久大香线蕉成人| 真实国产老熟女无套中出| 人人玩人人添人人澡超碰偷拍 | 日本xxxx18野外无毒不卡| 国产精品视频永久免费播放| 国产精品a成v人在线播放| 亚洲国产美国国产综合一区| 日本免费高清一本视频| 亚洲伊人久久综合影院| 内射巨臀欧美在线视频| 在线观看片免费人成视频无码| 中文字幕乱码人妻无码久久|