在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Orexin receptor type 2 (Hcrtr2), partial

Recombinant Mouse Orexin receptor type 2 (Hcrtr2), partial

  • 中文名稱：
    小鼠Hcrtr2重組蛋白
  • 貨號：
    CSB-YP010232MO1
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Hcrtr2重組蛋白
  • 貨號：
    CSB-EP010232MO1
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Hcrtr2重組蛋白
  • 貨號：
    CSB-EP010232MO1-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Hcrtr2重組蛋白
  • 貨號：
    CSB-BP010232MO1
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Hcrtr2重組蛋白
  • 貨號：
    CSB-MP010232MO1
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Hcrtr2; Mox2r; Orexin receptor type 2; Ox-2-R; Ox2-R; Ox2R; Hypocretin receptor type 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Nonselective, high-affinity receptor for both orexin-A and orexin-B neuropeptides. Triggers an increase in cytoplasmic Ca(2+) levels in response to orexin-A binding.
  • 基因功能參考文獻：
    1. In an heart failure model, HCRTR2-deficient mice exhibited poorer cardiac function, worse treadmill exercise capacity, and greater myocardial scarring PMID: 26653627
    2. orexin activation of OX2R in the brain centrally enhances bone formation by lowing circulating leptin level. PMID: 24794976
    3. Knocking down the Orx2 receptors in the basolateral amygdala increased anxious behavior as measured by reduced social preference and reduced time spent in the center of an open field. PMID: 24485472
    4. OX2R activation induces PKC-mediated ERK and CREB phosphorylation. PMID: 22652455
    5. In the hypothalamus, the OX2 receptors have an inhibitory role in modulating basal concentrations of NE, ACh, and Hist. In the prefrontal cortex, the evoked release of the monoamines NE, 5-HT, and DA seems to be controlled negatively by OX2 receptors. PMID: 22038504
    6. Mice lacking OX2R signaling had poor maintenance of wakefulness indicative of sleepiness and fragmented sleep and lacked any electrophysiological response to orexin-A in the wake-promoting neurons of the tuberomammillary nucleus. PMID: 21368172
    7. activation of orexin neurons through OX2R might have an important role in the maintenance of arousal. PMID: 20861370
    8. Regulation of sleep/wake states is completely achieved by OX(2)R-expressing neurones without involving H(1)R-mediated pathways. Maintenance of basal physiological sleep/wake states is fully achieved without both H(1) and OX(1) receptors. PMID: 19694625
    9. So, the SAF diet can alter adipocytic adiposity-related gene expression and result in effective amelioration of diet-induced obesity. PMID: 20213045
    10. hypocretin receptor 2 mRNA levels declined with age in the hippocampus, thalamus, pons, and medulla (hypocretin receptor 2) PMID: 12399012
    11. OX2alphaR is expressed in various areas of the mouse brain and has low expression in caudal part of cerebellum PMID: 16806113
    12. The enhanced orexin-orexin receptor2 signaling confers resistance to diet-induced features of the metabolic syndrome through negative energy homeostasis and improved leptin sensitivity. PMID: 19117547
    13. Biochemical and behavioural characterization of EMPA, a novel high-affinity, selective antagonist for the OX(2) receptor. PMID: 19751316

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Multi-pass membrane protein.
  • 蛋白家族：
    G-protein coupled receptor 1 family
  • 組織特異性：
    Widely expressed. Isoform 2 not detected in skeletal muscle and kidney.
  • 數據庫鏈接：


主站蜘蛛池模板： 产后漂亮奶水人妻无码| 日本丰满熟妇videossex| 国产精品无码av片在线观看播 | 高中国产开嫩苞实拍视频在线观看 | 无码大潮喷水在线观看| 久久精品噜噜噜成人av| 色偷偷亚洲男人本色| 国产精品久久久久久久久久久久午衣片 | 国产成人亚洲高清一区| 少妇大胆瓣开下部自慰| 亚洲色一区二区三区四区| 女人被狂躁c到高潮| 国产精品午夜福利麻豆| 一本清日本在线视频精品| 免费观看又污又黄的网站| 精品国产sm最大网免费站 | 爆乳女仆高潮在线观看| 国产精品自在拍在线播放| 老司机在线精品视频网站| 亚洲国产无套无码av电影| 四虎成人精品在永久免费| а√8天堂中文官网资源| 国产沙发午睡系列999| 亚洲天天做日日做天天欢毛片| 最新高清无码专区| 51妺嘿嘿午夜福利| 无遮挡男女激烈动态图| 嫩草伊人久久精品少妇av| 无码成人一区二区三区| 国产精品亚洲w码日韩中文 | 国产男生夜间福利免费网站| 综合久久给合久久狠狠狠97色| 无码人妻精品中文字幕| 亚洲欧洲自拍拍偷精品 美利坚| 在线亚洲专区高清中文字幕| 真人二十三式性视频(动) | 亚洲日韩成人性av网站| 日韩精品专区在线影院重磅| 国产精品成人av在线观看| 野狼第一精品社区| 免费女上男下xx00xx00视频|