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  4. Recombinant Mouse Nuclear autoantigenic sperm protein (Nasp)

Recombinant Mouse Nuclear autoantigenic sperm protein (Nasp)

  • 中文名稱：
    小鼠Nasp重組蛋白
  • 貨號(hào)：
    CSB-YP857499MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nasp重組蛋白
  • 貨號(hào)：
    CSB-EP857499MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nasp重組蛋白
  • 貨號(hào)：
    CSB-EP857499MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nasp重組蛋白
  • 貨號(hào)：
    CSB-BP857499MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nasp重組蛋白
  • 貨號(hào)：
    CSB-MP857499MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nasp
  • Uniprot No.：
  • 別名：
    Nasp; Nuclear autoantigenic sperm protein; NASP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-773
  • 氨基酸序列
    ATESTAAAA IAAELVSADK IEDAPAPSTS ADKMESLDVD SEAKKLLGLG QKHLVMGDIP AAVNAFQEAA SLLGKKYGET ANECGEAFFF YGKSLLELAR MENGVLGNAL EGVHVEEEEG EKTEDESLVE NNDNVDEEAR EELREQVYDA MGEKEAKKAE GKSLTKPETD KEQESEVEKG GREDMDISEP EEKLQETVEP TSKQLTESSE EAKEAAIPGL NEDEVASGKT EQESLCTEKG KSISGAYVQN KEFRETVEEG EEIISLEKKP KETSEDQPIR AAEKQGTLMK VVEIEAEIDP QVKSADVGGE EPKDQVATSE SELGKAVLME LSGQDVEASP VVAAEAGAEV SEKPGQEITV IPNNGPVVGQ STVGDQTPSE PQTSAERLTE TKDGSSVEEV KAELVPEQEE AMLPVEESEA AGDGVETKVA QKATEKAPED KFKIAANEET PERDEQMKEG EETEGSEEED RENDKAEETP NESVLEKKSL QENEEEEIGN LELAWDMLDL AKIIFKRQET KEAQLYAAQA HLKLGEVSVE SENYIQAVEE FQACLSLQEQ YLEAHDRLLA ETHYQLGLAY GYNSQYDEAV AQFGKSIDVI EKRMAVLHEQ MKEAEGSFTE YEKEIEELKE LLPEIREKIE DAKESQRSGN VAELALKATL VESSTSGFTP SGAGASVSMI ASRKPTDGAS SSNCVTDISH LVRKKRKPEE ESPRKDDAKK AKQEPEVNGG SGDAVSSGKE VSENMEAEAE NQAESQTAEG TVESAATIKS TAC
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Required for DNA replication, normal cell cycle progression and cell proliferation. Forms a cytoplasmic complex with HSP90 and linker H1 histones and stimulates HSP90 ATPase activity. NASP and H1 histone are subsequently released from the complex and translocate to the nucleus where the histone is released for binding to DNA.
  • 基因功能參考文獻(xiàn)：
    1. an increase of miR-29a, and hence decrease of Nasp, may contribute to inhibit cell proliferation during postnatal organ development. PMID: 22194605
    2. NASP controls the ability of HSPA2 to activate CDC2 for CDC2/cyclin B1 complex formation; therefore, tNASP's role is to provide the functional link between linker histones and cell cycle progression during meiosis. PMID: 19553603
    3. overexpression affects progression through cell cycle PMID: 12509435
    4. in the cytoplasm linker histones are bound to a complex containing NASP and HSP90 whose ATPase activity is stimulated by binding NASP PMID: 15533935
    5. NASP and the linker histones are key players in the assembly of chromatin after DNA replication PMID: 16728391

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  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    NASP family
  • 組織特異性：
    Isoform 1 is found in gametes, embryonic cells and transformed cells. Isoform 2 is found in dividing somatic cells (at protein level).
  • 數(shù)據(jù)庫(kù)鏈接：


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