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  4. Recombinant Mouse Neuron-specific vesicular protein calcyon (Caly), partial

Recombinant Mouse Neuron-specific vesicular protein calcyon (Caly), partial

  • 中文名稱：
    Recombinant Mouse Neuron-specific vesicular protein calcyon(Caly),partial
  • 貨號：
    CSB-YP875282MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse Neuron-specific vesicular protein calcyon(Caly),partial
  • 貨號：
    CSB-EP875282MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse Neuron-specific vesicular protein calcyon(Caly),partial
  • 貨號：
    CSB-EP875282MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse Neuron-specific vesicular protein calcyon(Caly),partial
  • 貨號：
    CSB-BP875282MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse Neuron-specific vesicular protein calcyon(Caly),partial
  • 貨號：
    CSB-MP875282MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Caly
  • Uniprot No.：
  • 別名：
    Caly; Drd1ipNeuron-specific vesicular protein calcyon
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Interacts with clathrin light chain A and stimulates clathrin self-assembly and clathrin-mediated endocytosis.
  • 基因功能參考文獻：
    1. endocytic and cargo sorting functions of Caly in neurons PMID: 28734834
    2. The data of this study suggested that calcyon directly interacts with mu3A and mu3B, and regulates the subcellular distribution of AP-3 and the targeting of AP-3 cargoes. PMID: 22650988
    3. The resultd of this study showed that with calcyon-overexpressing Cal(OE) transgenic mice that lifelong calcyon upregulation impairs executive functions including response inhibition and working memory. PMID: 21403673
    4. Transgenic mice display a range of abnormal behaviors including spontaneous hyperactivity, reduced anxiety, and/or impaired restraint (harm avoidance) that would indicate that calcyon up-regulation leads to deficits in control over behavioral output. PMID: 18295356
    5. Taken together, the present studies involving biochemical, immunological and electrophysiological analyses raise the possibility that calcyon plays a specialized role in regulating activity-dependent removal of synaptic AMPARs. PMID: 19120439

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  • 亞細胞定位：
    Cytoplasmic vesicle membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein.
  • 蛋白家族：
    NSG family
  • 組織特異性：
    Most abundant in brain. Also expressed in testis and ovary and, at much lower levels, in kidney and heart.
  • 數據庫鏈接：


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