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  4. Recombinant Mouse NGFI-A-binding protein 1 (Nab1)

Recombinant Mouse NGFI-A-binding protein 1 (Nab1)

  • 中文名稱：
    小鼠Nab1重組蛋白
  • 貨號：
    CSB-YP726736MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nab1重組蛋白
  • 貨號：
    CSB-EP726736MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nab1重組蛋白
  • 貨號：
    CSB-EP726736MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nab1重組蛋白
  • 貨號：
    CSB-BP726736MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nab1重組蛋白
  • 貨號：
    CSB-MP726736MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nab1
  • Uniprot No.：
  • 別名：
    Nab1; NGFI-A-binding protein 1; EGR-1-binding protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-486
  • 氨基酸序列
    MATALPRTLG ELQLYRILQK ANLLSYFDAF IQQGGDDVQQ LCEAGEEEFL EIMALVGMAS KPLHVRRLQK ALRDWVTNPG LFNQPLTSLP VSSIPIYKLP EGSPTWLGIS CNSYERSSSS REPHLKIPKC AATTCVQSLG QGKSEVGSLA LQSVSDSRLW QGHHATESEH SLSPADLGSP ASPKESSEAL DAAAALSVAE CVERMAPTLP KSDLSEVKEL LKNNKKLAKM IGHIFEMSDE DPHKEEEIRK YSAIYGRFDS KRKDGKHLTL HELTVNEAAA QLCVKDNALL TRRDELFALA RQVSREVTYK YTYRTTRLKC GERDELSPKR IKIEDGFPDF QESVPTLFQQ ARAKSEELAG LGSQQAEKGM AKQMELLCAQ AGYERLQQER RLTAGLYRQS SGEQSPDGGL PSDSSDGQGE RPLNLRIPSV QNRQPHHFVV DGELSRLYSS EAKSHSSESL GILKDYPHSA FTLEKKVIKT EPEDSR
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a transcriptional repressor for zinc finger transcription factors EGR1 and EGR2.
  • 基因功能參考文獻：
    1. These data suggest that type I IFN stimulation induces a rapid recruitment of a repressive Egr3/Nab1 complex that silences transcription from the ifngr1 promoter. PMID: 23935197
    2. Nab1 is a potent inhibitor of cardiac growth in response to pathological stimuli in vivo. PMID: 16025126
    3. Nab1 and Nab2 proteins are necessary for Schwann cells to exit the cell cycle, downregulate suppressed cAMP-inducible protein (SCIP) expression and upregulate expression of critical myelination genes. PMID: 16136673
    4. Egr2 directly represses genes during myelination in conjunction with NAB corepressors PMID: 18456662
  • 亞細胞定位：
    Nucleus.
  • 蛋白家族：
    NAB family
  • 組織特異性：
    Widely expressed in adult. In day 16 embryo highest levels in forebrain, thymus, salivary gland and cartilage.
  • 數據庫鏈接：


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