在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Mediator of RNA polymerase II transcription subunit 12 (Med12), partial

  • 中文名稱:
    小鼠Med12重組蛋白
  • 貨號(hào):
    CSB-YP013643MO
  • 規(guī)格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Med12重組蛋白
  • 貨號(hào):
    CSB-EP013643MO
  • 規(guī)格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Med12重組蛋白
  • 貨號(hào):
    CSB-EP013643MO-B
  • 規(guī)格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Med12重組蛋白
  • 貨號(hào):
    CSB-BP013643MO
  • 規(guī)格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Med12重組蛋白
  • 貨號(hào):
    CSB-MP013643MO
  • 規(guī)格:
  • 來源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
  • Uniprot No.:
  • 別名:
    Med12; Kiaa0192; Mopa; Tnrc11; Trap230; Mediator of RNA polymerase II transcription subunit 12; Mediator complex subunit 12; OPA-containing protein; Thyroid hormone receptor-associated protein complex 230 kDa component; Trap230; Trinucleotide repeat-containing gene 11 protein
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. This subunit may specifically regulate transcription of targets of the Wnt signaling pathway and SHH signaling pathway.
  • 基因功能參考文獻(xiàn):
    1. Study provide evidence that Med12 regulates neural stem cell gene expression programs linked to adhesion and cell cycle progression but suppresses its adhesion by repressing the expression of cell adhesion molecules. PMID: 27188461
    2. alterations in MED12-dependent enhancer regulation may control both physiological and malignant hematopoiesis. PMID: 27570068
    3. The data reveal how the interplay between PRC1, ncRNA and Mediator complexes controls pluripotency and cellular differentiation. PMID: 27096886
    4. Med1 and Med12, two subunits of the mediator complex implicated in transcription initiation and long-range enhancer/promoter loop formation, are dynamically recruited to the IgH locus enhancers. PMID: 26903242
    5. leiomyomatous, Med12 c.131G>A variant-expressing uteri developed chromosomal rearrangements. PMID: 26193636
    6. this work points to Med12 being an essential coregulator of transcription factors controlling neural tube closure. PMID: 20589884
    7. show that in Med12 hypomorphic embryos, the Wnt/planar cell polarity pathway is disrupted and that canonical Wnt/beta-catenin signaling is impaired. PMID: 20630950
    8. Nanog and Med12 function in concert to regulate Nanog target genes and identify a novel role for Med12 in embryonic stem cell regulation. PMID: 19036726

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Nucleus.
  • 蛋白家族:
    Mediator complex subunit 12 family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 青草青草久热精品视频在线观看| 日韩午夜理论片 中文字幕| 2020精品国产自在现线官网| 欧洲av无码放荡人妇网站| 中文字幕亚洲无线码| 国产精品亚洲专区无码不卡| 99er国产这里只有精品视频免费| 伊人久久久av老熟妇色| 久久久久久一区国产精品| 男男又爽又黄又无遮挡网站| 99精品视频在线观看免费| 国产免费毛卡片| 老司机无码精品a| 精品日本一区二区免费视频| 国产丰满人妻一区二区| 久久精品国产精品国产精品污 | 丝袜无码专区人妻视频| 爆乳护士一区二区三区在线播放| 大帝a∨无码视频在线播放| 黑人玩弄人妻中文在线| 永久免费的av在线电影网无码| 无码少妇一区二区三区芒果| 久久久国产99久久国产久麻豆| 欧美亚洲另类自拍丝袜| 思思久久99热只有频精品66 | 久久久久成人精品无码中文字幕 | 天堂网www在线资源网| 18禁黄无遮挡网站| 欧美色就是色| 国产美女亚洲精品久久久| 熟妇的奶头又大又长奶水视频| 人人超人人超碰超国产97超碰| 亚洲一区二区三区香蕉| 久久精品国产自在天天线| 日本熟妇美熟bbw| 中文字幕在线日亚洲9| www国产精品内射老师| 国内精品久久久久久影院| 男人的天堂免费一区二区视频| 99国产欧美另娄久久久精品| 欧美性xxxxx极品老少|