在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Mannose-binding protein A (Mbl1)

Recombinant Mouse Mannose-binding protein A (Mbl1)

  • 中文名稱：
    小鼠Mbl1重組蛋白
  • 貨號：
    CSB-YP327925MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mbl1重組蛋白
  • 貨號：
    CSB-EP327925MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mbl1重組蛋白
  • 貨號：
    CSB-EP327925MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mbl1重組蛋白
  • 貨號：
    CSB-BP327925MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mbl1重組蛋白
  • 貨號：
    CSB-MP327925MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Mbl1
  • Uniprot No.：
  • 別名：
    Mbl1Mannose-binding protein A; MBP-A; Mannan-binding protein; Ra-reactive factor polysaccharide-binding component p28B; RaRF p28B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    18-239
  • 氨基酸序列
    SSG SQTCEDTLKT CSVIACGRDG RDGPKGEKGE PGQGLRGLQG PPGKLGPPGS VGSPGSPGPK GQKGDHGDNR AIEEKLANME AEIRILKSKL QLTNKLHAFS MGKKSGKKLF VTNHEKMPFS KVKSLCTELQ GTVAIPRNAE ENKAIQEVAT GIAFLGITDE ATEGQFMYVT GGRLTYSNWK KDEPNNHGSG EDCVIILDNG LWNDISCQAS FKAVCEFPA
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Calcium-dependent lectin. Plays a role in the innate immune response by binding mannose, fucose and N-acetylglucosamine moieties on different microorganisms and mediating activation of the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages.
  • 基因功能參考文獻(xiàn)：
    1. Our study provides comprehensive information regarding spatial and temporal expression of collectins (SP-A, SP-D and MBL-A) and their cellular sources in murine testis. Positive regulation by testosterone and alteration in their level upon LPS challenge are clues relevant to suggest their involvement in testicular immune privilege PMID: 27262512
    2. this study shows that MBL-A expression is induced in the gut in response to Candida albicans sensing and is required for intestinal homeostasis and host defense against Candida albicans PMID: 26442658
    3. Targeted deletion of Mbl1/2 causes differential levels of inflammation-related gene sets at baseline and after exposure to ozone and significantly reduces pulmonary inflammation, thus indicating an important innate immunomodulatory role of the Mbl1/2 genes. PMID: 27106289
    4. Data indicate that lysyl hydroxylase 3 is essential for the glucosyltion of mannan-binding lectin MBL-A. PMID: 25419660
    5. MBL deficiency in knockout mice reduces deposition of fibrin(ogen) in blood vessels of ischemic tissue and emphasizes a role for MBL in local thrombus formation during acute ischemia/reperfusion. PMID: 24676774
    6. Data indicate that no change of mannan-binding lectin MBL-A during the study, however, mannan-binding lectin MBL-C concentration increased in median by 3.6-fold (2.9; 4.5-fold) during the study in the diabetic group. PMID: 23350935
    7. Our data show an important role for MBL in the pathogenesis of brain ischemic injury and provide a strong support to the concept that MBL inhibition may be a relevant therapeutic target. PMID: 22879370
    8. Mannan-binding lectin has a role in diabetic kidney disease PMID: 22645604
    9. the binding of S-MBP to meprins triggers the complement activation through the lectin pathway and may cause the acute renal failure due to ischemia/reperfusion injury on kidney transplantation and hemorrhagic shock PMID: 21835783
    10. MBL deficiency plays a potentially protective role in neutrophil-mediated cerebral injury after ischemia reperfusion. PMID: 21208161
    11. Data show that genetically defined MBL-deficiency is associated with a better outcome after acute stroke. PMID: 20140243
    12. Recombinant mouse ficolin A, mannose-binding lectin-A, and mannose-binding lectin-C bound to fibrinogen in a dose-dependent manner. The lectin pathway, through mannose-binding lectins, synchronized with blood coagulation. PMID: 20375621
    13. MBL-A null mice had enhanced survival in a septic peritonitis model compared to wild-type mice PMID: 12270724
    14. MBL-A has been detected in liver, lung, kidney, and testis but not in the small intestine. PMID: 12471128
    15. MBL-A is not required for mouse survival following exposure to A. fumigatus conidia; this isoform contributes to the development and maintenance of airway hyperresponsiveness but not chronic airway remodeling during chronic fungal asthma. PMID: 14761934
    16. the MBL-dependent pathway of complement activation is a key regulator of myocardial reperfusion ischemic injury PMID: 15972690
    17. There is an MBL-dependent mechanism of host resistance against S. aureus infection. PMID: 16299314
    18. MBL has a pivotal role in the development of diabetic kidney disea PMID: 17473913
    19. Toll-like receptors 2 and 6 signaling from the phagosome is enhanced by mannose-binding lectin PMID: 18180310
    20. MBL deficiency increases susceptibility to controlled cortical impact through C3-independent mechanisms PMID: 18183030
    21. MBL-A is not a necessary component for immunity to either T. muris or S. mansoni helminths, however, MBL-A appears to be necessary for the development of specific IgM responses to nematode antigens. PMID: 19149778
    22. MBL is abundantly present and locally produced during early atherogenesis PMID: 19380618
    23. Myocardial ischemia and reperfusion injury is dependent on both IgM and mannose-binding lectin-A and -C. PMID: 19749170

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Secreted.
  • 組織特異性：
    Detected in liver and blood serum (at protein level). Detected in liver.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 亚洲精品成人av在线观看爽翻天| 国产老熟女网站| 免费观看激色视频网站| 国产美足白丝榨精在线观看sm| 免费女上男下xx00xx00视频| 日本一卡二卡3卡四卡网站精品| 亚洲高清毛片一区二区| 色多多性虎精品无码av| 国产丝袜足j在线视频播放| 天天躁日日躁狠狠躁人妻| 欧美无人区码suv| 伊人情人综合网| 国产99久久久国产精品免费看| 国产精品青青在线麻豆| 99久久99视频只有精品| 国产精品久久无码一区| 免费夜色污私人影院在线观看| 无线日本视频精品| 国产拍揄自揄精品视频| 亚洲成av人的天堂在线观看| 欧美性受xxxx黑人xyx性爽| 亚洲欧美日韩国产综合点击进入| 99久久精品国产一区二区| 久久婷婷成人综合色| 日本少妇裸体做爰高潮片| 国产极品粉嫩馒头一线天av| 久久綾合久久鬼色88| 亚洲中文无码人a∨在线| 亚洲情综合五月天| 国产精品国色综合久久| 久久五十路丰满熟女中出| 国产精品香蕉视频在线| 丁香五月欧美成人| 中文字幕av高清片| 亚洲一区在线日韩在线尤物| 萝卜视频高清免费视频日本| 玩弄人妻少妇500系列| 日日摸天天摸爽爽狠狠97| 粗大的内捧猛烈进出少妇视频| 中文字幕久热精品视频在线| 级r片内射在线视频播放|