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  4. Recombinant Mouse MCM domain-containing protein C8orf45 homolog

Recombinant Mouse MCM domain-containing protein C8orf45 homolog

  • 中文名稱：
    小鼠Mcmdc2重組蛋白
  • 貨號：
    CSB-YP518978MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mcmdc2重組蛋白
  • 貨號：
    CSB-EP518978MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mcmdc2重組蛋白
  • 貨號：
    CSB-EP518978MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mcmdc2重組蛋白
  • 貨號：
    CSB-BP518978MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mcmdc2重組蛋白
  • 貨號：
    CSB-MP518978MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Mcmdc2
  • Uniprot No.：
  • 別名：
    Mcmdc2; Minichromosome maintenance domain-containing protein 2; MCM domain-containing protein 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-681
  • 氨基酸序列
    METLQMKEAA LVYLDRSGGL QKFIDDCKSY NDSKQSYAVY RFSILIDPCD VVELDADLGN HILHHPLKAA RVFQSVCFVA VKTLSLIGQL QTETQINIVL KLTHLPALPS YTLDLCEFPL NYASQRFYMM QGIVIAMTTI TKYTQGARFL CSDGVCPLSK GFQYVRVHVP GATESATVRN DFLCSLCSSS LQEDRKFRVL GDKQIVEIIT TKMFHAFQGD SKNQPFRFQS LGIFLRDELV NKMKIGNEYK IIGIPVCVKT SQTALCVEAN NITPHTAKVP LGISDNFRRL LSLTSSSCWK FTAMLANVFA SQIVAPGTYN LLKLCLLMSL VQTRDCNRER EDCLDILVIT SDTLLVDRLL NFSMNLVSRG IRHPVCTEVF PTVSRNKYGT GAVSIQAGSA LLAKGGICFI GDLTSHKKDK LEQLQSALES RSVTVFIPGK KFGDDFDQQM TFPIQCSFWS FVDMDSSSRR NVQKTSTLIG QMDCSLIPAN LAEAFGLLIN CSEASPCHPL LPTVQHTLKK AVEPEGLLYL ASKQFTTEDF EKLLAFAKSL NMEFSLEAER MIHGYYLASR RIRTDSIHGS KLSASALKYL VSLSEAHARL SLRTTVLRED ALIAALLLEI SLTLRYGATP FCVAPNALFP FELYNEEYLE QRDLYLTQCQ QQLQQFIATC GPGTTVFSSD E
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Plays an important role in meiotic recombination and associated DNA double-strand break repair.
  • 基因功能參考文獻：
    1. In MCMDC2-deficient mice meiosis is arrested in prophase I, and is characterized by persistent meiotic double-stranded DNA breaksfailure of homologous chromosome synapsis and XY body formation, and an absence of crossing over. PMID: 27986806
    2. our work suggests that MCMDC2 plays an important role in either the formation, or the stabilization, of DNA strand invasion events that promote homologue alignment and provide the basis for inter-homologue crossover formation during meiotic recombination. PMID: 27760146
  • 組織特異性：
    Predominantly expressed in the gonads and the brain. Not detected in the heart, lung, nor embryonic fibroblasts.
  • 數據庫鏈接：


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