在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Lysyl oxidase homolog 1 (Loxl1)

  • 中文名稱:
    小鼠Loxl1重組蛋白
  • 貨號(hào):
    CSB-YP013040MO
  • 規(guī)格:
    ¥2208
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產(chǎn)品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    Loxl1
  • Uniprot No.:
  • 別名:
    Loxl1; Lox2; Loxl; Lysyl oxidase homolog 1; EC 1.4.3.-; Lysyl oxidase 2; Lysyl oxidase-like protein 1
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Yeast
  • 分子量:
    58.5kDa
  • 表達(dá)區(qū)域:
    95-607aa
  • 氨基酸序列
    RQAPSLPLPGRVGSDTVRGQTRHPFGFGQVPDNWREVAVGDSTGMARARTSVSQQRHGGSASSSVSASAFATTYRQPSPYPQQFPYPQAPFVNQYENYDPASRTYEQGYVYYRGAGGGMGAGAAAVASAGVIYPFQPRARYEDYGGGGGEEQPEYPAQGFYPAPERPYVPQPQPQPQPQPQPQPQPSDGLDRRYSHSLYNEGTPGFEQAYPDPSTDVSQAPAGAGGTYGGAGDPRLGWYPPYAANVPPEAYVPPRAVEPQPPFRVLEPPYLPVRSSDAPSQGGERNGAQQGRLSVGSVYRPNQNGRGLPDLVPDPNYVQASTYVQRAHLYSLRCAAEEKCLASTAYAPEATDYDLRVLLRFPQRVKNQGTADFLPNRPRHTWEWHSCHQHYHSMDEFSHYDLLDASTGKKVAEGHKASFCLEDSTCDFGNLKRYACTSHTQGLSPGCYDTYNADIDCQWIDITDVQPGNYILKVHVNPKYIVLESDFTNNVVRCNIHYTGRYVSTTNCKIVQS
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標(biāo)簽:
    N-terminal 6xHis-tagged
  • 產(chǎn)品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Active on elastin and collagen substrates.
  • 基因功能參考文獻(xiàn):
    1. findings strongly suggested that elastin crosslinking and LOXL1 were co-associated with liver cirrhosis, while selective inhibition of LOXL1 arrested disease progression by reducing crosslinking of elastin. PMID: 29366776
    2. LOXL1-/- mutant mice develop appendicular and axial skeletal phenotypes characterized by decreased bone volume fraction and compromised trabecular microstructure, predominantly in females PMID: 26538021
    3. Elimination of LOXL1 in mice impairs the blood-aqueous humor barrier in the ocular anterior segment and causes lens abnormalities consistent with cataract formation, but does not result in deposition of macromolecular material or glaucoma. PMID: 24425853
    4. There is a possible fundamental role of LOXL-1 in cardiac hypertrophy. PMID: 22763477
    5. loxl appears non-allelic to rough coat in mice; heart- and skin-specific downregulation of LOXL in rough coat mice, however, may contribute to the extracellular matrix alterations and the rough coat phenotype PMID: 15482472
    6. Data report that cells in the hippocampal granule cell layer of LOXL -/- mice have significantly smaller somas and muted long-term potentiation compared to LOXL +/+ mice. PMID: 16157454
    7. LOXL1 deficiency caused failure of elastic fiber homeostasis leading to pelvic floor disorders PMID: 16436666
    8. LOXL1 (lysyl oxidase-like 1) mutation results in a global defect in connective tissues and correlates with altered biomechanical behavior of the vagina and supportive tissues PMID: 18265927
    9. LOXL1-KO lower urogenital tract anatomical and functional phenotype resembles female pelvic floor dysfunction in humans. Elastin disorganization may lead to such functional abnormalities. PMID: 18495804
    10. Loxl1(-/-) males bred with control females demonstrated relative fecundity values intermediate between Loxl1(-/-) pairs (lowest fecundity) and control pairs (highest fecundity), suggesting a component of male-factor infertility. PMID: 19201700

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Secreted, extracellular space.
  • 蛋白家族:
    Lysyl oxidase family
  • 數(shù)據(jù)庫鏈接:


主站蜘蛛池模板: 99精品免视看| 国产精品sm捆绑调教视频| 激情综合五月丁香亚洲| 国产一起色一起爱| 亚洲精品无码不卡在线播he| 99久久久无码国产精品秋霞网| 精品国产国语对白久久免费| 中文无码日韩欧av影视| 性欧美vr高清极品| 欧美gv在线观看| 乱中年女人伦av二区| 国产精品亚洲第一区在线观看 | 国产精品亚洲成在人线| 无码免费无线观看在线视| 亚洲乱色熟女一区二区三区丝袜| 久久精品人妻无码一区二区三区 | 欧美熟妇乱子伦xx视频| 国产末成年女av片一区二区| 亚洲欧美另类久久久精品| 欧美变态另类xxxx| 67194熟妇人妻欧美日韩| 亚洲国产精品va在线看黑人| 久无码久无码av无码| 国产模特嫩模私拍视频在线| 亚洲熟妇丰满xxxxx| 中文无码乱人伦中文视频在线v| 99精品国产再热久久无毒不卡 | 色妞www精品视频| 99国产欧美久久久精品蜜芽| 久久亚洲精品国产精品婷婷| 中文字幕av无码一二三区电影 | 国农村精品国产自线拍| 国产精品久久久久久无毒不卡| 天天看片视频免费观看| 国产成人无码视频网站在线观看| 亚洲国产精品久久久久久无码| 精品无码国产自产拍在线观看蜜 | 色777狠狠狠综合| 自拍偷自拍亚洲精品情侣| 亚洲色成人一区二区三区小说| 日日摸天天摸人人看|