在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Lysosome membrane protein 2 (Scarb2), partial

Recombinant Mouse Lysosome membrane protein 2 (Scarb2), partial

  • 中文名稱：
    小鼠Scarb2重組蛋白
  • 貨號：
    CSB-YP020768MO1
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Scarb2重組蛋白
  • 貨號：
    CSB-EP020768MO1
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Scarb2重組蛋白
  • 貨號：
    CSB-EP020768MO1-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Scarb2重組蛋白
  • 貨號：
    CSB-BP020768MO1
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Scarb2重組蛋白
  • 貨號：
    CSB-MP020768MO1
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Scarb2; Lysosome membrane protein 2; 85 kDa lysosomal membrane sialoglycoprotein; LGP85; Lysosome membrane protein II; LIMP II; Scavenger receptor class B member 2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting.
  • 基因功能參考文獻：
    1. LIMP-2 facilitates transport of phospholipids into murine fibroblasts, with a strong substrate preference for phosphatidylserine. PMID: 29199275
    2. The findings identify SR-BII as a functional SAA receptor that mediates SAA uptake and contributes to its proinflammatory signaling via the MAPK-mediated signaling pathways. PMID: 28423002
    3. AP-3-dependent LB targeting is facilitated by protein/protein interaction between LIMP-2/SCARB2 and PRDX6 in vitro and in vivo PMID: 26907692
    4. Heterologous expression of the luminal domain of LIMP-2 in wild-type cells. PMID: 26219725
    5. In LIMP-2-deficient brains a significant reduction in GC activity led to lipid storage, disturbed autophagic/lysosomal function, and alpha-synuclein accumulation. PMID: 25316793
    6. absence of Limp-2 reduces inflammation in experimental crescentic glomerulonephritis with decreased macrophage and T-cell infiltration in the kidney. PMID: 24394995
    7. Limp-2 deficiency leads to a minor increase in circulating renin. Limp-2, however, is not required for acute or chronic stimulation of renin release. PMID: 23635510
    8. The SR-BII is involved in cholesterol ester uptake for steroidogenesis and spermatogenesis in the testis. PMID: 22988039
    9. The residues between 144 and 151 are critical for SCARB2 binding to VP1 of EV71 and seven residues from the human receptor could convert murine SCARB2, an otherwise inefficient receptor, to an efficient receptor for EV71 viral infection. PMID: 22219187
    10. The data suggest that tubular proteinuria in Limp-2(-/-) mice is due to failure of endosomes containing reabsorbed proteins to fuse with lysosomes in the proximal tubule of the kidney. Failure of proteolysis is a novel mechanism for tubular proteinuria. PMID: 21429972
    11. The coiled-coil structure of LIMP-2 is required for its interaction with beta-glucocerebrosidase. PMID: 19933215
    12. CD36 is not essential for MHC class I cross-presentation of cell-associated antigen by CD8 alpha+ dendritic cells. PMID: 12055214
    13. CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo. PMID: 12055215
    14. Overexpression of LGP85 causes an enlargement of early endosomes and late endosomes/lysosomes. LGP85 may participate in reorganizing the endosomal/lysosomal compartments. PMID: 12356916
    15. SR-A and CD36 are responsible for the preponderance of modified LDL uptake in macrophages and that other scavenger receptors do not compensate for their absence PMID: 12376530
    16. LIMP-2/LGP85 deficiency causes ureteric pelvic junction obstruction, deafness and peripheral neuropathy in mice PMID: 12620969
    17. Our findings suggest an important role for LIMP2 in the control of the localization and the level of apically expressed membrane proteins such as KCNQ1, KCNE1 and megalin in the stria vascularis. PMID: 16901941
    18. Peritoneal macrophages isolated from SR-BI/BII-knockout mice demonstrated a 30% decrease in bacterial uptake when compared with macrophages from normal mice. PMID: 17071747
    19. Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy. PMID: 17485520
    20. These data support a role for LIMP-2 as the mannose-6-phosphate-independent trafficking receptor for beta-glucocerebrosidase. PMID: 18022370

    顯示更多

    收起更多

  • 亞細胞定位：
    Lysosome membrane; Multi-pass membrane protein.
  • 蛋白家族：
    CD36 family
  • 組織特異性：
    Detected in the extracts of brain, heart, lung, liver and kidney.
  • 數據庫鏈接：


主站蜘蛛池模板： 欧洲日韩亚洲无线在码| 精品黑人一区二区三区久久| 少妇被粗大的猛进69视频| 久久精品国产亚洲欧美成人| 无遮挡激情视频国产在线观看| 欧洲人免费视频网站在线| 国产精品午夜视频自在拍| 漂亮人妻被中出中文字幕| 国产在线观看码高清视频| 亚洲欧美日韩中文加勒比| 亚洲男人的天堂成人www| 亚洲精品中文字幕无码蜜桃| 国产乱视频在线观看| 免费无码一区二区三区蜜桃大| 97人妻免费公开在线视频| 日韩视频 中文字幕 视频一区| 无码日韩精品一区二区人妻| 日韩精品无码一区二区| 国产精品人成在线播放新网站| 夜夜天天噜狠狠爱2019| 中文字幕乱码亚洲无线三区 | 国内精品久久久久精免费| 2021精品亚洲中文字幕| 人禽伦免费交视频播放| 国产又爽又猛又粗的视频a片| 国产xxxx69真实实拍| 美女裸免费观看网站| 高清不卡一区二区三区| 久久欧美国产伦子伦精品| 成在人线av无码免费高潮喷水 | 中文人妻熟妇乱又伦精品| 国产产品亚洲产品| www亚洲精品少妇裸乳一区二区| 欧美色就是色| 双乳奶水饱满少妇呻吟免费看| 亚洲精品无码久久久| 亚洲va欧美va天堂v国产综合| 亚洲精品无码久久毛片| 国产亚洲综合久久系列| 亚洲日韩成人av无码网站| 青草内射中出高潮|