在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Lysine-specific demethylase NO66 (No66)

Recombinant Mouse Lysine-specific demethylase NO66 (No66)

  • 中文名稱：
    小鼠Riox1重組蛋白
  • 貨號：
    CSB-YP872853MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Riox1重組蛋白
  • 貨號：
    CSB-EP872853MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Riox1重組蛋白
  • 貨號：
    CSB-EP872853MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Riox1重組蛋白
  • 貨號：
    CSB-BP872853MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Riox1重組蛋白
  • 貨號：
    CSB-MP872853MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Riox1
  • Uniprot No.：
  • 別名：
    Riox1; Mapjd; No66; MNCb-7109; Ribosomal oxygenase 1; Bifunctional lysine-specific demethylase and histidyl-hydroxylase NO66; EC 1.14.11.-; EC 1.14.11.27; Histone lysine demethylase NO66
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-603
  • 氨基酸序列
    MDELPNGNGA ALLKRGRGRR RRHPQSQPRG ASVLALPLRP RKIRRHRKSA AASRVAALRA RALRSEDSDS KVAVASVRGK RKRPAELLEA SRSAEPRPVS ARPRSASATL PSRVEGWAAL SRNLGTAAPP PPGSHADEPG RPRASPLQQV LTELNGIPSS RRRAARLFEW LLAPLPPDHF YRRLWEREAV LVRRQDRSYY EGLFSTADLD SMLRYEDVQF GQHLDAARYV DGRRETLNPP GRALPAAAWS LYRAGCSLRL LCPQAFSPTV WQFLAVLQEQ FGSMAGSNVY LTPPDSQGFA PHYDDIEAFV LQLEGRKLWR VYRPRDPSEE LALTSSPNFS QEDLGEPVLQ TVLEPGDLLY FPRGFIHQAE CQDGVHSLHL TLSTYQRNTW GDFLEAVLPL AVQAAIEENV EFRRGLPRDF MDYMGAQHSD SKDPRRTAFM EKVRVLVARL GHFAPVDAVA DQRAKDFIHD SLPPVLTDRE RALSVHGLPV RWEAGEPVNV GAQLTTETQV HMLQDGVARL VGEGGRLFLY HTVENSRVYH LEEPKCLEIH PQQADAMELL LRSYPEFVRV GDLPCDSVED QLSLATMLYD KGLLLTKTPL VPS
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Oxygenase that can act as both a histone lysine demethylase and a ribosomal histidine hydroxylase Also catalyzes the hydroxylation of 60S ribosomal protein L8 on 'His-216'. Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation. May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region. Participates in MYC-induced transcriptional activation. Specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2).
  • 基因功能參考文獻：
    1. NO66 regulates bone formation, at least in part, via regulating the number of bone-forming cells and expression of multiple genes that are critical for these processes PMID: 25736226
    2. Data indicate that mesenchymal overexpression of nucleolar protein 66 (NO66) inhibits skeletal cell proliferation. PMID: 25746793
    3. propose that Osx is a molecular switch for the formation of an active chromatin state during osteoblast differentiation, whereas NO66 helps gene repression through histone demethylation and/or formation of a repressor complex PMID: 24115157
  • 亞細胞定位：
    Nucleus, nucleolus. Nucleus, nucleoplasm.
  • 蛋白家族：
    ROX family, NO66 subfamily
  • 組織特異性：
    Present in developing bones (at protein level). Widely but not ubiquitously expressed.
  • 數據庫鏈接：


主站蜘蛛池模板： 精品一卡二卡三卡| 污18禁污色黄网站免费| 天堂网www在线资源中文| 欧美日韩不卡高清在线看| 国产孩cao大人xxxx| 日本大肚子孕妇交xxx| 亚洲人成电影网站在线观看| 精品国内在视频线2019| 中日av乱码一区二区三区乱码| 精国产品一区二区三区a片| 久久www免费人成_看片| 国产日产欧产精品精品app| 国产农村乱子伦精品视频| 玩两个丰满老熟女久久网| 亚洲精品一线二线三线无人区| 成人片黄网站a毛片免费| 狠狠躁日日躁夜夜躁2020| av无码天堂一区二区三区| 欧美日韩国产中文高清视频| 双乳奶水饱满少妇呻吟| 国产精品爽爽久久久久久| 国产精品久久久久久| 一本一道vs无码中文字幕| 亚洲精品无码精品mv在线观看| 国产精品白丝av网站在线观看| 无码专区人妻系列日韩精品少妇| 国产精品久久自在自线青柠| 无码人妻巨屁股系列| 中文字幕人妻丝袜乱一区三区| 一本大道无码日韩精品影视丶| 中文字幕精品一区二区精品| 动漫av一区二区在线观看| 国产 日韩 另类 视频一区| 奶头又大又白喷奶水av| 精品久久久久久无码中文野结衣| 99久久精品美女高潮喷水| 尹人香蕉久久99天天拍欧美p7| 天堂www天堂在线资源| 成人爽a毛片免费| 久久久精品人妻久久影视| 亚洲理论在线a中文字幕|