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  4. Recombinant Mouse Lupus La protein homolog (Ssb)

Recombinant Mouse Lupus La protein homolog (Ssb)

  • 中文名稱：
    小鼠Ssb重組蛋白
  • 貨號：
    CSB-YP022705MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Ssb重組蛋白
  • 貨號：
    CSB-EP022705MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Ssb重組蛋白
  • 貨號：
    CSB-EP022705MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Ssb重組蛋白
  • 貨號：
    CSB-BP022705MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Ssb重組蛋白
  • 貨號：
    CSB-MP022705MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Ssb; Ss-b; Lupus La protein homolog; La autoantigen homolog; La ribonucleoprotein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-415
  • 氨基酸序列
    MAENGDNEKM TALEAKICHQ IEYYFGDFNL PRDKFLKEQI KLDEGWVPLE TMIKFNRLNR LTTDFNVIVQ ALSKSKAKLM EVSADKTKIR RSPSRPLPEV TDEYKNDVKN RSVYIKGFPT DATLDDIKEW LDDKGQILNI QMRRTLHKTF KGSIFAVFDS IQSAKKFVEI PGQKYKDTNL LILFKEDYFA KKNEERKQSK VEAKLKAKQE HEGRHKPGST ETRALEGKMG CLLKFSGDLD DQTCREDLHF LFSNHGEIKW VDFARGAKEG IILFKEKAKE ALEKARNANN GNLLLRNKKV TWKVLEGHAE KEALKKITDD QQESLNKWKS KGGHAGGRFK GSHVFTAARR FKGKGKGNRP GYAGAPKGRG QFHGRRTRFD DDDRRRGPMK RGRDGRDREE PASKHKKREN GARDK
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to the 3' poly(U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation.
  • 基因功能參考文獻：
    1. La deletion is associated with Neuron Death and Reactive Astrocytosis. PMID: 28223366
    2. Data indicate that La antigen (Sjogren's syndrome antigen B) is essential in different cell types and required for normal development of various tissue types. PMID: 24190965
    3. Overexpression of mouse or human La enhanced M-MuLV particle release in the absence of glycosylated gag. PMID: 21343359
    4. Blastocysts derived from La+/- intercrosses yielded 38 La+/+ and La+/- embryonic stem (ES) cell lines but no La-/- ES cell lines, suggesting that La contributes a critical function toward the establishment or survival of ES cells. PMID: 16449655
    5. Overexpression of La autoantigen is associated with lymphoma PMID: 17875784
    6. truncation of La alters the immunodominance hierarchy of T cell responsiveness to hLa and may be a factor in the initiation or maintenance of anti-La autoimmunity. PMID: 17907193
    7. La appears to be an important contributor to Akt-mediated translational regulation of these transcripts in murine glial cells. PMID: 18836485

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  • 亞細胞定位：
    Nucleus.
  • 數據庫鏈接：


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