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  4. Recombinant Mouse Limbic system-associated membrane protein (Lsamp), partial

Recombinant Mouse Limbic system-associated membrane protein (Lsamp), partial

  • 中文名稱：
    小鼠Lsamp重組蛋白
  • 貨號：
    CSB-YP013197MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Lsamp重組蛋白
  • 貨號：
    CSB-EP013197MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Lsamp重組蛋白
  • 貨號：
    CSB-EP013197MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Lsamp重組蛋白
  • 貨號：
    CSB-BP013197MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Lsamp重組蛋白
  • 貨號：
    CSB-MP013197MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Lsamp
  • Uniprot No.：
  • 別名：
    Lsamp; Limbic system-associated membrane protein; LSAMP
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 表達區域：
    -
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Mediates selective neuronal growth and axon targeting. Contributes to the guidance of developing axons and remodeling of mature circuits in the limbic system. Essential for normal growth of the hyppocampal mossy fiber projection.
  • 基因功能參考文獻：
    1. Limbic system-associated membrane protein is involved in emotional and social operating systems by complex regulation of two alternative promoters. PMID: 24633737
    2. Lsamp(-/-) mice are a promising model to study the neurobiological mechanisms of deviant social behaviour and adaptation impairment observed in many psychiatric disorders. PMID: 23206697
    3. Lsamp-deficient mice were less sensitive to isolation stress than their wild-type littermates. PMID: 22155487
    4. results suggest that LAMP protein is not crucial for the general development of anatomical brain structures, but is needed for specific neural circuits that regulate anxiety-related and social behaviour. PMID: 20888367
    5. lsamp knockout mice have a deficit in spatial memory acquisition and poorly sustained CA1 long-term potentiation. PMID: 20385375
    6. genomic features of the Lsamp gene indicate an intricate mechanism of gene expression regulation that may be relevant in the context of human neuropsychiatric and neurological disorders, where LAMP expression may be altered PMID: 15081109
    7. Genetic deletion of Lsamp causes exaggerated behavioral activation in novel environments. PMID: 18199495

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  • 亞細胞定位：
    Cell membrane; Lipid-anchor, GPI-anchor.
  • 蛋白家族：
    Immunoglobulin superfamily, IgLON family
  • 數據庫鏈接：

    UniGene: Mm.310524



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