在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Latexin (Lxn)

Recombinant Mouse Latexin (Lxn)

  • 中文名稱：
    小鼠Lxn重組蛋白
  • 貨號(hào)：
    CSB-YP013240MO
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Lxn重組蛋白
  • 貨號(hào)：
    CSB-EP013240MO
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Lxn重組蛋白
  • 貨號(hào)：
    CSB-EP013240MO-B
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Lxn重組蛋白
  • 貨號(hào)：
    CSB-BP013240MO
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Lxn重組蛋白
  • 貨號(hào)：
    CSB-MP013240MO
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Lxn
  • Uniprot No.：
  • 別名：
    LxnLatexin; Endogenous carboxypeptidase inhibitor; ECI; Tissue carboxypeptidase inhibitor; TCI
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Full length protein
  • 表達(dá)區(qū)域：
    1-222
  • 氨基酸序列
    MEIPPTHYAA SRAASVAENC INYQQGTPHK LFLVQTVQQA SKEDIPGRGH KYHLKFSVEE IIQKQVTVNC TAEVLYPQMG QGSAPEVNFT FEGEIGKNPD EEDNTFYQSL MSLKRPLEAQ DIPDNFGNVS PQMKPVQHLA WVACGYVMWQ NSTEDTWYKM LKIQTVKQVQ RNDDFIELDY TILLHDIASQ EIIPWQMQVL WHPQYGTKVK HNSRLPKEGQ AE
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Hardly reversible, non-competitive, and potent inhibitor of CPA1, CPA2 and CPA4. May play a role in inflammation.
  • 基因功能參考文獻(xiàn)：
    1. By using an Lxn knockout mouse model, this study found that Lxn inactivation in vivo led to the physiological expansion of the entire hematopoietic hierarchy. Loss of Lxn enhanced the competitive repopulation capacity and survival of hematopoietic stem cells in a cell-intrinsic manner. PMID: 28330618
    2. Rps3 knockdown increased the radiation sensitivity of FDC-P1, confirming that the mechanism of action of Lxn is mediated by Rps3 pathway. PMID: 25341047
    3. These results are consistent with a tumor suppressor role for latexin. PMID: 23028717
    4. Latexin is preferentially expressed in hematopoietic stem cells, and is co-localized with the molecules responsible for the interaction of hematopoietic stem cells with a bone marrow niche. PMID: 21567403
    5. Data indicate that AAV-mediated latexin transduction or administration of a small molecule carboxypeptidase A inhibitor significantly reduced acetone-evoked nociceptive behavior after SNI. PMID: 21572518
    6. The crystal structure of mouse latexin, solved at 1.83 A resolution, shows no structural relationship with other carboxypeptidase inhibitors. PMID: 15698574
    7. Latexin is involved in the transmission of pain, since mice lacking this protein experience reducted pain sensitivity. PMID: 16469302
    8. promoter polymorphisms between the B6 and D2 alleles may affect Lxn gene expression and consequently influence the population size of hematopoietic stem cells. PMID: 17220891
    9. These results indicate that latexin is involved in BMP-2-induced chondrocyte differentiation and plays an important role in skeletogenesis and skeletal regeneration. PMID: 19059214

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm.
  • 蛋白家族：
    Protease inhibitor I47 (latexin) family
  • 組織特異性：
    Highly enriched in macrophages.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 西西人体午夜大胆无码视频| 欧美506070老妇乱子伦| 欧美人与动牲交zooz男人| 日韩在线一区二区不卡视频| 内射一区二区精品视频在线观看 | 亚洲 欧美 天堂 综合| 国产欧美日韩精品专区| 无码国产精品久久一区免费| 人人澡超碰碰97碰碰碰| 伊人久久大香线蕉av最新| 亚洲精品无码久久久久av麻豆| 蜜臀av色欲a片无码一区二区| 亚洲精品欧美二区三区中文字幕| 人妻精油按摩bd高清中文字幕| 免费视频爱爱太爽了激情| 免费人成又黄又爽的视频| 丰满少妇被猛烈进av毛片| 国产精品va无码一区二区| 性夜夜春夜夜爽aa片a| 2020年最新国产精品正在播放| 国产拍揄自揄精品视频| 小鲜肉自慰网站| 久久精品这里热有精品| 无码人妻精品中文字幕不卡| 婷婷综合缴情亚洲| 一边吃奶一边摸做爽视频| 国产精品无码成人午夜电影| 天堂а√中文最新版在线| 亚洲国产制服丝袜高清在线| 中文精品久久久久人妻不卡| 肉大榛一进一出免费视频| 韩国久久久久久级做爰片| 精品国产高清毛片a片看| 色婷婷综合中文久久一本| 午夜性开放午夜性爽爽| 国产精品丝袜亚洲熟女| 欧美xxxx黑人又粗又长| 国产精品精华液网站| 国产欧美日韩综合视频专区| 国产精品a久久777777| 少妇人妻偷人激情视频|