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  4. Recombinant Mouse Killer cell lectin-like receptor 5 (Klra5), partial

Recombinant Mouse Killer cell lectin-like receptor 5 (Klra5), partial

  • 中文名稱：
    小鼠Klra5重組蛋白
  • 貨號(hào)：
    CSB-YP730644MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Klra5重組蛋白
  • 貨號(hào)：
    CSB-EP730644MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Klra5重組蛋白
  • 貨號(hào)：
    CSB-EP730644MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Klra5重組蛋白
  • 貨號(hào)：
    CSB-BP730644MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Klra5重組蛋白
  • 貨號(hào)：
    CSB-MP730644MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Klra5
  • Uniprot No.：
  • 別名：
    Klra5; Ly-49e; Ly49-e; Ly49e; Killer cell lectin-like receptor 5; Lymphocyte antigen 49e; Ly-49e; T-cell surface glycoprotein Ly-49E
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    Partial
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Receptor on natural killer (NK) cells for class I MHC.
  • 基因功能參考文獻(xiàn)：
    1. Ly49E is highly expressed on epidermal gammadelta T cells and liver NK cells, this receptor does not play a major role in the control of skin tumour formation or in lung and liver tumour development. PMID: 27469529
    2. this study shows that Ly49E expression on intraepithelial lymphocytes does not influence the development or progression of intestinal cancer PMID: 27585789
    3. Ly49E is expressed on a high proportion of CD8alphaalpha-positive intestinal intraepithelial lymphocytes. PMID: 25310588
    4. Ly49E expression is not crucial for liver NK cell differentiation during ontogeny PMID: 23475576
    5. Two Ly49e expression pathways have been identified in the intraepithelial resting and activated gammadelta T cells. PMID: 23338239
    6. Ly49E is expressed in a probabilistic manner in adult natural killer (NK)cells and T cells. PMID: 21248256
    7. NK cells developing in vitro from fetal progenitors in the presence of IL-2 fact express high levels of at least one previously uncharacterized member of the Ly49 family, most likely Ly49E. PMID: 11870631
    8. Inhibitory receptor Ly49E is expressed on mature fetal thymic and adult epidermal TCR Vgamma3+ lymphocytes. PMID: 11907085
    9. addition of uPA to Ly49E-positive adult and fetal NK cells inhibits interferon-gamma secretion and reduces their cytotoxic potential, respectively PMID: 18784372

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  • 亞細(xì)胞定位：
    Membrane; Single-pass type II membrane protein.
  • 組織特異性：
    Mostly expressed in NK cells, but also observed on NK T and memory T-cells.
  • 數(shù)據(jù)庫鏈接：


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