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  4. Recombinant Mouse Keratin, type II cytoskeletal 6A (Krt6a)

Recombinant Mouse Keratin, type II cytoskeletal 6A (Krt6a)

  • 中文名稱：
    小鼠Krt6a重組蛋白
  • 貨號：
    CSB-YP012561MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Krt6a重組蛋白
  • 貨號：
    CSB-EP012561MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Krt6a重組蛋白
  • 貨號：
    CSB-EP012561MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Krt6a重組蛋白
  • 貨號：
    CSB-BP012561MO
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Krt6a重組蛋白
  • 貨號：
    CSB-MP012561MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Krt6a
  • Uniprot No.：
  • 別名：
    Krt6a; Ker2; Krt2-6; Krt2-6a; Krt6; Keratin; type II cytoskeletal 6A; Cytokeratin-6A; CK-6A; Keratin-6-alpha; mK6-alpha; Keratin-6A; K6A
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區(qū)域：
    1-553
  • 氨基酸序列
    MSTKTTIKSQ TSHRGYSASS ARVPGLNRSG FSSVSVCRSR GSGGSSAMCG GAGFGSRSLY GVGSSKRISI GGGSCGIGGG YGSRFGGSFG IGGGAGSGFG FGGGAGFGGG YGGAGFPVCP PGGIQEVTIN QSLLTPLNLQ IDPTIQRVRT EEREQIKTLN NKFASFIDKV RFLEQQNKVL DTKWALLQEQ GTKTVRQNLE PMFEQYISNL RRQLDSIIGE RGRLDSELRN MQDTVEDYKS KYEDEINKRT AAENEFVTLK KDVDAAYMNK VELQAKADSL TDDINFLRAL YEAELSQMQT HISDTSVVLS MDNNRSLDLD SIIAEVKAQY EDIAQRSRAE AESWYQTKYE ELQVTAGRHG DDLRNTKQEI AEINRMIQRL RSEIDHVKKQ CANLQAAIAD AEQRGEMALK DARGKLEGLE DALQKAKQDM ARLLKEYQEL MNVKLALDVE IATYRKLLEG EECRLNGEGV GPVNISVVQS TVSSGYGSAG GASSSLGLGG GSSYSYSSSH GLGGGFSAGS GRAIGGGLSS SGGLSSSTIK YTTTSSSKKS YRQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Epidermis-specific type I keratin involved in wound healing. Involved in the activation of follicular keratinocytes after wounding, while it does not play a major role in keratinocyte proliferation or migration. Participates in the regulation of epithelial migration by inhibiting the activity of SRC during wound repair.
  • 基因功能參考文獻：
    1. Although K6a was not essential for mammary gland development, loss of both K6a and K6b resulted in an increase in PR-positive mammary epithelial cells and decreased proliferation after exposure to steroid hormones PMID: 16790075
    2. mK6a and mK75 thus exhibit temporally distinct, and spatially opposed, expression patterns in the companion layer (Cl) during postnatal anagen. PMID: 17170733
  • 蛋白家族：
    Intermediate filament family
  • 組織特異性：
    Predominates in the adult trunk skin, tongue, trachea/esophagus and eye. In adult skin, localization is restricted to hair follicles, where it is localized predominantly in the outer root sheath.
  • 數(shù)據(jù)庫鏈接：


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