在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Interleukin-1 receptor-associated kinase 1-binding protein 1 (Irak1bp1)

Recombinant Mouse Interleukin-1 receptor-associated kinase 1-binding protein 1 (Irak1bp1)

  • 中文名稱：
    小鼠Irak1bp1重組蛋白
  • 貨號(hào)：
    CSB-YP863673MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Irak1bp1重組蛋白
  • 貨號(hào)：
    CSB-EP863673MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Irak1bp1重組蛋白
  • 貨號(hào)：
    CSB-EP863673MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Irak1bp1重組蛋白
  • 貨號(hào)：
    CSB-BP863673MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Irak1bp1重組蛋白
  • 貨號(hào)：
    CSB-MP863673MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Irak1bp1
  • Uniprot No.：
  • 別名：
    Irak1bp1; Aip70; Simpl; Interleukin-1 receptor-associated kinase 1-binding protein 1; IRAK1-binding protein 1; ActA-binding protein 70; PLK-interacting protein; Signaling molecule that associates with the mouse pelle-like kinase; SIMPL
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-259
  • 氨基酸序列
    MSLQPAPASR VFMELVPWAD RGRENHPISA AEAQPIGRRP HVAEAHPGAR EVHVSGAAEV SASPDRALVT VRVSSTKEVS AEAKKSVCRR LDYITQSLQQ QGFQAENVTV TKNIRRVENA YHMEAEVCIT FTEFGKMQNI CNFLVEKLDS SVVISPPEFY HTPGSVENLR RQACLVAVEN AWRKAQEVCD LVGQTLGKPL LIKEEETKDW EGQTDDHQLS RLPGTLTVQQ KIKSATIHAA SKVFITFEVK GKEKKKKHL
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the IRAK1-dependent TNFRSF1A signaling pathway that leads to NF-kappa-B activation and is required for cell survival. Acts by enhancing RELA transcriptional activity.
  • 基因功能參考文獻(xiàn)：
    1. SIMPL functions as a TNFalpha-dependent p65 co-activator by facilitating the recruitment of MED1 to p65 containing transcriptional complexes to control the expression of a subset of TNFalpha-induced genes. PMID: 23630580
    2. IRAK1BP1 functions through its effects on NF-kappaB as a molecular switch to bias innate immune pathways toward the resolution of inflammation PMID: 20534545
    3. Signals transduced through the tumor necrosis factor-alpha-tumor necrosis factor -receptor I-SIMPL(substrate that interacts with mouse pelle-like kinase) pathway support hematopoietic progenitor cell survival, growth and differentiation PMID: 19941935
    4. TNF-alpha activation of NF-kappaB dependent-gene expression requires nuclear relocalization of p65 as well as nuclear relocalization of SIMPL, generating a TNF-alpha-specific induction of gene expression. PMID: 15485901
    5. Hsp70/Hsc70 bind the intrinsically disordered amino-terminal region of SIMPL to stabilize the protein and thereby regulate its activity. PMID: 17233114
    6. IRAK1BP1 regulates transcription of a specific subset of Toll-like receptor responsive genes, producing an overall antiinflammatory profile PMID: 18268037

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    IRAK1BP1 family
  • 組織特異性：
    Expressed in testis, brain, kidney, liver and heart.
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 欧美人和黑人牲交网站上线| 国产精品99久久免费观看| 麻豆精品久久久久久中文字幕无码 | 国产欠欠欠18一区二区| 亚洲欧美日本久久综合网站点击| 伊人久久大香线蕉综合5g| 奇米影视7777久久精品人人爽| 久9视频这里只有精品| 乱人伦中文视频在线| 久久亚洲中文无码咪咪爱| 午夜dj在线观看高清在线视频完整版| 性色av一区二区三区无码| 色悠久久久久综合网香蕉| 丰满人妻无奈张开双腿av| 亚洲国产精品一区二区成人片国内| 久久一日本道色综合久久| 三上悠亚的av片在线无码| 久久99精品久久久久久久不卡 | 久久久久99精品成人片三人毛片| 天堂一区人妻无码| 亚洲综合色区另类小说| 国产精品久久久久无码av1| 无码粉嫩虎白一线天在线观看| 女人高潮被爽到呻吟在线观看| 女人被黑人躁得好爽视频| 不卡无码人妻一区二区三区| 大地资源中文在线观看官网第二页| 国产精品久久久久av福利动漫| 久久不见久久见免费视频6无删减| 真实国产乱子伦对白在线播放| 欧美亚洲综合在线一区| 9九色桋品熟女内射| 精品国产v无码大片在线观看| 久久精品无码专区免费| 精品人体无码一区二区三区| 成人av久久一区二区三区| 九九综合va免费看| 99在线精品免费视频| 亚洲制服 视频在线观看| 久久精品国产日本波多野结衣| 久久国产精品偷|