在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Interferon-induced GTP-binding protein Mx1 (Mx1)

Recombinant Mouse Interferon-induced GTP-binding protein Mx1 (Mx1)

  • 中文名稱：
    小鼠Mx1重組蛋白
  • 貨號：
    CSB-YP015249MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Mx1重組蛋白
  • 貨號：
    CSB-EP015249MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Mx1重組蛋白
  • 貨號：
    CSB-EP015249MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Mx1重組蛋白
  • 貨號：
    CSB-BP015249MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Mx1重組蛋白
  • 貨號：
    CSB-MP015249MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Mx1; Interferon-induced GTP-binding protein Mx1; Influenza resistance protein; Myxoma resistance protein 1; Myxovirus resistance protein 1
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-631
  • 氨基酸序列
    MDSVNNLCRH YEEKVRPCID LIDTLRALGV EQDLALPAIA VIGDQSSGKS SVLEALSGVA LPRGSGIVTR CPLVLKLRKL KEGEEWRGKV SYDDIEVELS DPSEVEEAIN KGQNFIAGVG LGISDKLISL DVSSPNVPDL TLIDLPGITR VAVGNQPADI GRQIKRLIKT YIQKQETINL VVVPSNVDIA TTEALSMAQE VDPEGDRTIG VLTKPDLVDR GAEGKVLDVM RNLVYPLKKG YMIVKCRGQQ DIQEQLSLTE AFQKEQVFFK DHSYFSILLE DGKATVPCLA ERLTEELTSH ICKSLPLLED QINSSHQSAS EELQKYGADI PEDDRTRMSF LVNKISAFNR NIMNLIQAQE TVSEGDSRLF TKLRNEFLAW DDHIEEYFKK DSPEVQSKMK EFENQYRGRE LPGFVDYKAF ESIIKKRVKA LEESAVNMLR RVTKMVQTAF VKILSNDFGD FLNLCCTAKS KIKEIRLNQE KEAENLIRLH FQMEQIVYCQ DQVYKETLKT IREKEAEKEK TKALINPATF QNNSQFPQKG LTTTEMTQHL KAYYQECRRN IGRQIPLIIQ YFILKTFGEE IEKMMLQLLQ DTSKCSWFLE EQSDTREKKK FLKRRLLRLD EARQKLAKFS D
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Interferon-induced dynamin-like GTPase with antiviral activity against influenza A virus, (IAV), influenza B virus (IBV) and Thogoto virus (THOV). Inhibits FLUAV by interfering with the process of primary transcription, probably by affecting the viral polymerase function.
  • 基因功能參考文獻：
    1. Genetic dominance of protective myxovirus (influenza virus) resistance 1 protein (Mx1) haplotypes was observed to differ by subspecies of origin. PMID: 29187420
    2. Our studies emphasize therefore that proper controls are crucial when modeling gene deletion using the Mx1-Cre transgene. PMID: 27373927
    3. the enhanced influenza virus susceptibility of CAST/EiJ mice can be explained by minor alterations in the MX1 restriction factor that negatively affect its enzymatic activity and reduce its half-life PMID: 27654285
    4. Data indicate that Mx protein as host defense peptide can be potentiated for improving influenza vaccine efficacy. PMID: 28027847
    5. Mouse Mx1 was shown to be essential for interferon type I-dependent protective immunity against primary influenza. (Review) PMID: 26761402
    6. In Mx1-intact mice with weakened resistance due to deficiencies in Mavs and Tlr7, an elevated respiratory bacterial burden was found. PMID: 27102485
    7. Functional Comparison of Mx1 from Two Different Mouse Species Reveals the Involvement of Loop L4 in the Antiviral Activity against Influenza A Viruses. PMID: 26292322
    8. we show that, very unexpectedly, congenic D2-Mx1(r/r) mice carrying the wild-type Mx1 gene from the A2G strain are not fully protected against lethal influenza virus infections PMID: 26202236
    9. dysregulated gene transcriptional activity corresponded to persistent induction of cytokine/chemokines and recruitment of cytokine-producing cells that promote inflammation in B6-Mx1(-/-) mouse lungs. PMID: 23395090
    10. Mice with a functional Mx1 generate a strong antiviral state by downregulating key modulator molecules associated with influenza virus lethality. PMID: 22190720
    11. functional Mx1 did not alter olfactory bulb invasion by virus but attenuated illness compared to knockout Mx1 mice PMID: 21821116
    12. nuclear MxA suppresses the influenza virus transcription by interacting not only with RNA polymerase subunit PB2 but also with influenza NP PMID: 14752052
    13. Thogoto virus mutant lacking protein ML was strongly attenuated in mice carrying the interferon-responsive Mx1 gene PMID: 15452266
    14. A variant of influenza A virus strain A/PR/8/34 (H1N1) exhibits normal sensitivity to growth restriction by Mx1; the virus is well controlled in Mx1-expressing but not Mx1-null mice. PMID: 17426143
    15. Mx1 represents a key component of the murine innate immune system that mediates protection against epidemic and pandemic influenza viruses. PMID: 17652381
    16. Our data support the hypothesis that Mx1 expression protects mice against the high pathogenicity of H5N1 virus through inhibition of viral polymerase activity ultimately resulting in reduced viral growth and spread PMID: 17700072
    17. Mx mice show resistance to the infection of influenza virus but not of West Nile virus. PMID: 19827744

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, perinuclear region.
  • 蛋白家族：
    TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
  • 數據庫鏈接：

    KEGG: mmu:17857

    UniGene: Mm.33996



主站蜘蛛池模板： 乱码av麻豆丝袜熟女系列| 三级特黄60分钟在线观看| 亚洲精品日本久久一区二区三区| 免费又黄又爽1000禁片| 人妻少妇乱子伦精品| 中文日产幕无线码6区收藏| 老色鬼永久精品网站| 亚洲综合av永久无码精品一区二区| 国产精品老熟女露脸视频| 大狠狠大臿蕉香蕉大视频| 国产欧美va天堂在线观看视频下载| 久碰久摸久看视频在线观看| 黑人狠狠的挺身进入| 国产精品亚洲mnbav网站| 色偷偷偷在线视频播放| 免费无码又爽又刺激高潮视频| 久久99热这里只有精品国产| 无码一区二区免费波多野播放搜索| 东京热无码av男人的天堂| 亚洲熟妇无码八av在线播放| 天天做天天躁天天躁| 成年女人永久免费看片| 国产亚洲精品影视在线| 天堂8在线新版官网| 亚洲国产av玩弄放荡人妇| 精品亚洲成av人在线观看| 亚洲美女又黄又爽在线观看| 色婷婷久久久swag精品| 国产精品毛片在线完整版| 欧美40老熟妇色xxxxx| 无码人妻aⅴ一区二区三区| 人妻精品久久久久中文字幕| 高清国产亚洲欧洲av综合一区| 国产欧美精品一区二区三区| 国产一区二区在线视频| 亚洲精品国产自在现线看| 国产杨幂av在线播放| 日本55丰满熟妇厨房伦| 无套内谢少妇毛片aaaa片免费| 亚洲乱色熟女一区二区三区丝袜| 日日躁夜夜躁狠狠躁超碰97|