在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Huntingtin-interacting protein 1-related protein (Hip1r), partial

Recombinant Mouse Huntingtin-interacting protein 1-related protein (Hip1r), partial

  • 中文名稱：
    小鼠Hip1r重組蛋白
  • 貨號：
    CSB-YP888346MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Hip1r重組蛋白
  • 貨號：
    CSB-EP888346MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Hip1r重組蛋白
  • 貨號：
    CSB-EP888346MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Hip1r重組蛋白
  • 貨號：
    CSB-BP888346MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Hip1r重組蛋白
  • 貨號：
    CSB-MP888346MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Hip1r
  • Uniprot No.：
  • 別名：
    Hip1rHuntingtin-interacting protein 1-related protein; HIP1-related protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Partial
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
  • 基因功能參考文獻：
    1. Specific expression of mHip1r in the embryonic brain and secretory glands suggests a possible role for Hip1r in normal development and in the pathology of HD. PMID: 24712472
    2. IFNgamma was required for the mucous cell hypertrophy and hyperplasia observed in Hip1r-deficient mice. IFNgamma is critical for the development of the gastric epithelial cell metaplasia that results from parietal cell atrophy in the Hip1r-deficient mice. PMID: 22525425
    3. This study characterized gastric gland development in wild-type and Hip1r-deficient mice to define normal development, as well as the timing and sequence of the cellular transformation events in the mutant stomach. PMID: 20813912
    4. mice deficient in both HIP1 and HIP1r have accelerated development of abnormalities seen in Hip1 -deficient mice, including kypholordosis and growth defects PMID: 15121852
    5. roles of Hip1 and Hip1R in affecting clathrin assembly and actin distribution are mediated by their interaction with the conserved sequence of clathrin light chains. PMID: 15533940
    6. Degenerative phenotypes seen in knockout mice are due mainly to HIP1 and HIP1r protein deficiency rather than altered expression of neighboring genes or disrupted intronic elements. PMID: 17452370
    7. Hip1r plays a significant role in gastric physiology, mucosal architecture, and secretory membrane dynamics in parietal cells. PMID: 18535670
    8. Actin binding by Hip1 (huntingtin-interacting protein 1) and Hip1R (Hip1-related protein) is regulated by clathrin light chain PMID: 18790740

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane. Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region.
  • 蛋白家族：
    SLA2 family
  • 組織特異性：
    Widely expressed. Expressed at lower levels in skeletal muscle and heart. The level of expression does not change appreciably during development.
  • 數據庫鏈接：


主站蜘蛛池模板： 国内高清久久久久久| 国产9色在线 | 日韩| 天天做天天爱天天爽综合网| 天天爱天天做天天做天天吃中文 | 超清精品丝袜国产自在线拍| 国偷自产视频一区二区久| 国产一区二区精品丝袜| 最新色国产精品精品视频| 欧美亚洲另类丝袜综合网| а天堂中文在线官网在线| 精品少妇人妻av一区二区| 国产voyeur精品偷窥222| 欧美日产欧美日产国产精品| 国产精品无套呻吟在线| 国产激情无码一区二区三区| 人人妻人人爽人人做夜欢视频九色| av性色在线乱叫| 欧美激情a∨在线视频播放| 欧美成人一区二免费视频| 变态另类先锋影音| 亚洲熟妇无码av不卡在线| 亚洲色大成网站久久久| 人妻 日韩精品 中文字幕| 精品久久久久久无码人妻蜜桃| 好爽太紧了舒服视频| 377p欧洲日本亚洲大胆| 国产精品久久无码一区二区三区网| 久久精品国产精品久久久| 亚洲熟妇av日韩熟妇av| 亚洲熟女www一区二区三区| 无码人妻丰满熟妇区毛片| 亚洲精品无码久久久久av老牛| 性高湖久久久久久久久| 国产产区一二三产区区别在线 | 我和亲妺妺乱的性视频| 巨胸喷奶水视频www免费网站| 国产精品玖玖玖在线| 国产自产v一区二区三区c| 日日噜噜夜夜狠狠久久无码区| 国产山东熟女48嗷嗷叫| 亚洲人妻av伦理|