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  4. Recombinant Mouse Homeobox protein SIX6 (Six6)

Recombinant Mouse Homeobox protein SIX6 (Six6)

  • 中文名稱：
    小鼠Six6重組蛋白
  • 貨號(hào)：
    CSB-YP889899MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Six6重組蛋白
  • 貨號(hào)：
    CSB-EP889899MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Six6重組蛋白
  • 貨號(hào)：
    CSB-EP889899MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Six6重組蛋白
  • 貨號(hào)：
    CSB-BP889899MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Six6重組蛋白
  • 貨號(hào)：
    CSB-MP889899MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Six6
  • Uniprot No.：
  • 別名：
    Six6; Optx2; Six9; Homeobox protein SIX6; Optic homeobox 2; Sine oculis homeobox homolog 6; Six9 protein
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達(dá)區(qū)域：
    1-246
  • 氨基酸序列
    MFQLPILNFS PQQVAGVCET LEESGDVERL GRFLWSLPVA PAACEALNKN ESVLRARAIV AFHGGNYREL YHILENHKFT KESHAKLQAL WLEAHYQEAE KLRGRPLGPV DKYRVRKKFP LPRTIWDGEQ KTHCFKERTR HLLREWYLQD PYPNPSKKRE LAQATGLTPT QVGNWFKNRR QRDRAAAAKN RLQQQVLSQG PGRVLRSEGE GTPEVLGVAS SPAASLSSKA ATSAISITSS DSECDI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in eye development.
  • 基因功能參考文獻(xiàn)：
    1. Six6-null mice display abnormal patterns of circadian behavior. PMID: 23382588
    2. SoxB1 transcription factors are direct activators of Six6 expression in the ventral forebrain PMID: 22561201
    3. Six6 plays an important role in the regulation of GnRH expression and hypothalamic control of fertility. PMID: 21228153
    4. in association with Dach corepressors, regulates proliferation of retinal and pituitary precursor cells by directly repressing cyclin-dependent kinase inhibitors, including the p27Kip1 promoter PMID: 12130660
    5. Results show that Lhx2 and Pax6 transcription factors operate in a concerted manner during retinal development to promote transcriptional activation of the Six6 homeobox-gene in primitive and mature retinal progenitors. PMID: 19146846

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  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    SIX/Sine oculis homeobox family
  • 組織特異性：
    In the developing embryo, expressed mainly in the ventral optic stalk, optic chiasma, the neural retina and the primordial tissues that give rise to the pituitary/hypothalamus axis. Not expressed in the lens placode.
  • 數(shù)據(jù)庫鏈接：


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