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  4. Recombinant Mouse Homeobox protein Nkx-6.3 (Nkx6-3)

Recombinant Mouse Homeobox protein Nkx-6.3 (Nkx6-3)

  • 中文名稱：
    小鼠Nkx6-3重組蛋白
  • 貨號：
    CSB-YP666263MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Nkx6-3重組蛋白
  • 貨號：
    CSB-EP666263MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Nkx6-3重組蛋白
  • 貨號：
    CSB-EP666263MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Nkx6-3重組蛋白
  • 貨號：
    CSB-BP666263MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Nkx6-3重組蛋白
  • 貨號：
    CSB-MP666263MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Nkx6-3
  • Uniprot No.：
  • 別名：
    Nkx6-3; Homeobox protein Nkx-6.3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-262
  • 氨基酸序列
    MESNLQGTFL LNNTQLAQFS EMKAPMCQYS VQNSFYKLSP PGLGPQLAAG TPHGITDILS RPVATPNSSL LSGYPHVAGF GGLSSQGVYY GPQVGSFSKA GNEYPTRTRN CWADTGQDWR GSARPCSNTP DPLSDTIHKK KHTRPTFTGH QIFALEKTFE QTKYLAGPER ARLAYSLGMT ESQVKVWFQN RRTKWRKKSA LEPSSSTPRA PGGASGDRAA SENEDDEYNK PLDPDSDDEK IRLLLRKHRA AFSVLSLGAH SV
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Putative transcription factor, which may be involved in patterning of central nervous system and pancreas.
  • 基因功能參考文獻：
    1. Thus, cross-antagonism between Nkx6 and Ptf1a in multipotent progenitors governs the equilibrium between endocrine and acinar cell neogenesis required for normal pancreas development. PMID: 20627083
    2. Nkx6.3 shows a remarkably selective expression in a subpopulation of differentiating V2 neurons at caudal hindbrain levels. PMID: 16326147
    3. Nkx6.3 transcripts localize in the epithelium of the most distal stomach region, the antrum and pylorus; expression in the adult intestine is lower and confined to the proximal duodenum. PMID: 18347062
    4. Nkx6.3 function is dispensable for CNS development and lead to the proposal that absence of overt defects is due to functional compensation from a related homeodomain transcription factor. PMID: 18586225
  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in the developing CNS and gastro-intestinal tract.
  • 數據庫鏈接：


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