在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Heterogeneous nuclear ribonucleoprotein L-like (Hnrpll)

  • 中文名稱:
    小鼠Hnrnpll重組蛋白
  • 貨號(hào):
    CSB-YP010630MO
  • 規(guī)格:
  • 來(lái)源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Hnrnpll重組蛋白
  • 貨號(hào):
    CSB-EP010630MO-B
  • 規(guī)格:
  • 來(lái)源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Hnrnpll重組蛋白
  • 貨號(hào):
    CSB-BP010630MO
  • 規(guī)格:
  • 來(lái)源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Hnrnpll重組蛋白
  • 貨號(hào):
    CSB-MP010630MO
  • 規(guī)格:
  • 來(lái)源:
    Mammalian cell
  • 其他:

產(chǎn)品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Hnrnpll
  • Uniprot No.:
  • 別名:
    Hnrnpll; HnrpllHeterogeneous nuclear ribonucleoprotein L-like
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度:
    full length protein
  • 表達(dá)區(qū)域:
    1-591
  • 氨基酸序列
    MSSSSSSSPK EETYEEDREF ESQAKRLKTE EGEIVYSAEE SENRQEATPQ AGSDSDSGGG DGGDGDGGSG GGGDGEEGEG GEEGDEGDGD EGGSGGDEGG SGGGPRSMPL STEGGGSHHK VSVSPVVHVR GLCESVVEAD LVEALEKFGT ICYVMMMPFK RQALVEFENI DSAKECVTFA ADVPVYIAGQ QAFFNYSTSK RITRPGNTDD PSGGNKVLLL SIQNPLYPIT VDVLYTVCNP VGKVQRIVIF KRNGIQAMVE FESVLCAQKA KAALNGADIY AGCCTLKIEY ARPTRLNVIR NDNDSWDYTK PYLGRRDRGK GRQRQAILGD HPSSFRHDGY GSHGPLLPLP SRYRMGSRDT PELVAYPLPQ ASSSYMHGGS PSGSVVMVSG LHQLKMNCSR VFNLFCLYGN IEKVKFMKTI PGTALVEMGD EYAVERAVTH LNNVKLFGKR LNVCVSKQHS VVPSQIFELE DGTSSYKDFA MSKNNRFTSA GQASKNIIQP PSCVLHYYNV PLCVTEETFT KLCNDHEVLP FIKYKVFDAK ASAKTLSGLL EWKCKTDAVE ALTALNHYQI RVPNGSNPYT LKLCFSTSSH L
  • 蛋白標(biāo)簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式:
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng):
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
  • 基因功能參考文獻(xiàn):
    1. HNRNPLL is a novel metastasis suppressor of colorectal cancer, and modulates alternative splicing of CD44 during epithelial-mesenchymal transition. PMID: 28360095
    2. Data suggest that hnRNPLL specifically associates with cytoplasmic PABPC1 in both T-lymphocytes and plasma cells; PABPC1 promotes binding of hnRNPLL to immunoglobulin H (IgH, heavy chain) mRNA and regulates switching from mIgH (membrane isoform) to sIgH (secreted isoform) in plasma cells. (hnRNPLL = heterogeneous nuclear ribonucleoprotein L-like protein; PABPC1 = cytoplasmic poly[A]-binding protein 1) PMID: 28611064
    3. We identify similar patterns of hnRNPLL-induced differential intron retention flanking alternative exons in 14 other genes, representing novel elements of the hnRNPLL-induced splicing program in T cells. PMID: 24476532
    4. Data indicate that the RNA-binding protein hnRNPLL has a critical role in tuning transcriptomes of terminally differentiating B lymphocytes. PMID: 25825742
    5. The splicing factor hnRNPLL and the transcription elongation factor ELL2 modulate the ratio of secred versus membrane-encoding Ighg2b transcripts at the expense of the secreted isoform. PMID: 22991471
    6. results highlight both overlapping and divergent roles for hnRNPLL between conventional T cells and NKT cells PMID: 22073166
    7. In T cells with no CD45 protein, hnRNPLL mutation diminishes peripheral T cell accumulation and demonstrates that hnRNPLL regulates T cell longevity independently from its effects on CD45 splicing. PMID: 20505149
    8. A single substitution in a memory-induced RNA-binding protein, hnRNPLL, destabilized an RNA-recognition domain that bound with micromolar affinity to RNA containing the Ptprc exon-silencing sequence. PMID: 19100700

    顯示更多

    收起更多

  • 數(shù)據(jù)庫(kù)鏈接:


主站蜘蛛池模板: 精品亚洲成a人片在线观看| 精品久久久久国产免费| 日产精品高潮呻吟av久久| 国精品99久9在线 | 免费| 亚洲色在线无码国产精品| 玖玖资源站无码专区| 国产精品人人做人人爽| 久久午夜无码鲁丝片午夜精品| 国产精品美女www爽爽爽视频 | 久久亚洲春色中文字幕久久久 | 久久97国产超碰青草| 国产360激情盗摄全集| 午夜无码人妻av大片色欲| xx性欧美肥妇精品久久久久久| 色先锋资源久久综合5566| 亚洲视频高清不卡在线观看| 日韩精品久久久久久免费| 奇米影视888欧美在线观看| 国产在线不卡视频免费视频| h人成在线看免费视频| 午夜天堂一区人妻| 99久久婷婷国产综合精品| yyyy11111少妇影院| 久热在线播放中文字幕| 亚洲另类春色校园小说| 国产日产欧产精品| 亚洲国产成人精品无码区蜜柚| 日韩精品成人一区二区三区| 解开人妻的裙子猛烈进入| 亚洲精品国产精品国产自2022| 动漫精品视频一区二区三区| 少妇系列之白嫩人妻| 中国国产免费毛卡片| 丁香五月激情综合亚洲| 人妻人人做人碰人人添| 美女内射视频www网站午夜| 97人妻免费碰视频碰免| 人妻激情文学| 国产精品久久久久久妇女| 久久爱www人成狠狠爱综合网| 欧美自拍另类欧美综合图片区 |