在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Guanylate cyclase soluble subunit alpha-3 (Gucy1a3)

Recombinant Mouse Guanylate cyclase soluble subunit alpha-3 (Gucy1a3)

  • 中文名稱：
    小鼠Gucy1a1重組蛋白
  • 貨號：
    CSB-YP861695MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gucy1a1重組蛋白
  • 貨號：
    CSB-EP861695MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gucy1a1重組蛋白
  • 貨號：
    CSB-EP861695MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gucy1a1重組蛋白
  • 貨號：
    CSB-BP861695MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gucy1a1重組蛋白
  • 貨號：
    CSB-MP861695MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Gucy1a1; Gucy1a3Guanylate cyclase soluble subunit alpha-1; GCS-alpha-1; EC 4.6.1.2; Guanylate cyclase soluble subunit alpha-3; GCS-alpha-3; Soluble guanylate cyclase large subunit
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-691
  • 氨基酸序列
    MFCRKFKDLK ITGECPFSLL APGQVPKEPT EEVAGGSEGC QATLPICQYF PEKNAEGSLP QRKTSRNRVY LHTLAESICK LIFPECERLN LALQRTLAKH KIEENRKSSE KEDLEKIIAE EAIAAGAPVE ALKDSLGEEL FKICYEEDEH ILGVVGGTLK DFLNSFSTLL KQSSHCQEAE RRGRLEDASI LCLDKDQDFL NVYYFFPKRT TALLLPGIIK AAARILYESH VEVSLMPPCF RSDCTEFVNQ PYLLYSVHVK STKPSLSPGK PQSSLVIPAS LFCKTFPFHF MLDRDLAILQ LGNGIRRLVN KRDFQGKPNF EEFFEILTPK INQTFSGIMT MLNMQFVIRV RRWDNSVKKS SRVMDLKGQM IYIVESSAIL FLGSPCVDRL EDFTGRGLYL SDIPIHNALR DVVLIGEQAR AQDGLKKRLG KLKATLEHAH QALEEEKKRT VDLLCSIFPS EVAQQLWQGQ IVQAKKFSEV TMLFSDIVGF TAICSQCSPL QVITMLNALY TRFDQQCGEL DVYKVETIGD AYCVAGGLHR ESDTHAVQIA LMALKMMELS NEVMSPHGEP IKMRIGLHSG SVFAGVVGVK MPRYCLFGNN VTLANKFESC SVPRKINVSP TTYRLLKDCP GFVFTPRSRE ELPPNFPSDI PGICHFLDAY HHQGPNSKPW FQDKDVEDGN ANFLGKASGI D
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 基因功能參考文獻：
    1. Exogenous or paracrine sources of NO promote the specification towards the myocyte lineage and expression of cardiac sarcomeric proteins of adult cardiac progenitor cells. This is contingent upon the expression and activity of the alpha1 subunit of guanylyl cyclase in CPC that is necessary for NO-mediated inhibition of the canonical Wnt/beta-catenin pathway. PMID: 27520736
    2. These data demonstrate that a reduction in cardiac sGC activity worsens doxorubicin-induced cardiotoxicity in mice and identify sGC as a potential therapeutic target. PMID: 27505125
    3. We suggest that Gucy1a3 activity promotes the phenotypic switching of smooth muscle cells from a contractile to a synthetic state, fostering the formation of atherosclerosis. PMID: 27315776
    4. The authors elucidated this dependency by showing that guanylate cyclase-1 is a novel rhodopsin-binding protein. PMID: 26590321
    5. Cellular markers revealed that vascular SMC differentiation decreased, whereas myofibroblast activation increased in the hyperoxic sGC-alpha1 KO pup lung. PMID: 23934926
    6. Soluble guanylate cyclase alpha1-deficient mice: a novel murine model for primary open angle glaucoma. PMID: 23527308
    7. Male mice deficient in a NO receptor component, the alpha1 subunit of soluble guanylate cyclase (sGCalpha1), are prone to hypertension in some, but not all, mouse strains, suggesting that additional genetic factors contribute to the onset of hypertension PMID: 22565307
    8. results show that the loss of sGCalpha1 has a positive inotropic and lusitropic effect on basal cardiac function, indicating an important role for sGCalpha1 in regulating basal myocardial contractility PMID: 21394564
    9. RD3 mediates the export of GC1 from the endoplasmic reticulum to endosomal vesicles, and that the C terminus of GC1 is required for RD3 binding PMID: 21078983
    10. Requirement of both alpha-2 and alpha-1 guanylate cyclases for signaling in long-term potentiation (LTP) indicates the existence of two distinct nitric oxide/cGMP-mediated pathways, which have to work in concert for expression of LTP. PMID: 17251421
    11. sGCalpha1 is essential for NO-mediated pulmonary vasodilation and limits chronic hypoxia-induced pulmonary vascular remodeling PMID: 17679618
    12. guanylate cyclase has a role in pulmonary arterial hypertension PMID: 18550612
    13. NFATc3 and HuR are important regulators of sGC-alpha1 expression in pulmonary vascular smooth muscle cells during chronic hypoxia-induced pulmonary hypertension. PMID: 19592461

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Adenylyl cyclase class-4/guanylyl cyclase family
  • 數據庫鏈接：


主站蜘蛛池模板： 国产色综合天天综合网| 人人婷婷人人澡人人爽| 欧美 日产 国产在线观看| 久久婷婷五月综合色俺也想去 | 精品欧美小视频在线观看| 国产成_人_综合_亚洲_国产| 国产又粗又猛又爽又黄| 国产成人无码性教育视频| 日韩精品久久久久久久电影蜜臀| 精品自拍亚洲一区在线| av无码人妻波多野结衣| 亚洲va成无码人在线观看天堂| 少妇做爰免费视频了| 国产精品无码av天天爽| 亚洲性色成人av| 久久国产乱子伦精品免费台湾| 虎白女粉嫩尤物福利视频| 黑人大战亚洲人精品一区| 日韩人妻无码一区二区三区综合| 日韩欧美精品有码在线| 茄子视频国产在线观看| 中文字幕日韩欧美一区二区三区| 醉酒后少妇被疯狂内射视频| 亚洲国产精品无码7777一线| 2023国产精品一卡2卡三卡4卡| 内射白浆一区二区在线观看| 中文在线中文资源| 国产精品国产自线拍免费不卡| 中文字幕av伊人av无码av狼人| 国产成人a人亚洲精v品无码| 东京热一区二区三区无码视频 | 2021精品国产自在现线看| 中文字幕精品久久久久人妻| 风流老熟女一区二区三区| 国产在线看片免费视频| 天天天天躁天天爱天天碰| 麻豆一区二区在我观看| 国产伦精品一区二区三区| 国产成人av国语在线观看| 无码抽搐高潮喷水流白浆| 亚洲国产欧美在线观看|