在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Glutaminyl-peptide cyclotransferase (Qpct)

In Stock
  • 中文名稱:
    小鼠Qpct重組蛋白
  • 貨號:
    CSB-MP019135MO
  • 規格:
    ¥3000
  • 圖片:
    • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • 其他:

產品詳情

  • 純度:
    Greater than 90% as determined by SDS-PAGE.
  • 基因名:
    Qpct
  • Uniprot No.:
  • 別名:
    Qpct; Glutaminyl-peptide cyclotransferase; EC 2.3.2.5; Glutaminyl cyclase; QC; Glutaminyl-tRNA cyclotransferase
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Full Length of Mature Protein
  • 來源:
    Mammalian cell
  • 分子量:
    41.6kDa
  • 表達區域:
    36-362aa
  • 氨基酸序列
    AWTQEKNHHQPAHLNSSSLQQVAEGTSISEMWQNDLRPLLIERYPGSPGSYSARQHIMQRIQRLQAEWVVEVDTFLSRTPYGYRSFSNIISTLNPEAKRHLVLACHYDSKYFPRWDSRVFVGATDSAVPCAMMLELARALDKKLHSLKDVSGSKPDLSLRLIFFDGEEAFHHWSPQDSLYGSRHLAQKMASSPHPPGSRGTNQLDGMDLLVLLDLIGAANPTFPNFFPKTTRWFNRLQAIEKELYELGLLKDHSLERKYFQNFGYGNIIQDDHIPFLRKGVPVLHLIASPFPEVWHTMDDNEENLHASTIDNLNKIIQVFVLEYLHL
    Note: The complete sequence may include tag sequence, target protein sequence, linker sequence and extra sequence that is translated with the protein sequence for the purpose(s) of secretion, stability, solubility, etc.
    If the exact amino acid sequence of this recombinant protein is critical to your application, please explicitly request the full and complete sequence of this protein before ordering.
  • 蛋白標簽:
    N-terminal 6xHis-Myc-tagged
  • 產品提供形式:
    Liquid or Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 緩沖液:
    If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
    Note: If you have any special requirement for the glycerol content, please remark when you place the order.
    If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    3-7 business days
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet & COA:
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Responsible for the biosynthesis of pyroglutamyl peptides. Has a bias against acidic and tryptophan residues adjacent to the N-terminal glutaminyl residue and a lack of importance of chain length after the second residue.
  • 基因功能參考文獻:
    1. Authors identified a placenta-specific imprinted gene Qpct. Results show that Qpct is widely expressed during early embryonic development and can be detected in the telencephalon, midbrain, and rhombencephalon at E9.5-E11.5. PMID: 26447138
    2. co-regulation of the enzyme glutaminyl cyclase and its substrate TRH was reflected by a co-induction of both proteins in reactive astrocytes in proximity of Abeta deposits PMID: 25446989
    3. This study provide a thorough comparative characterization of the glutaminyl cyclases QC and isoQC in defined brain regions of different inbred and outbred mouse strains PMID: 24886834
    4. This study presents a first comparison of two mammalian QCs (mouse and human)containing typical, conserved post-translational modifications. PMID: 21671571
    5. Glutaminyl cyclase in a mouse knockout model has a role in hypothyroidism but not hypogonadism PMID: 21330373
    6. QC is crucial for modulating AbetapE3-42 levels in vivo and prove on a genetic base the concept that reduction of QC activity is a promising new therapeutic approach for AD. PMID: 21148560
    7. Murine isoQC proteins displayed a broad substrate specificity and preference for hydrophobic substrates, similar to the related QC. PMID: 19804409
    8. Results describe the expression of glutaminyl cyclase throughout the mouse brain during early postnatal development. PMID: 19699792
    9. The observations of this study indicated that brain ischemia might be a pathogenic factor of alzheimer disease through increasing BACE1, cathepsin B, and glutaminyl cyclase. PMID: 19809370
    10. QC is a zinc-dependent catalyst PMID: 16201766

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Glutaminyl-peptide cyclotransferase family
  • 數據庫鏈接:


主站蜘蛛池模板: 国产无吗一区二区三区在线欢| 欧美成aⅴ人高清怡红院| 五月综合缴情婷婷六月| 日本无码人妻一区二区色欲 | 欧美精欧美乱码一二三四区| 长腿校花无力呻吟娇喘的视频| 国产高清av首播原创麻豆| 国内精品九九久久久精品| 人妻无码手机在线中文| 与子敌伦刺激对白播放| 2020精品国产自在现线看| 国产成人一区二区精品视频 | 亚洲成av人片在www| 99久久国产露脸精品竹菊传媒| 巨人精品福利官方导航| 娇小萝被两个黑人用半米长| 国产精品久久无码不卡黑寡妇| 国产精品调教视频一区| 久久99精品久久久久久水蜜桃| 亚洲欧洲日产国码久在线| 国产乱人伦偷精品视频aaa| 国产精品久久久久蜜芽| 日本成aⅴ人片日本伦| 国产精品一区波多野结衣| 国产成人av性色在线影院色戒| 香蕉久久国产av一区二区| 中国女人内射6xxxxx| 色妺妺免费影院| 四虎精品成人a在线观看| 欧美激情在线播放| 国产精品女上位好爽在线| 久久久久久亚洲综合影院| 国产乱子伦农村xxxx| 色欲av无码一区二区三区| 精品一卡2卡三卡4卡乱码精品视频| 特级毛片a片久久久久久| 熟女少妇内射日韩亚洲| 久久精品人人做人人爽老司机| 亚洲精品中国国产嫩草影院美女| 狠狠色狠狠色综合日日不卡 | 国产亚洲另类无码专区|