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  4. Recombinant Mouse Glia maturation factor beta (Gmfb)

Recombinant Mouse Glia maturation factor beta (Gmfb)

  • 中文名稱：
    小鼠Gmfb重組蛋白
  • 貨號：
    CSB-YP880404MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Gmfb重組蛋白
  • 貨號：
    CSB-EP880404MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Gmfb重組蛋白
  • 貨號：
    CSB-EP880404MO-B
  • 說明書：
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Gmfb重組蛋白
  • 貨號：
    CSB-BP880404MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Gmfb重組蛋白
  • 貨號：
    CSB-MP880404MO
  • 說明書：
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Gmfb
  • Uniprot No.：
  • 別名：
    GmfbGlia maturation factor beta; GMF-beta
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達(dá)區(qū)域：
    2-142
  • 氨基酸序列
    SESLVVCDV AEDLVEKLRK FRFRKETHNA AIIMKIDKDE RLVVLDEELE GVSPDELKDE LPERQPRFIV YSYKYQHDDG RVSYPLCFIF SSPVGCKPEQ QMMYAGSKNK LVQTAELTKV FEIRNTEDLT EEWLREKLGF FH
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點(diǎn)詳情

  • 功能：
    This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells.
  • 基因功能參考文獻(xiàn)：
    1. This is the first study to demonstrate the expression of GMF-beta in reactive glial cells and its association with neuropathology in toxoplasmic encephalitis. PMID: 28774213
    2. GMF transgenic mice might be a novel mouse model of accelerated aging, due to the abnormal lamin A PMID: 26232943
    3. Deficiency of glia maturation factor protects the dopaminergic neuron loss in a model of parkinsonism. PMID: 25754447
    4. The data suggest that debranching by GMFbeta plays an important role in branched actin regulation, lamellipodial dynamics, and directional migration. PMID: 26101216
    5. [glial maturation factor; GMF] Results imply that GMF is involved in the signaling leading to the activation of glycogen synthase kinase-3beta and caspase-3 in N18 cells and strongly suggest its involvement in neurodegeneration. PMID: 18054898
    6. proteinuria induction of GMF-beta in renal proximal tubular cells may play a critical role in the progression of renal diseases by enhancing oxidative injuries PMID: 12791701

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  • 蛋白家族：
    Actin-binding proteins ADF family, GMF subfamily
  • 數(shù)據(jù)庫鏈接：


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