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  4. Recombinant Mouse Galectin-2 (Lgals2)

Recombinant Mouse Galectin-2 (Lgals2)

  • 中文名稱：
    小鼠Lgals2重組蛋白
  • 貨號：
    CSB-YP866594MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Lgals2重組蛋白
  • 貨號：
    CSB-EP866594MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Lgals2重組蛋白
  • 貨號：
    CSB-EP866594MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Lgals2重組蛋白
  • 貨號：
    CSB-BP866594MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Lgals2重組蛋白
  • 貨號：
    CSB-MP866594MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Lgals2
  • Uniprot No.：
  • 別名：
    Lgals2; Galectin-2; Gal-2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-130
  • 氨基酸序列
    MSEKFEVKDL NMKPGMSLKI KGKIHNDVDR FLINLGQGKE TLNLHFNPRF DESTIVCNTS EGGRWGQEQR ENHMCFSPGS EVKITITFQD KDFKVTLPDG HQLTFPNRLG HNQLHYLSMG GLQISSFKLE
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    This protein binds beta-galactoside. Its physiological function is not yet known.
  • 基因功能參考文獻：
    1. analysis of the effect of low-temperature plasma on the expression of galectin-1, -2, and -3 in the healing skin compared with those of electrocoagulation conducted with a high-frequency electrical coagulator PMID: 26827730
    2. Therefore, Cys(57) is suggested to be responsible for oxidative inactivation of the mGal-2 protein, and protection of the sulfhydryl group of the Cys(57) in mGal-2 by S-nitrosylation is likely important for maintaining mGal-2 protein function in an oxidative environment such as the gastrointestinal tract. PMID: 27122052
    3. Studies of specific knock-out mice show that galectin-2 acts through the CD14/toll-like receptor (TLR)-4 pathway. It leads to increased CD40-positive and reduced CD206-positive macrophages around remodeling collateral arteries. PMID: 25884209
    4. Gal-2 oxidation by H2O2 resulted in the loss of sugar-binding ability, while S-nitrosylation prevented H2O2-inducted inactivation, presumably by protecting the Cys residue(s) in the protein. PMID: 25619132
    5. A comparative profiling has been started in the mouse as a model organism, combining sequence analysis, expression patterns and structural features in the cases of the homodimeric galectins-1, -2 and -7. PMID: 17706016
    6. Galectin-2 was present in nuclei of murine 3T3 fibroblasts. PMID: 17999373
    7. In normal murine skin, low levels of galectin-2 messenger RNA are detected. PMID: 19380789

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