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  4. Recombinant Mouse Four and a half LIM domains protein 5 (Fhl5)

Recombinant Mouse Four and a half LIM domains protein 5 (Fhl5)

  • 中文名稱：
    小鼠Fhl5重組蛋白
  • 貨號：
    CSB-YP892979MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Fhl5重組蛋白
  • 貨號：
    CSB-EP892979MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Fhl5重組蛋白
  • 貨號：
    CSB-EP892979MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Fhl5重組蛋白
  • 貨號：
    CSB-BP892979MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Fhl5重組蛋白
  • 貨號：
    CSB-MP892979MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Fhl5
  • Uniprot No.：
  • 別名：
    Fhl5; ActFour and a half LIM domains protein 5; FHL-5; Activator of cAMP-responsive element modulator in testis; Activator of CREM in testis
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-284
  • 氨基酸序列
    MTSSQFDCQY CTSSLIGKKY VLKDDNLYCI SCYDRIFSNY CEQCKEPIES DSKDLCYKNR HWHEGCFRCN KCHHSLVEKP FVAKDDRLLC TDCYSNECSS KCFHCKRTIM PGSRKMEFKG NYWHETCFVC EHCRQPIGTK PLISKESGNY CVPCFEKEFA HYCNFCKKVI TSGGITFRDQ IWHKECFLCS GCRKELYEEA FMSKDDFPFC LDCYNHLYAK KCAACTKPIT GLRGAKFICF QDRQWHSECF NCGKCSVSLV GEGFLTHNME ILCRKCGSGA DTDA
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    May be involved in the regulation of spermatogenesis. Stimulates CREM transcriptional activity in a phosphorylation-independent manner.
  • 基因功能參考文獻：
    1. Results indicate that SPAG8 acts as a regulator of ACT and plays an important role in CREM-ACT-mediated gene transcription during spermatogenesis. PMID: 20488182
    2. Fhl5 is not essential for testicular gene expression to a level detected by microarray-based measurements. PMID: 19930692
    3. ACT selectively associates with KIF17b, a kinesin highly expressed in male germ cells; The ACT-KIF17b interaction is restricted to specific stages of spermatogenesis and directly determines the intracellular localization of ACT PMID: 12493914
    4. Results indicate that numerous postmeiotic genes under CREM (cAMP-responsive element modulator) control require the coactivator function of ACT (activator of CREM) in testis. PMID: 15247423
  • 亞細胞定位：
    Nucleus. Note=Nuclei of round and elongated spermatids.
  • 組織特異性：
    Testis-specific, temporal expression is coordinated with CREM.
  • 數據庫鏈接：


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