在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Forkhead box protein N4 (Foxn4)

Recombinant Mouse Forkhead box protein N4 (Foxn4)

  • 中文名稱：
    小鼠Foxn4重組蛋白
  • 貨號：
    CSB-YP818349MO
  • 說明書：
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Foxn4重組蛋白
  • 貨號：
    CSB-EP818349MO
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Foxn4重組蛋白
  • 貨號：
    CSB-EP818349MO-B
  • 說明書：
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Foxn4重組蛋白
  • 貨號：
    CSB-BP818349MO
  • 說明書：
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Foxn4重組蛋白
  • 貨號：
    CSB-MP818349MO
  • 說明書：
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Foxn4
  • Uniprot No.：
  • 別名：
    Foxn4Forkhead box protein N4
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-521
  • 氨基酸序列
    MIESGIWSRM SEMIRSSGHS HHCSPQEYRF LPPVGDDDLP GDLQSLSWLT AVDVPRLQQM ANGRIDLGSS GVTHPHPGAL AGTADLHVGA APRPLLRRSQ TAVVPRGVLG LSPIGNHRAS AEQMNQFPAG GQASSGLQEM PQLYSPATQI PFPLPLGSQQ CPPAGLYGSP FSARPSYPQA HGAMHASQEP HPKHYPKPIY SYSCLIAMAL KNSKTGSLPV SEIYSFMKEH FPYFKTAPDG WKNSVRHNLS LNKCFEKVET KSSGSSRKGC LWALNLARID KMEEEMHKWK RKDLAAIHRS MANPEELDKL ISDRPESCRR PGKRGEPKAP MLTHATTVAM AHSCLAISQL PPKPLMTLSL QSVPLHHQLQ PQAHLAPDSP APAQTPPLHA LPSLSPGPLP QPAMGRVPGD FLNINSDMNT EVDALDPSIM DFALQGNLWE EMKEDSFSLD TLEAFGDSPL GCDLGAPSLT PVSGNSDQSF PDVQVTGLYA AYSTAADGVA PSAANSAQYL GTPGNKPIAL L
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development.
  • 基因功能參考文獻：
    1. the mosaic expression of Foxn4 and proneural factors may serve as the trigger to initiate asymmetric Dll4-Notch and subsequent BMP/TGFbeta signaling events required for neuronal diversity in the V2 domain. PMID: 24257627
    2. Mouse Foxn4 transfection reduced by 2.7-fold the basal level of Tbx2 promoter transcription, but deletion of the AD domain increased transcription showing that this domain might be a transregulatory domain. PMID: 21701787
    3. Foxn4 has an intrinsic activity to suppress the alternative photoreceptor cell fates of early retinal progenitors by selectively activating Dll4-Notch signaling. PMID: 22323600
    4. Foxn4 may have a non-cell-autonomous role critical for alveologenesis during lung development. PMID: 21438071
    5. findings show that Foxn4 is required for proper outgrowth of retinal ganglion cell (RGC) axons in vivo, suggesting a role for an amacrine cell-RGC interaction in axon growth PMID: 21334440
    6. Foxn4 acts synergistically with Mash1 to specify subtype identity of V2 interneurons in the spinal cord. PMID: 16020526
    7. Foxn4 induces expression of delta-like 4 (Dll4) and Mash1 (Ascl1). Dll4 then signals through Notch1 to subdivide the p2 progenitor pool in the ventral spinal cord. PMID: 17728344
    8. expressed during neural development in the retina, the ventral hindbrain and spinal cord and dorsal midbrain PMID: 11520680

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Mainly expressed in proliferator progenitor cells in brain and retina rather than differentiated cells. In contrast, is expressed only in postmitotic epithelial cells rather than in proliferative progenitors in the proximal airway.
  • 數據庫鏈接：


主站蜘蛛池模板： 黑人玩弄人妻中文在线| 高清国产一区二区三区在线| 麻豆视传媒精品av| 男人边做边吃奶头视频| 午夜伦4480yy私人影院| 久久毛片免费看一区二区三区| 精品无码国产自产在线观看水浒传| 国产高清无密码一区二区三区| 熟女内射v888av| 亚洲综合在线另类色区奇米| 日韩高清成片免费视频| 国产精品∧v在线观看| 国产无遮挡aaa片爽爽| 欧美xxxxx高潮喷水麻豆| 在线v片免费观看视频| 亚洲乱色熟女一区二区三区丝袜 | 亚洲 丝袜 制服 欧美 另类 | 中国丰满熟妇av| 日本边添边摸边做边爱| 成 人影片 免费观看| 在线播放免费人成毛片试看| 亚洲va中文字幕无码一二三区| 欧美人与性动交ccoo| 国产精品久久久久久久久久久久午衣片 | 国产成人av在线播放影院| 国产杨幂av在线播放| 娇妻玩4p被三个男人伺候电影| 综合在线 亚洲 成人 欧美| 人妻少妇久久精品电影| 国产精品免费福利久久| 性夜夜春夜夜爽aa片a | 人妻洗澡被强公日日澡电影 | 欧美性xxxxx极品老少| 天天躁日日躁狠狠躁| 色偷偷www.8888在线观看| 自拍偷自拍亚洲精品牛影院| 无码成人一区二区三区| 国产性猛交普通话对白| 少妇爆乳无码专区网站| 97高清国语自产拍| 久热国产vs视频在线观看|