在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Forkhead box protein D3 (Foxd3)

Recombinant Mouse Forkhead box protein D3 (Foxd3)

  • 中文名稱：
    小鼠Foxd3重組蛋白
  • 貨號：
    CSB-YP717193MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Foxd3重組蛋白
  • 貨號：
    CSB-EP717193MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Foxd3重組蛋白
  • 貨號：
    CSB-EP717193MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Foxd3重組蛋白
  • 貨號：
    CSB-BP717193MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Foxd3重組蛋白
  • 貨號：
    CSB-MP717193MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Foxd3; Hfh2Forkhead box protein D3; HNF3/FH transcription factor genesis; Hepatocyte nuclear factor 3 forkhead homolog 2; HFH-2
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    full length protein
  • 表達區域：
    1-465
  • 氨基酸序列
    MTLSGSGSAS DMSGQTVLTA EDVDIDVVGE GDDGLEEKDS DAGCDSPAGP PDLRLDEADE GPPVSAHHGQ SQPQALALPT EATGPGNDTG APEADGCKGG EDAVTGGGGP GAGSGATGGL TPNKPKNSLV KPPYSYIALI TMAILQSPQK KLTLSGICEF ISNRFPYYRE KFPAWQNSIR HNLSLNDCFV KIPREPGNPG KGNYWTLDPQ SEDMFDNGSF LRRRKRFKRH QQEHLREQTA LMMQSFGAYS LAAAAGAGPY GLHPAAAAGA YSHPAAAAAA AAAAALQYPY ALPPVAPVLP PAVPLLPSGE LGRKAAAFGS QLGPSLQLQL NTLGAAAAAA GTAGAAGTTS LIKSEPSARP SFSIENIIGA GSAAPGGSAG GGGSGGGAGG GGGSGGGGGA QSFLRPPGTV QSAALMATHQ PLSLSRTTAT IAPILSVPLS GQFLQPAASA AAAAAAAVQA KWPAQ
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. Promotes development of neural crest cells from neural tube progenitors. Restricts neural progenitor cells to the neural crest lineage while suppressing interneuron differentiation. Required for maintenance of pluripotent cells in the pre-implantation and peri-implantation stages of embryogenesis.
  • 基因功能參考文獻：
    1. FOXD3-AS1 serves as a sponge or as a competing endogenous noncoding RNA for miR-150, restricting its capability to promote cell growth and thereby exaggerating hyperoxia-induced lung epithelial cell death PMID: 28655711
    2. suggest that CHD7, Oct3/4, Sox2, and Nanog directly induce FoxD3 expression when stimulated by BMP2/Wnt3a signaling, that FoxD3 promotes Sox10 expression, and that histone H3K4 methylation play important roles in this process of neural crest-derived stem cell formation PMID: 27579714
    3. this study shows that Foxd3 suppresses the production of IL-10+ Breg cells by directly binding the IL-10 promoter PMID: 27995618
    4. FOXD3 modulates the developmental potential of pluripotent cells as they differentiate PMID: 26748757
    5. analysis of a cycle of activation and deactivation of Foxd3 required for exit from naive pluripotency and subsequent primordial germ cell specification PMID: 26748758
    6. Foxd3 poises enhancers in pluripotent stem cells by recruiting multiple epigenetic enzymes that together simultaneously initiate and repress enhancer activity. PMID: 26748757
    7. Foxd3 suppresses NFAT-mediated differentiation to maintain self-renewal of embryonic stem cells PMID: 25378483
    8. In a xenograft tumor model, FOXD3 overexpression inhibits tumor growth and angiogenesis. PMID: 26341266
    9. Data indicate that homeobox b5 (Hoxb5) regulated the neural crest (NC)development by directly inducing Forkhead box D3 gene (Foxd3). PMID: 25220476
    10. Foxd3 induced mutant ESCs precociously express genes required for mesoderm induction, but they are likely unable to differentiate into skeletal muscle. PMID: 24270162
    11. Foxd3 deficiency completely abolishes the sphere-forming potential of skin embryonic stem cells. PMID: 23316968
    12. Foxd3 is part of a dynamically expressed gene network that is necessary and sufficient to regulate fate decisions in premigratory neural crest cells. PMID: 23615280
    13. Methylation profile analyses identified the promoter of FOXD3 as the only genomic region with increased methylation in mice and humans during progression of Helicobacter pylori-associated gastric tumors. PMID: 23058321
    14. The findings highlighted the crucial roles played by Foxd3 during enteric nervous system development including progenitor proliferation, neural patterning, and glial differentiation. PMID: 22266424
    15. Foxd3 is upstream of several pathways critical for beta-cell mass expansion in vivo. PMID: 21952247
    16. Foxd3 and Pax3 act together to affect survival and maintenance of cardiac NC progenitors, and loss of these progenitors catastrophically affects key aspects of later cardiovascular development. PMID: 21254333
    17. show that Foxd3 mediates a fate restriction choice for multipotent neural crest (NC) progenitors with loss of Foxd3 biasing NC toward a mesenchymal fate PMID: 21228004
    18. In ESCs, binding of Foxd3 suppresses intergenic transcription of the enhancer and surrounding sequences. PMID: 20621055
    19. Trophoblast progenitors in Foxd3-/- embryos do not self-renew and are not multipotent, but instead give rise to an excess of trophoblast giant cells. PMID: 16039639
    20. Foxd3 transcriptional repressor plays role in all aspects of neural crest maintenance along the anterior-posterior axis, and establish an unprecedented molecular link between multiple divergent progenitor lineages of the mammalian embryo. PMID: 18367558
    21. A model for the role of Foxd3 in repressing differentiation, promoting self-renewal, and maintaining survival of mouse embryonic stem cells, is presented. PMID: 18653770

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus.
  • 組織特異性：
    Expressed in premigratory and migrating neural crest cells in the early embryo and in motorneuron and interneuron progenitors in the developing spinal cord.
  • 數據庫鏈接：


主站蜘蛛池模板： 狠狠色噜噜狠狠狠888米奇视频 | 天堂а√中文在线| 免费午夜男女高清视频 | 用舌头去添高潮无码视频| 精品少妇人妻av一区二区| 18禁无码永久免费无限制网站| 特黄做受又大又粗又长大片| 久精品视频在线观看免费| 亚洲人成色77777| 国产精品久久久久久无码| 久久五月丁香激情综合| 亚洲一区二区三区高清在线看| 国产日韩一区二区三区在线观看| 国产大片黄在线观看| 亚洲熟妇无码一区二区三区导航| 又黄又爽又高潮免费毛片| 欧美xxxxx在线观看| 精品av综合导航| 少女韩国电视剧在线观看完整 | 欧美大片18禁aaa免费视频| 亚洲精品中文字幕久久久久下载| 国内精品久久久久影院亚瑟| 亚州av综合色区无码一区| 少妇内射兰兰久久| 久久俺也去丁香综合色| 国内自拍五区| 三上悠亚ssⅰn939无码播放 | 久青草影院在线观看国产| 日本高清不卡aⅴ免费网站 | 狠狠色色综合站| av永久天堂一区二区三区| 亚洲日韩国产二区无码| 婷婷久久久亚洲欧洲日产国码av| 国产av巨作丝袜秘书| 日韩乱码人妻无码超清蜜桃| 与子敌伦刺激对白播放的优点| 欧美亚洲人成网站在线观看| 麻花传媒mv国产免费观看视频| 爆乳女仆高潮在线观看| 久久久精品区二区三区免费| 无码专区手机在线播放|