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  4. Recombinant Mouse F-actin-capping protein subunit alpha-3 (Capza3)

Recombinant Mouse F-actin-capping protein subunit alpha-3 (Capza3)

  • 中文名稱：
    Recombinant Mouse F-actin-capping protein subunit alpha-3(Capza3)
  • 貨號：
    CSB-YP004513MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    Recombinant Mouse F-actin-capping protein subunit alpha-3(Capza3)
  • 貨號：
    CSB-EP004513MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    Recombinant Mouse F-actin-capping protein subunit alpha-3(Capza3)
  • 貨號：
    CSB-EP004513MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    Recombinant Mouse F-actin-capping protein subunit alpha-3(Capza3)
  • 貨號：
    CSB-BP004513MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    Recombinant Mouse F-actin-capping protein subunit alpha-3(Capza3)
  • 貨號：
    CSB-MP004513MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
  • Uniprot No.：
  • 別名：
    Capza3; Cappa3; Gsg3F-actin-capping protein subunit alpha-3; CapZ alpha-3; Germ cell-specific protein 3
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full length protein
  • 表達區域：
    1-299
  • 氨基酸序列
    MSLSVLSRKE KEKVIHRLLV QAPPGEFVNA FDDLCLLIRD EKLMHHQGEC AGHQHCQKYC VPLCIDGNPV LLSHHNVMGD FRFFDYQSKL SFRFDLLQNQ LRDIQSHGII RNETEYLRSV VMCALKLYVN DHYPNGNCNV LRKTVKSKEF LIACIEDHSY DNGECWNGLW KSKWIFQVNP FLTQVTGRIF VQAHFFRCVN LHIEVSKDLK ESLEVVNQAQ LALSFARLVE EQENKFQAAV IEELQELSNE ALRKILRRDL PVTRTLIDWQ RILSDLNLVM YPKLGYVIYS RSVLCNWII
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. May play a role in the morphogenesis of spermatid.
  • 基因功能參考文獻：
    1. to understand actin-mediated change in protein localization during acrosome reaction, distribution of CAPZA3 was analyzed; like IZUMO1, CAPZA3 shows dynamic pattern of localization; movements follow different temporal pattern than changes seen with IZUMO1 PMID: 20458735
    2. CPalpha3 might play an important role in sperm morphogenesis and/or sperm function PMID: 18645673
    3. These observations strongly suggest the missense mutation in Capza3 is responsible for the mutant phenotype of repro32/repro32 sperm and regulation of F-actin dynamics PMID: 19341723
  • 蛋白家族：
    F-actin-capping protein alpha subunit family
  • 組織特異性：
    Exclusively expressed in the testis.
  • 數據庫鏈接：


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