在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c)

Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c)

  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-YP702804MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-EP702804MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-EP702804MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-MP702804MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Fam20c
  • Uniprot No.：
  • 別名：
    Fam20c; Dmp4; Kiaa4081Extracellular serine/threonine protein kinase FAM20C; EC 2.7.11.1; Dentin matrix protein 4; DMP-4; Golgi-enriched fraction casein kinase; GEF-CK
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    27-579
  • 氨基酸序列
    VDLL PKLDRRATRS SGEPGCSCAQ PAAEAAGPGW AQARSRPGES AGGDAGWPNK HTLRILQDFS SDPASNLTSH SLEKLPSAAE PVDHAPRGQE PRSPPPRDPA HRPLLRDPGP RPRVPPPGPS GDGSLLAKLF EHPLYQGAVP PLTEDDVLFN VNSDIRFNPK AAENPDWPHE GAEGAEFLPT GEAAVNLYPN WLKFHIGINR YELYSRHNPA IDALLRDLGS QKITSVAMKS GGTQLKLIMT FQNYGQALFK PMKQTREQET PPDFFYFSDY ERHNAEIAAF HLDRILDFRR VPPVAGRMIN MTKEIRDVTR DKKLWRTFFV SPANNICFYG ECSYYCSTEH ALCGRPDQIE GSLAAFLPDL SLAKRKTWRN PWRRSYHKRK KAEWEVDPDY CEEVKQTPPY DSGHRILDIM DMTVFDFLMG NMDRHHYETF EKFGNETFII HLDNGRGFGK YSHDELSILA PLHQCCRIRR STYLRLQLLA KEEHKLSLLM AESLQHDKVA PVLYQLHLEA LDRRLRIVLQ AVRDCVEKDG LSSVVEDDLA TEHRASTER
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth. Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome. Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity. Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1. In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion.
  • 基因功能參考文獻：
    1. that Fam20c indeed regulates cell behaviors and cell signaling pathway in a cell-autonomous manner PMID: 29337188
    2. family with sequence similarity member 20C is the primary, but not the only, kinase for the SIBLINGs PMID: 26324849
    3. Fam20A potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro. PMID: 25789606
    4. Loss of Fam20C function leads to periodontal disease in mice PMID: 25479552
    5. Successful generation of Fam20C-GFP transgenic mice will provide a unique model for studying Fam20C gene expression and the biological function of this gene during odontogenesis and osteogenesis PMID: 25537657
    6. we have successfully generated the immortalized mouse floxed Fam20c dental papilla mesenchymal and osteoblast cell lines. PMID: 25833681
    7. These results indicated that the downregulation of Dmp1 may not directly associate with, or significantly contribute to the bone and dentin defects in the Fam20C-cKO mice. PMID: 24874551
    8. that FAM20C is not a constituent of the enamel extracellular matrix and functions intracellularly within ameloblasts. PMID: 23703840
    9. FAM20C is a molecule essential to amelogenesis, its inactivation in the dental epithelium does not significantly affect dentinogenesis. PMID: 24026952
    10. FAM20C is essential to the differentiation and mineralization of dental tissues through the regulation of molecules critical to the differentiation of tooth-formative cells. PMID: 22936805
    11. Our findings indicate that FAM20C is essential to the differentiation of osteoblasts/osteocytes and is involved in the regulation of phosphate homeostasis via the mediation of FGF23 PMID: 22615579
    12. Fam20c null mice develop hypophosphatemic rickets and defective enamel and dentin PMID: 22732358
    13. temporospatial expression profile of FAM20C PMID: 20644212
    14. This study defines the causative role of FAM20C in this lethal osteosclerotic disorder and its crucial role in normal bone development. PMID: 17924334

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Golgi apparatus.
  • 蛋白家族：
    FAM20 family
  • 組織特異性：
    Highly expressed in the tooth. No expression in the dental pulp. At the secretory stage of amelogenesis, it is detected in the matrix of the enamel, in the ameloblasts, and within the cells adjoining the stratum intermedium (a tissue layer analogous to th
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 99偷拍视频精品一区二区 | 精品av一区二区久久久| 黑人与人妻无码中字视频| 真实国产乱子伦对白在线播放| 国产亚洲精品a在线观看下载| 成av人片一区二区三区久久| 国产天美传媒性色av| 国模无码视频一区| 国产精品无码av天天爽| 亚洲mv国产mv在线mv综合试看| 欧美午夜片欧美片在线观看| 欧洲专线一区二区三区| 爱情岛论坛网亚洲品质| 亚洲人成中文字幕在线观看| 我和亲妺妺乱的性视频| 无码少妇一区二区三区芒果| 四虎国产精品一区二区| 天堂久久天堂av色综合| 无遮18禁在线永久免费观看挡| 无码一区二区三区视频| 大地资源网中文第五页| 欧美午夜精品久久久久久浪潮| 亚洲中文字幕无码久久2020| 伊人成伊人成综合网222| 麻花豆传媒剧国产免费mv观看| 天堂а√8在线最新版在线| 欧美熟妇另类久久久久久不卡| 欧美猛少妇色xxxxx猛叫| 亚洲熟妇av乱码在线观看| 最近免费中文字幕大全免费版视频| 99热国产这里只有精品9| 精品国产av一区二区果冻传媒| 国产成人精品手机在线观看| 亚洲人成色777777老人头| 久久不见久久见中文字幕免费| 国模小婕私拍鲜嫩玉门| 国产sm鞭打折磨调教视频| 欲女熟妇国产一区二区| 国产又色又爽又刺激在线播放| 狠狠色综合7777久夜色撩人ⅰ| 久久久中文字幕日本无吗|