在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c)

Recombinant Mouse Extracellular serine/threonine protein kinase FAM20C (Fam20c)

  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-YP702804MO
  • 規(guī)格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-EP702804MO
  • 規(guī)格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-EP702804MO-B
  • 規(guī)格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Fam20c重組蛋白
  • 貨號：
    CSB-MP702804MO
  • 規(guī)格：
  • 來源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Fam20c
  • Uniprot No.：
  • 別名：
    Fam20c; Dmp4; Kiaa4081Extracellular serine/threonine protein kinase FAM20C; EC 2.7.11.1; Dentin matrix protein 4; DMP-4; Golgi-enriched fraction casein kinase; GEF-CK
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區(qū)域：
    27-579
  • 氨基酸序列
    VDLL PKLDRRATRS SGEPGCSCAQ PAAEAAGPGW AQARSRPGES AGGDAGWPNK HTLRILQDFS SDPASNLTSH SLEKLPSAAE PVDHAPRGQE PRSPPPRDPA HRPLLRDPGP RPRVPPPGPS GDGSLLAKLF EHPLYQGAVP PLTEDDVLFN VNSDIRFNPK AAENPDWPHE GAEGAEFLPT GEAAVNLYPN WLKFHIGINR YELYSRHNPA IDALLRDLGS QKITSVAMKS GGTQLKLIMT FQNYGQALFK PMKQTREQET PPDFFYFSDY ERHNAEIAAF HLDRILDFRR VPPVAGRMIN MTKEIRDVTR DKKLWRTFFV SPANNICFYG ECSYYCSTEH ALCGRPDQIE GSLAAFLPDL SLAKRKTWRN PWRRSYHKRK KAEWEVDPDY CEEVKQTPPY DSGHRILDIM DMTVFDFLMG NMDRHHYETF EKFGNETFII HLDNGRGFGK YSHDELSILA PLHQCCRIRR STYLRLQLLA KEEHKLSLLM AESLQHDKVA PVLYQLHLEA LDRRLRIVLQ AVRDCVEKDG LSSVVEDDLA TEHRASTER
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評價

靶點詳情

  • 功能：
    Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth. Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome. Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity. Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1. In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion.
  • 基因功能參考文獻：
    1. that Fam20c indeed regulates cell behaviors and cell signaling pathway in a cell-autonomous manner PMID: 29337188
    2. family with sequence similarity member 20C is the primary, but not the only, kinase for the SIBLINGs PMID: 26324849
    3. Fam20A potentiates Fam20C kinase activity and promotes the phosphorylation of enamel matrix proteins in vitro. PMID: 25789606
    4. Loss of Fam20C function leads to periodontal disease in mice PMID: 25479552
    5. Successful generation of Fam20C-GFP transgenic mice will provide a unique model for studying Fam20C gene expression and the biological function of this gene during odontogenesis and osteogenesis PMID: 25537657
    6. we have successfully generated the immortalized mouse floxed Fam20c dental papilla mesenchymal and osteoblast cell lines. PMID: 25833681
    7. These results indicated that the downregulation of Dmp1 may not directly associate with, or significantly contribute to the bone and dentin defects in the Fam20C-cKO mice. PMID: 24874551
    8. that FAM20C is not a constituent of the enamel extracellular matrix and functions intracellularly within ameloblasts. PMID: 23703840
    9. FAM20C is a molecule essential to amelogenesis, its inactivation in the dental epithelium does not significantly affect dentinogenesis. PMID: 24026952
    10. FAM20C is essential to the differentiation and mineralization of dental tissues through the regulation of molecules critical to the differentiation of tooth-formative cells. PMID: 22936805
    11. Our findings indicate that FAM20C is essential to the differentiation of osteoblasts/osteocytes and is involved in the regulation of phosphate homeostasis via the mediation of FGF23 PMID: 22615579
    12. Fam20c null mice develop hypophosphatemic rickets and defective enamel and dentin PMID: 22732358
    13. temporospatial expression profile of FAM20C PMID: 20644212
    14. This study defines the causative role of FAM20C in this lethal osteosclerotic disorder and its crucial role in normal bone development. PMID: 17924334

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Golgi apparatus.
  • 蛋白家族：
    FAM20 family
  • 組織特異性：
    Highly expressed in the tooth. No expression in the dental pulp. At the secretory stage of amelogenesis, it is detected in the matrix of the enamel, in the ameloblasts, and within the cells adjoining the stratum intermedium (a tissue layer analogous to th
  • 數(shù)據(jù)庫鏈接：


主站蜘蛛池模板： 人妻丰满熟妇av无码片| 精品影片在线观看的网站| 久久亚洲精品中文字幕| 亚洲精品无码专区在线观看| 一区二区三区国产精华液| 中字幕视频在线永久在线观看免费 | 欧美性猛交xxxx乱大交极品| 国产亚洲福利在线视频| 野外性史欧美k8播放| 精品久久香蕉国产线看观看亚洲| 久久人人爽人人爽人人av东京热| 国产亚洲精品久久久久久国| 亚洲男人的天堂在线aⅴ视频| 无码人妻少妇伦在线电影| 男女啪啪做爰高潮无遮挡| 啪啪激情婷婷久久婷婷色五月| 亚洲人成人无码www影院| 内射无码专区久久亚洲| 在线观看一区二区三区国产免费 | 尤物国产在线精品福利三区| 日韩欧美精品有码在线| 青青草视频在线观看| 自慰小少妇毛又多又黑流白浆| 国产精品无码a∨果冻传媒| 国产精品人妻久久久久| 老熟女高潮一区二区三区| 久久综合精品无码av一区二区三区| 国产成人亚洲精品无码青青草原| 激情综合婷婷色五月蜜桃 | 国产乱人伦av麻豆网| 亚洲乱亚洲乱妇中文影视| 成人免费无码不卡毛片| 亚洲国产精品一区二区www| 影音先锋在线资源无码| 国产麻豆一精品av一免费软件| 亚洲欧洲精品成人久久曰影片| 国产精品久久久久久吹潮| 亚洲伊人成综合人影院青青青 | 成人网站免费观看入口| 久久亚洲日韩av一区二区三区| 国产精品va无码免费|