在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Recombinant Mouse Exportin-5 (Xpo5), partial

  • 中文名稱:
    小鼠Xpo5重組蛋白
  • 貨號:
    CSB-YP849753MO
  • 說明書:
  • 規格:
  • 來源:
    Yeast
  • 其他:
  • 中文名稱:
    小鼠Xpo5重組蛋白
  • 貨號:
    CSB-EP849753MO
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 其他:
  • 中文名稱:
    小鼠Xpo5重組蛋白
  • 貨號:
    CSB-EP849753MO-B
  • 說明書:
  • 規格:
  • 來源:
    E.coli
  • 共軛:
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他:
  • 中文名稱:
    小鼠Xpo5重組蛋白
  • 貨號:
    CSB-BP849753MO
  • 說明書:
  • 規格:
  • 來源:
    Baculovirus
  • 其他:
  • 中文名稱:
    小鼠Xpo5重組蛋白
  • 貨號:
    CSB-MP849753MO
  • 說明書:
  • 規格:
  • 來源:
    Mammalian cell
  • 其他:

產品詳情

  • 純度:
    >85% (SDS-PAGE)
  • 基因名:
    Xpo5
  • Uniprot No.:
  • 別名:
    Xpo5; Kiaa1291; Ranbp21; Exportin-5; Exp5; Ran-binding protein 21
  • 種屬:
    Mus musculus (Mouse)
  • 蛋白長度:
    Partial
  • 蛋白標簽:
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式:
    Lyophilized powder Warning: in_array() expects parameter 2 to be array, null given in /www/web/cusabio_cn/public_html/caches/caches_template/default/content/show_product_protein.php on line 662
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶:
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件:
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期:
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期:
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項:
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet :
    Please contact us to get it.

產品評價

靶點詳情

  • 功能:
    Mediates the nuclear export of proteins bearing a double-stranded RNA binding domain (dsRBD) and double-stranded RNAs (cargos). XPO5 in the nucleus binds cooperatively to the RNA and to the GTPase Ran in its active GTP-bound form. Proteins containing dsRBDs can associate with this trimeric complex through the RNA. Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins. Upon transit of a nuclear export complex into the cytoplasm, hydrolysis of Ran-GTP to Ran-GDP (induced by RANBP1 and RANGAP1, respectively) cause disassembly of the complex and release of the cargo from the export receptor. XPO5 then returns to the nuclear compartment by diffusion through the nuclear pore complex, to mediate another round of transport. The directionality of nuclear export is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. Overexpression may in some circumstances enhance RNA-mediated gene silencing (RNAi). Mediates nuclear export of ADAR/ADAR1 in a RanGTP-dependent manner.; Mediates the nuclear export of micro-RNA precursors, which form short hairpins. Also mediates the nuclear export of synthetic short hairpin RNAs used for RNA interference. In some circumstances can also mediate the nuclear export of deacylated and aminoacylated tRNAs. Specifically recognizes dsRNAs that lack a 5'-overhang in a sequence-independent manner, have only a short 3'-overhang, and that have a double-stranded length of at least 15 base-pairs. Binding is dependent on Ran-GTP.
  • 基因功能參考文獻:
    1. productive reoviral infection is strongly correlated with elevated importin-beta and exportin-5 levels which may serve as biomarkers of the disease in clinical specimens PMID: 29414394
    2. miRNA biogenesis components Drosha, Dgcr8, Exportin-5 and Dicer1 are expressed in the mouse uterus and that Exportin-5 and Dicer1 appear to be the major steroid regulated components in the miRNA biogenesis pathway PMID: 20852728
    3. Exp5 exports eEF1A via tRNA from nuclei and synergizes with other transport pathways to confine translation to the cytoplasm. PMID: 12426392
  • 亞細胞定位:
    Nucleus. Cytoplasm.
  • 蛋白家族:
    Exportin family
  • 數據庫鏈接:


主站蜘蛛池模板: 香蕉伊蕉伊中文视频在线| 真人二十三式性视频(动)| 亚洲乱亚洲乱少妇无码99p| 暖暖 免费 高清 日本 在线| 亚洲欧洲成人a∨在线观看| 午夜三级a三级三点在线观看 | 寂寞骚妇被后入式爆草抓爆| 亚洲精品国产自在现线看| 中国少妇xxxx做受| 男女做爰猛烈叫床视频免费| √最新版天堂资源在线| 无码三级国产三级在线电影| 日本乱码伦午夜福利在线 | 老司机在线精品视频网站| 欧美黑人激情性久久| 国产精品美女久久久| 揉捏奶头高潮呻吟视频| 欧美色偷偷亚洲天堂bt| 国产精品无码一区二区在线观一| 少妇av一区二区三区无码| 成人区人妻精品一区二区不卡视频 | 欧美黑人性暴力猛交喷水| 日本熟妇中文字幕三级| 人人澡超碰碰97碰碰碰| 亚洲色无码专区在线播放| 欧美老妇乱辈通奷| 影音先锋无码aⅴ男人资源站| 人与禽性视频77777| 野外被强j到高潮免费观看| 国产精品天干天干| 韩产日产国产欧产| 人妻综合专区第一页| 色优久久久久综合网鬼色| 久久精品无码中文字幕| 中文字幕av久久激情亚洲精品| 99久久久国产精品消防器材| 亚洲色大成网站www永久| 亚洲爆乳无码专区www| 夜晚成人18禁区导航网站| 国产精品久久久久久久久久久免费看 | 好男人社区影院www|