在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Eukaryotic translation initiation factor 3 subunit E (Eif3e)

Recombinant Mouse Eukaryotic translation initiation factor 3 subunit E (Eif3e)

  • 中文名稱：
    小鼠Eif3e重組蛋白
  • 貨號：
    CSB-YP007534MO
  • 規格：
  • 來源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Eif3e重組蛋白
  • 貨號：
    CSB-EP007534MO
  • 規格：
  • 來源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Eif3e重組蛋白
  • 貨號：
    CSB-EP007534MO-B
  • 規格：
  • 來源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Eif3e重組蛋白
  • 貨號：
    CSB-BP007534MO
  • 規格：
  • 來源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Eif3e重組蛋白
  • 貨號：
    CSB-MP007534MO
  • 規格：
  • 來源：
    Mammalian cell
  • 其他：

產品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Eif3e
  • Uniprot No.：
  • 別名：
    Eif3e; Eif3s6; Int6Eukaryotic translation initiation factor 3 subunit E; eIF3e; Eukaryotic translation initiation factor 3 subunit 6; MMTV integration site 6; Mammary tumor-associated protein INT-6; Viral integration site protein INT-6; eIF-3 p48
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長度：
    Full Length of Mature Protein
  • 表達區域：
    2-445
  • 氨基酸序列
    AEYDLTTRI AHFLDRHLVF PLLEFLSVKE IYNEKELLQG KLDLLSDTNM VDFAMDVYKN LYSDDIPHAL REKRTTVVAQ LKQLQAETEP IVKMFEDPET TRQMQSTRDG RMLFDYLADK HGFRQEYLDT LYRYAKFQYE CGNYSGAAEY LYFFRVLVPA TDRNALSSLW GKLASEILMQ NWDAAMEDLT RLKETIDNNS VSSPLQSLQQ RTWLIHWSLF VFFNHPKGRD NIIDLFLYQP QYLNAIQTMC PHILRYLTTA VITNKDVRKR RQVLKDLVKV IQQESYTYKD PITEFVECLY VNFDFDGAQK KLRECESVLV NDFFLVACLE DFIENARLFI FETFCRIHQC ISINMLADKL NMTPEEAERW IVNLIRNARL DAKIDSKLGH VVMGNNAVSP YQQVIEKTKS LSFRSQMLAM NIEKKLNQNS RSEAPNWATQ DSGFY
  • 蛋白標簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產品評價

靶點詳情

  • 功能：
    Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression. Required for nonsense-mediated mRNA decay (NMD); may act in conjunction with UPF2 to divert mRNAs from translation to the NMD pathway. May interact with MCM7 and EPAS1 and regulate the proteasome-mediated degradation of these proteins.
  • 基因功能參考文獻：
    1. eIF3e is an angiogenesis suppressor. Silencing of eIF3e promotes blood perfusion recovery after limb ischemia through stabilization of hypoxia-inducible factor 2alpha activity. PMID: 25758454
    2. expression of 3e5 diminishes eIF4G interaction with eIF3 and causes abnormal gene expression at the translational level. PMID: 21737453
    3. the pathway involving INT6/HIF2alpha acts as a hypoxia-independent master switch of functional angiogenesis PMID: 20713899
    4. Truncated Int6/eIF3e expression in mammary alveolar epithelium is associated with hyperplasia and tumorigenesis PMID: 17626637
  • 相關疾?。?/div>
    EIF3E serves as a site for viral integration of mouse mammary tumor virus (MMTV) in mammary tumors. MMTV integration into EIF3E can result in EIF3E truncation and expression of chimeric RNA species which terminate at a cryptic transcription stop signal in the reverse U3 portion of the MMTV long terminal repeat. This causes deregulation of the normal control of mammary epithelial cell growth.
  • 亞細胞定位：
    Cytoplasm. Nucleus, PML body.
  • 蛋白家族：
    EIF-3 subunit E family
  • 組織特異性：
    Ubiquitously expressed.
  • 數據庫鏈接：


主站蜘蛛池模板： 国产精品久久久久不卡绿巨人| 顶级少妇做爰视频在线观看 | 国产精品久久久久av| 麻豆丰满少妇chinese| 在线播放亚洲人成电影| 中文字幕乱偷无码av先锋| 国产免费毛卡片| 日本狂喷奶水在线播放212| 亚洲麻豆av成本人无码网站| 久久国产精品无码网站| 99re热这里只有精品视频| 国产高潮流白浆免费观看| 韩国三级l中文字幕无码| 亚洲 a v无 码免 费 成 人 a v | 亚洲制服有码在线丝袜| 亚洲一卡2卡3卡4卡5卡乱码观看| 国产精品h片在线播放| 曰韩少妇内射免费播放| 中文字幕奈奈美被公侵犯| 天天爽夜夜爽人人爽免费| 中文在线8资源库| 中文天堂在线www最新版官网| 人人爽久久久噜噜噜婷婷| 国产精品喷浆| 国语对白做受xxxxx在线中国| 又黄又硬又湿又刺激视频免费 | 在线中文字幕亚洲日韩2020| 99久久国产热无码精品免费| av无码中文一区二区三区四区 | 蜜臀久久99精品久久久久久| 亚洲欧美日韩综合在线一| 2021久久超碰国产精品最新| 亚洲熟妇无码另类久久久| 爱性久久久久久久久| 国产做a爱免费视频在线观看 | 精品国产黑色丝袜高跟鞋| 色妺妺免费影院| 伊人久久大香线蕉综合中文字幕| 夜夜爽妓女8888视频免费观看 | 国产鲁鲁视频在线观看| 免费无码va一区二区三区|