在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. 首頁(yè)
  2. 蛋白
  3. 重組蛋白
  4. Recombinant Mouse Epithelial splicing regulatory protein 1 (Esrp1)

Recombinant Mouse Epithelial splicing regulatory protein 1 (Esrp1)

  • 中文名稱：
    小鼠Esrp1重組蛋白
  • 貨號(hào)：
    CSB-YP007832MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Yeast
  • 其他：
  • 中文名稱：
    小鼠Esrp1重組蛋白
  • 貨號(hào)：
    CSB-EP007832MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 其他：
  • 中文名稱：
    小鼠Esrp1重組蛋白
  • 貨號(hào)：
    CSB-EP007832MO-B
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    E.coli
  • 共軛：
    Avi-tag Biotinylated

    E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.

  • 其他：
  • 中文名稱：
    小鼠Esrp1重組蛋白
  • 貨號(hào)：
    CSB-BP007832MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Baculovirus
  • 其他：
  • 中文名稱：
    小鼠Esrp1重組蛋白
  • 貨號(hào)：
    CSB-MP007832MO
  • 說(shuō)明書(shū)：
  • 規(guī)格：
  • 來(lái)源：
    Mammalian cell
  • 其他：

產(chǎn)品詳情

  • 純度：
    >85% (SDS-PAGE)
  • 基因名：
    Esrp1
  • Uniprot No.：
  • 別名：
    Epithelial splicing regulatory protein 1; Epithelial splicing regulatory protein 2; Esrp1; ESRP1_MOUSE; ESRP2; PP7059; RNA binding motif protein 35B; RNA-binding motif protein 35A; RNA-binding motif protein 35B; RNA-binding protein 35A; RNA-binding protein 35B
  • 種屬：
    Mus musculus (Mouse)
  • 蛋白長(zhǎng)度：
    full length protein
  • 表達(dá)區(qū)域：
    1-680
  • 氨基酸序列
    MTASPDYLVV LFGITAGATG AKLGSDEKEL ILLLWKVVDL ANKKVGQLHE VLVRPDQLEL TEDCKEETKI DAENLSSAPQ LDQALRQFNQ SVSNELNIGV GTSFCLCTDG QLHIRQILHP EASKKNVLLP ECFYSFFDLR KEFKKCCPGS PDIDKLDVAA MTESLNFEKS DSVSRYGASQ VEDMGNIILA MISEPYNHRF SDPERVNYKF ESGTCKMELI DDSTVVRARG LPWQSSDQDI ARFFKGLNIA KGGAALCLNA QGRRNGEALV RFVSEEHRDL ALQRHKHHMG TRYIEVYKAT GEDFLKIAGG TSNEVAQFLS KENQVIVRMR GLPFTATAEE VVAFFGQHCP ITGGKEGILF VTYPDGRPTG DAFVLFACEE YAQNALRKHK ELLGKRYIEL FRSTAAEVQQ VLNRFSSAPL IPLPTPPIIP VLPQQFVPPT NVRDCIRLRG LPYAATIEDI LDFLGEFSTD IRTHGVHMVL NHQGRPSGDA FIQMKSTDRA FMAAQKYHKK TMKDRYVEVF QCSAEEMNFV LMGGTLNRNG LSPPPCKLPC LSPPSYTFPA PTAVIPTEAA IYQPSLLLNP RALQPSTAYY PAGTQLFMNY TAYYPSPPGS PNSLGYFPTA ANLSSVPPQP GTVVRMQGLA YNTGVKEILN FFQGYQYATE DGLVHTNDQA RTLPKEWVCI
  • 蛋白標(biāo)簽：
    Tag?type?will?be?determined?during?the?manufacturing?process.
    The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
  • 產(chǎn)品提供形式：
    Lyophilized powder
    Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
  • 復(fù)溶：
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
  • 儲(chǔ)存條件：
    Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
  • 保質(zhì)期：
    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
    Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
  • 貨期：
    Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
    Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
  • 注意事項(xiàng)：
    Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Datasheet ：
    Please contact us to get it.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    mRNA splicing factor that regulates the formation of epithelial cell-specific isoforms. Specifically regulates the expression of FGFR2-IIIb, an epithelial cell-specific isoform of FGFR2. Also regulates the splicing of CD44, CTNND1, ENAH, 3 transcripts that undergo changes in splicing during the epithelial-to-mesenchymal transition (EMT). Acts by directly binding specific sequences in mRNAs. Binds the GU-rich sequence motifs in the ISE/ISS-3, a cis-element regulatory region present in the mRNA of FGFR2. Regulates splicing and expression of genes involved in inner ear development, auditory hair cell differentiation, and cell fate specification in the cochlear epithelium.
  • 基因功能參考文獻(xiàn)：
    1. Study documented the expression of Esrp1 during gonadal development and in differentiating cells of the adult gonads: in mouse fetal gonads, Esrp1 mRNA was specifically detected in germ cells of either sex and absent from somatic gonadal cells. Esrp1 mRNA was present in a gonocyte-enriched cell fraction and in all germ cells examined in postnatal testis. PMID: 29324788
    2. Findings reveal that Esrp1-regulated splicing in ureteric epithelial cells plays an important role in renal development. Defects in Esrp1 KO kidneys likely reflect reduced and/or absent ureteric branching, leading to decreased nephron induction secondary to incorrect Fgfr2 splicing and other splicing alterations PMID: 27404344
    3. implicate mutations in Epithelial Splicing-Regulatory Protein 1 as a cause of SNHL and demonstrate the complex interplay between alternative splicing PMID: 29107558
    4. ESRP1 thus acts as a physiological regulator of the finely-tuned balance between self-renewal and commitment to a restricted developmental fate. PMID: 24015231
    5. Esrp1 could play an important role in the morphological changes underlying embryogenesis of the placenta and embryo. PMID: 23233200
    6. Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell. PMID: 22673910

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    ESRP family
  • 組織特異性：
    Epithelial cell-specific. Epithelial-specific expression in diverse tissues and organs with particularly notable levels of expression in skin and gastrointestinal epithelia.
  • 數(shù)據(jù)庫(kù)鏈接：


主站蜘蛛池模板： 无码免费毛片手机在线无卡顿| 国产乱辈通伦影片在线播放亚洲| 国产露脸150部国语对白| 女人爽到高潮免费视频大全| 亚洲欧美日本久久综合网站| 国产又粗又黄又爽的大片| 亚洲午夜福利在线视频| 午夜精品一区二区三区的区别| 人妻少妇久久中文字幕456| 做性久久久久久| 好爽又高潮了毛片免费下载| 亚洲精品乱码久久久久久日本| 97se亚洲国产综合自在线尤物| 精品性影院一区二区三区内射 | 亚洲欧美人成网站在线观看看| 超清中文乱码一区| 一本精品中文字幕在线| 亚洲高清国产拍精品网络战| 国产一区丝袜高跟鞋| 久久精品国产精品国产精品污 | 人妻熟女一区二区aⅴ千叶宁真 | 欧美精品v欧洲精品| 午夜精品一区二区三区在线观看| 色狠狠色噜噜av天堂一区| 亚洲欧美综合精品成人网| 狠狠做五月深爱婷婷| 性高湖久久久久久久久aaaaa| 日产幕无线码三区在线| 亚洲国产精品无码av| 无套中出丰满人妻无码| 狠狠色丁香久久婷婷综合图片| 精品日本免费一区二区三区| 国产公开免费人成视频| 狠狠热精品免费视频| 中文字幕乱码一区二区三区免费| 护士奶头又大又软又好摸| 人妻熟女一区| 永久免费的av片在线电影网| 亚洲国产成人精品激情姿源| 欧美黑人又粗又大又爽免费| 99久无码中文字幕一本久道|